Synthesis and in Vitro and in Vivo Evaluation of a Series of Dihydroisocoumarin Derivatives Conjugated with Fatty Acids, Alcohols, and Amines as Potential Anticancer Agents

2009 ◽  
Vol 20 (9) ◽  
pp. 1737-1751 ◽  
Author(s):  
Catherine A. Higgins ◽  
Zoica Delbederi ◽  
Kelly McGarel ◽  
Timothy Mills ◽  
Owen McGrath ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Anticancer Agents ◽  
In Vivo Evaluation

Effect of fatty acids on the transdermal delivery of donepezil: In vitro and in vivo evaluation

2012 ◽  
Vol 422 (1-2) ◽  
pp. 83-90 ◽  
Author(s):  
Joonho Choi ◽  
Min-Koo Choi ◽  
Saeho Chong ◽  
Suk-Jae Chung ◽  
Chang-Koo Shim ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Transdermal Delivery ◽  
In Vivo Evaluation

TISSUE CULTURE AND THE STUDY OF ANTICANCER AGENTS

1966 ◽  
Vol 44 (2) ◽  
pp. 339-343 ◽  
Author(s):  
Susan Tolnai
Keyword(s):  
Fatty Acids ◽  
Tumor Cells ◽  
Anticancer Agents ◽  
Antitumor Agents ◽  
Unsaturated Fatty Acids ◽  
Ascites Tumor ◽  
Mouse Tumors ◽  
Arachidonic Acids

In a quest for potential antitumor agents, more than 100 fatty acids and their derivatives were tested against transplantable mouse tumors with both in vivo and in vitro methods. Three compounds, 2,3-decenoic acid, linoleic acid, and linolenic acid, were found to arrest the growth of three types of ascites tumor cells, while 2-nonenoic, 10-undecenoic, oleic, and arachidonic acids were effective to a varying degree. The cytotoxic effects of these unsaturated fatty acids on monolayer cultures of Ehrlich ascites tumor cells and of normal mouse embryos were evaluated in experiments in which graded concentrations of the test materials incorporated in the culture medium were used.

In vitro and in vivo evaluation of organometallic gold(i) derivatives as anticancer agents

2016 ◽  
Vol 45 (6) ◽  
pp. 2462-2475 ◽  
Author(s):  
Elena García-Moreno ◽  
Alejandro Tomás ◽  
Elena Atrián-Blasco ◽  
Sonia Gascón ◽  
Eduardo Romanos ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Cell Line ◽  
Anticancer Agents ◽  
Cancer Cell Line ◽  
Colon Cancer Cell Line ◽  
Colon Cancer Cell ◽  
Water Soluble ◽  
In Vivo Evaluation

Alkyne gold(i) derivatives with the water soluble phosphanes PTA and DAPTA were described and their anticancer potential against the colon cancer cell line Caco-2 (PD7 and TC7 clones) was studied.

scholarly journals Copper complexes as prospective anticancer agents: in vitro and in vivo evaluation, selective targeting of cancer cells by DNA damage and S phase arrest

RSC Advances ◽  
2018 ◽  
Vol 8 (30) ◽  
pp. 16973-16990 ◽  
Author(s):  
Dharmasivam Mahendiran ◽  
Sethu Amuthakala ◽  
Nattamai S. P. Bhuvanesh ◽  
Raju Senthil Kumar ◽  
Aziz Kalilur Rahiman
Keyword(s):  
Dna Damage ◽  
Anticancer Agents ◽  
Copper Complexes ◽  
S Phase ◽  
In Vivo Evaluation ◽  
Phase Arrest ◽  
Selective Targeting ◽  
S Phase Arrest

The thiosemicarbazone-based copper(i) complexes causing S phase arrest and apoptosis involving the mitochondrial controlled pathway has been investigated.

In vitro and in vivo evaluation of the anti-inflammatory effects of Arzanol from Helichrysum italicum

Planta Medica ◽  
2010 ◽  
Vol 76 (12) ◽  
Author(s):  
J Bauer ◽  
F Dehm ◽  
A Koeberle ◽  
F Pollastro ◽  
G Appendino ◽  
...  
Keyword(s):  
In Vivo Evaluation ◽  
Anti Inflammatory

Short-Chain Fatty Acids Prevent Diabetic Nephropathy In Vivo and In Vitro

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 92-OR ◽  
Author(s):  
WEI HUANG ◽  
YONG XU ◽  
YOUHUA XU ◽  
LUPING ZHOU ◽  
CHENLIN GAO
Keyword(s):  
Fatty Acids ◽  
Diabetic Nephropathy ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Chain Fatty Acids
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