A New Optical and Nuclear Dual-Labeled Imaging Agent Targeting Interleukin 11 Receptor Alpha-Chain

2007 ◽  
Vol 18 (2) ◽  
pp. 397-402 ◽  
Author(s):  
Wei Wang ◽  
Shi Ke ◽  
Sunkuk Kwon ◽  
Sasidhar Yallampalli ◽  
Arlin G. Cameron ◽  
...  
Keyword(s):  
Imaging Agent ◽  
Receptor Alpha ◽  
Alpha Chain ◽  
Interleukin 11 ◽  
Receptor Alpha Chain

scholarly journals Cloning of rat interleukin 11 and interleukin 11 receptor alpha chain and analysis of their expression in rat uterus in the peri-implantation period

Reproduction ◽  
2001 ◽  
pp. 593-600 ◽  
Author(s):  
R Li ◽  
L Hartley ◽  
L Robb
Keyword(s):  
Rat Uterus ◽  
Rnase Protection ◽  
Receptor Alpha ◽  
Alpha Chain ◽  
Genes Encoding ◽  
Interleukin 11 ◽  
Implantation Period ◽  
Receptor Alpha Chain

Studies in mice have shown that interleukin 11 (IL-11) signalling is required for female fertility. In the absence of IL-11, decidualization is markedly retarded and implantation fails. IL-11 acts via a heterodimeric receptor composed of a ligand-specific receptor alpha chain (IL-11R alpha) and the signalling moiety gp130. This study reports the cloning of genes encoding rat IL-11 and IL-11R alpha. RNase protection was used to demonstrate that expression of IL-11 is upregulated in the rat uterus at the initiation of implantation at 5.5 days after mating. Expression of the genes encoding the two receptor components, IL11Ra and gp130, did not change throughout the peri-implantation period. In situ hybridization studies revealed that, as in mice, expression of IL-11 was high in the primary decidual zone at the time of the attachment reaction, whereas IL11Ra was expressed throughout primary and secondary decidua. Conservation of the temporal and spatial expression of IL-11 and IL-11R alpha in the uterus of the mouse and rat during the peri-implantation period will facilitate future studies investigating the role of IL-11 in fertility.

Characterization and expression analysis of the chicken interleukin-11 receptor alpha chain

2005 ◽  
Vol 29 (4) ◽  
pp. 349-359 ◽  
Author(s):  
Tsuyoshi Kawashima ◽  
Shintaro Hojyo ◽  
Norihisa Nishimichi ◽  
Masaharu Sato ◽  
Masayoshi Aosasa ◽  
...  
Keyword(s):  
Expression Analysis ◽  
Receptor Alpha ◽  
Alpha Chain ◽  
Interleukin 11 ◽  
Receptor Alpha Chain

Monoclonal antibodies against the human interleukin-11 receptor alpha-chain (IL-11Rα) and their use in studies of human mononuclear cells

2000 ◽  
Vol 241 (1-2) ◽  
pp. 43-59 ◽  
Author(s):  
Chrystel Blanc ◽  
Patricia Vusio ◽  
Karin Schleinkofer ◽  
Olivier Boisteau ◽  
Stefan Pflanz ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Mononuclear Cells ◽  
Receptor Alpha ◽  
Alpha Chain ◽  
Human Mononuclear Cells ◽  
Interleukin 11 ◽  
Receptor Alpha Chain

The gene for the human interleukin-11 receptor alpha chain locus is highly homologous to the murine gene and contains alternatively spliced first exons

1997 ◽  
Vol 29 (5) ◽  
pp. 753-766 ◽  
Author(s):  
Harshal H. Nandurkar ◽  
Lorraine Robb ◽  
Jillian K. Nicholl ◽  
Douglas J. Hilton ◽  
Grant R. Sutherland ◽  
...  
Keyword(s):  
Receptor Alpha ◽  
Alpha Chain ◽  
Chain Locus ◽  
Alternatively Spliced ◽  
Interleukin 11 ◽  
Receptor Alpha Chain

Functional expression of the interleukin-11 receptor alpha-chain in normal colonic epithelium and colon cancer

2005 ◽  
Vol 21 (6) ◽  
pp. 573-581 ◽  
Author(s):  
Nicole Deutscher ◽  
Frauke Bataille ◽  
Martin Hausmann ◽  
Stephan Kiessling ◽  
Gerhard Muller-Newen ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Functional Expression ◽  
Colonic Epithelium ◽  
Receptor Alpha ◽  
Alpha Chain ◽  
Normal Colonic Epithelium ◽  
Interleukin 11 ◽  
Receptor Alpha Chain

Interleukin-2 receptor alpha-chain (CD25) expression on leukaemic blasts is predictive for outcome and level of residual disease in AML

2009 ◽  
Vol 45 (9) ◽  
pp. 1692-1699 ◽  
Author(s):  
Monique Terwijn ◽  
Nicole Feller ◽  
Anna van Rhenen ◽  
Angèle Kelder ◽  
Guus Westra ◽  
...  
Keyword(s):  
Residual Disease ◽  
Interleukin 2 ◽  
Receptor Alpha ◽  
Alpha Chain ◽  
Cd25 Expression ◽  
Interleukin 2 Receptor ◽  
Receptor Alpha Chain

scholarly journals Dominant expression of a distinctive V14+ T-cell antigen receptor alpha chain in mice.

1991 ◽  
Vol 88 (17) ◽  
pp. 7518-7522 ◽  
Author(s):  
H. Koseki ◽  
H. Asano ◽  
T. Inaba ◽  
N. Miyashita ◽  
K. Moriwaki ◽  
...  
Keyword(s):  
T Cell ◽  
Antigen Receptor ◽  
T Cell Antigen Receptor ◽  
Cell Antigen Receptor ◽  
Receptor Alpha ◽  
Cell Antigen ◽  
Alpha Chain ◽  
Receptor Alpha Chain
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