A Metal-Free DNA Nuclease Based on a Cyclic Peptide Scaffold

2010 ◽  
Vol 21 (8) ◽  
pp. 1425-1431 ◽  
Author(s):  
Shadad Alkhader ◽  
Aviva Ezra ◽  
Jana Kasparkova ◽  
Viktor Brabec ◽  
Eylon Yavin
Keyword(s):  
Cyclic Peptide ◽  
Metal Free ◽  
Free Dna

Metal-Free DNA Linearized Nuclease Based on PASP–Polyamine Conjugates

2012 ◽  
Vol 23 (9) ◽  
pp. 1832-1837 ◽  
Author(s):  
Chao Li ◽  
Fangfang Zhao ◽  
Yunan Huang ◽  
Xueyuan Liu ◽  
Yan Liu ◽  
...  
Keyword(s):  
Metal Free ◽  
Free Dna ◽  
Polyamine Conjugates

New Method for the Synthesis of a Mononucleating Cyclic Peptide Ligand, Crystal Structures of its Ni, Zn, Cu, and Co Complexes, and Their Inhibitory Bioactivity Against Urease

2007 ◽  
Vol 60 (5) ◽  
pp. 375 ◽  
Author(s):  
Kui Cheng ◽  
Zhong-Lu You ◽  
Hai-Liang Zhu
Keyword(s):  
Cyclic Peptide ◽  
Peptide Ligand ◽  
Jack Bean Urease ◽  
One Pot ◽  
Nickel Ion ◽  
Jack Bean ◽  
Metal Free ◽  
Synthetic Procedure ◽  
First Time ◽  
Solvothermal Conditions

A novel cyclic peptide complex, NiL 1 (H2L = 12,24-dihydroxy-1,6-dioxo-2,5,14,17-tetraaza[6*6]metacyclophane-13,17-diene has been synthesized for the first time under solvothermal conditions through a one-pot synthetic procedure using nickel ion as the template reagent. It was found that other metal ions were not suitable for the direct template reagent in this reaction. The nickel ion was eliminated from the complex and the metal-free cyclic peptide ligand H2L was obtained through a series of reactions. Then, ZnII, CuII, and CoII were coordinated with H2L under the same solvothermal conditions to produce three isomorphous complexes ZnL 2, CuL 3, and CoL 4. Their inhibitory bioactivities against urease were then studied. The copper(ii) complex 3 was the strongest inhibitor against jack bean urease, while H2L, 2, and 4 showed weak or no inhibitory activity against this enzyme.

Synthesis of [12]aneN3–dipeptide conjugates as metal-free DNA nucleases

2012 ◽  
Vol 22 (6) ◽  
pp. 2303-2307 ◽  
Author(s):  
Zhi-Fen Li ◽  
Hua-Long Chen ◽  
Li-Jun Zhang ◽  
Zhong-Lin Lu
Keyword(s):  
Metal Free ◽  
Free Dna

The Shadow Widths of Very Small Particles are Formed Independently of the Metal Cap Build Up on the Particle

1981 ◽  
Vol 39 ◽  
pp. 568-569
Author(s):  
George C. Ruben
Keyword(s):  
Gold Particle ◽  
Film Surface ◽  
Small Particles ◽  
Geometric Process ◽  
Metal Free ◽  
Shadow Area

The formation of shadows behind small particles has been thought to be a geometric process (GP) where the metal cap build up on the particle creates a shadow width the same size as or larger than the particle. This GP cannot explain why gold particle shadow widths are generally larger than the gold particle and may have no appreciable metal cap build up (fig. 1). Ruben and Telford have suggested that particle shadow widths are formed by the width dependent deflection of shadow metal (SM) lateral to and infront of the particle. The trajectory of the deflected SM is determined by the incoming shadow angle (45°). Since there can be up to 1.4 times (at 45°) more SM directly striking the particle than the film surface, a ridge of metal nuclei lateral to and infront of the particle can be formed. This ridge in turn can prevent some SM from directly landing in the metal free shadow area. However, the SM that does land in the shadow area (not blocked by the particle or its ridge) does not stick and apparently surface migrates into the SM film behind the particle.

Recent advancement in the electrocatalytic synthesis of ammonia

Nanoscale ◽  
2020 ◽  
Vol 12 (15) ◽  
pp. 8065-8094 ◽  
Author(s):  
Xudong Wen ◽  
Jingqi Guan
Keyword(s):  
Metal Oxide ◽  
Oxide Catalysts ◽  
Single Atom ◽  
Metal Oxide Catalysts ◽  
Metal Free ◽  
Recent Advancement ◽  
Nanocomposite Catalysts

Different kinds of electrocatalysts used in NRR electrocatalysis (including single atom catalysts, metal oxide catalysts, nanocomposite catalysts, and metal free catalysts) are introduced.

Transition-metal-free catalytic hydroboration reduction of amides to amines

2020 ◽  
Vol 7 (21) ◽  
pp. 3515-3520
Author(s):  
Wubing Yao ◽  
Jiali Wang ◽  
Aiguo Zhong ◽  
Shiliang Wang ◽  
Yinlin Shao
Keyword(s):  
Transition Metal ◽  
Selective Catalytic Reduction ◽  
Catalytic Reduction ◽  
Value Added ◽  
Metal Free

The selective catalytic reduction of amides to value-added amine products is a desirable but challenging transformation.

Deaminative carbonylative thioesterification of activated alkylamines with thiophenols under transition-metal-free conditions

2021 ◽  
Author(s):  
Fengqian Zhao ◽  
Xiao-Feng Wu
Keyword(s):  
Free Radical ◽  
Transition Metal ◽  
Metal Free

A transition-metal-free radical carbonylation of activated alkylamines with thiophenols has been successfully developed. Various thioesters were selectively produced with moderate to good yields.

Sign in / Sign up

Export Citation Format

Share Document