scholarly journals In Vivo Evaluation of64Cu-Labeled Magnetic Nanoparticles as a Dual-Modality PET/MR Imaging Agent

2010 ◽  
Vol 21 (4) ◽  
pp. 715-722 ◽  
Author(s):  
Charles Glaus ◽  
Raffaella Rossin ◽  
Michael J. Welch ◽  
Gang Bao
Keyword(s):  
Magnetic Nanoparticles ◽  
Mr Imaging ◽  
Imaging Agent ◽  
In Vivo Evaluation ◽  
Dual Modality

Synthesis and in vivo evaluation of [18F]N-(2-benzofuranylmethyl)-N′-[4-(2-fluoroethoxy)benzyl]piperazine, a novel σ1 receptor PET imaging agent

2011 ◽  
Vol 21 (22) ◽  
pp. 6820-6823 ◽  
Author(s):  
Iman A. Moussa ◽  
Samuel D. Banister ◽  
Nicolas Giboureau ◽  
Steven R. Meikle ◽  
Michael Kassiou
Keyword(s):  
Pet Imaging ◽  
Imaging Agent ◽  
In Vivo Evaluation ◽  
Σ1 Receptor

scholarly journals Intrinsically Germanium-69-Labeled Iron Oxide Nanoparticles: Synthesis and In-Vivo Dual-Modality PET/MR Imaging

2014 ◽  
Vol 26 (30) ◽  
pp. 5119-5123 ◽  
Author(s):  
Rubel Chakravarty ◽  
Hector F. Valdovinos ◽  
Feng Chen ◽  
Christina M. Lewis ◽  
Paul A. Ellison ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Mr Imaging ◽  
Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Dual Modality ◽  
Nanoparticles Synthesis

Radiosynthesis and in vivo evaluation of [ 11 C]MOV as a PET imaging agent for COX-2

2018 ◽  
Vol 28 (14) ◽  
pp. 2432-2435 ◽  
Author(s):  
Jaya Prabhakaran ◽  
Mark Underwood ◽  
Francesca Zanderigo ◽  
Norman R. Simpson ◽  
Anna R. Cooper ◽  
...  
Keyword(s):  
Pet Imaging ◽  
Imaging Agent ◽  
In Vivo Evaluation ◽  
Cox 2

Coordination polymer hybridized Au nanocages: a nanoplatform for dual-modality imaging guided near-infrared driven photothermal therapy in vivo

2017 ◽  
Vol 5 (44) ◽  
pp. 8761-8769 ◽  
Author(s):  
Congyang Yan ◽  
Lili Cui ◽  
Qi Yang ◽  
Xiaobao Zhou ◽  
Lixing Pan ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Coordination Polymer ◽  
Mr Imaging ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Dual Modality ◽  
Dual Modality Imaging

Coordination polymer hybridized Au nanocages (AuNC@CPs) were prepared, which were used for near-infrared (NIR)-driven photothermal therapy (PTT) guided by photoacoustic (PA) and magnetic resonance (MR) imaging in vivo.

scholarly journals Organic nanoparticle-doped microdroplets as dual-modality contrast agents for ultrasound microvascular flow and photoacoustic imaging

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Yu Xu ◽  
Guoyun Sun ◽  
Eshu Middha ◽  
Yu-Hang Liu ◽  
Kim Chuan Chan ◽  
...  
Keyword(s):  
Blood Flow ◽  
Nude Mice ◽  
Photoacoustic Imaging ◽  
Imaging Techniques ◽  
Contrast Effects ◽  
In Vivo Evaluation ◽  
Dual Modality ◽  
In Vivo Experiments

Abstract Tumor blood vessels are chaotic and abundantly distributed, owing to their heterogeneity. Therefore, imaging techniques which reveal abnormalities of tumor vasculature play significant roles in both mechanistic and clinical diagnostic tumor studies. Photoacoustic (PA) imaging uses the intrinsic characteristics of hemoglobin, to acquire tumor hemodynamic information, while ultrasound (US) imaging provides information about tumoral vessel structures and blood flow. To improve the imaging contrast performance, hydrogel-based microdroplets were designed for both US blood flow and PA imaging in this study. The microdroplets served as carriers for PA contrast agent solution in the innermost part while oil and hydrogel formed the inner and outer layers of the droplets. In vitro experiments firstly demonstrated the dual modality contrast effects of the microdroplets on US flow determination and PA imaging. In vivo experiments were then carried out in both healthy nude mice and nude mice with subcutaneous tumor to validate the contrast effects and to monitor the duration of contrast effects in animals. Using the dual-modality microdroplets, we were able to obtain distinct edges of tumor and blood flow mapping of the tumor microvascular with improved sensitivity up to 11.09 dB for PA and 6.69 dB for US flow. Besides, the in vivo evaluation with microdroplets showed US flow enhancement for more than 60 min. Therefore, the microdroplets are able to provide the contrast effects for both US flow and PA in a relative long duration and have potential to be applied in the tumor related diagnoses and studies.

Synthesis, characterization and in vivo evaluation of [62Zn]–benzo-δ-sultam complex as a possible pet imaging agent

2014 ◽  
Vol 28 (9) ◽  
pp. 880-890 ◽  
Author(s):  
Mehdi Ghandi ◽  
Shahzad Feizi ◽  
Farhood Ziaie ◽  
Yousef Fazaeli ◽  
Behrooz Notash
Keyword(s):  
Pet Imaging ◽  
Imaging Agent ◽  
In Vivo Evaluation

scholarly journals In Vivo Evaluation of Carborane Gadolinium-DTPA Complex as an MR Imaging Boron Carrier.

2000 ◽  
Vol 48 (7) ◽  
pp. 1034-1038 ◽  
Author(s):  
Hiroyuki NAKAMURA ◽  
Hiroshi FUKUDA ◽  
Frank GIRALD ◽  
Tooru KOBAYASHI ◽  
Jun'ichi HIRATSUKA ◽  
...  
Keyword(s):  
Mr Imaging ◽  
In Vivo Evaluation ◽  
Gadolinium Dtpa

scholarly journals In vivo MR and Fluorescence Dual-modality Imaging of Atherosclerosis Characteristics in Mice Using Profilin-1 Targeted Magnetic Nanoparticles

Theranostics ◽  
2016 ◽  
Vol 6 (2) ◽  
pp. 272-286 ◽  
Author(s):  
Yabin Wang ◽  
Jiangwei Chen ◽  
Bo Yang ◽  
Hongyu Qiao ◽  
Lei Gao ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Dual Modality ◽  
Dual Modality Imaging
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