Biodegradable, Endosome Disruptive, and Cationic Network-type Polymer as a Highly Efficient and Nontoxic Gene Delivery Carrier

2002 ◽  
Vol 13 (5) ◽  
pp. 952-957 ◽  
Author(s):  
Yong-beom Lim ◽  
Seon-mi Kim ◽  
Hearan Suh ◽  
Jong-sang Park
Keyword(s):  
Gene Delivery ◽  
Highly Efficient ◽  
Cationic Network ◽  
Network Type

scholarly journals Cyclen-Based Cationic Lipids for Highly Efficient Gene Delivery towards Tumor Cells

PLoS ONE ◽  
2011 ◽  
Vol 6 (8) ◽  
pp. e23134 ◽  
Author(s):  
Qing-Dong Huang ◽  
Guo-Xing Zhong ◽  
Yang Zhang ◽  
Jiang Ren ◽  
Yun Fu ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Tumor Cells ◽  
Cationic Lipids ◽  
Highly Efficient ◽  
Efficient Gene

Functionalized Superparamagnetic Nanoparticles for Highly-Efficient Gene Delivery

2013 ◽  
Vol 13 (2) ◽  
pp. 746-750
Author(s):  
Xiaowen Wang ◽  
Benke Chen ◽  
Xin Yang ◽  
Jieying Zhang ◽  
Linyun Zhao ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Superparamagnetic Nanoparticles ◽  
Highly Efficient ◽  
Efficient Gene

scholarly journals Biocleavable Polycationic Micelles as Highly Efficient Gene Delivery Vectors

2010 ◽  
Vol 5 (11) ◽  
pp. 1804-1811 ◽  
Author(s):  
Min Zhang ◽  
Ya-Nan Xue ◽  
Min Liu ◽  
Ren-Xi Zhuo ◽  
Shi-Wen Huang
Keyword(s):  
Gene Delivery ◽  
Highly Efficient ◽  
Gene Delivery Vectors ◽  
Efficient Gene

scholarly journals Local Gene Delivery System by Bubble Liposomes and Ultrasound Exposure into Joint Synovium

2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
Yoichi Negishi ◽  
Yuka Tsunoda ◽  
Yoko Endo-Takahashi ◽  
Yusuke Oda ◽  
Ryo Suzuki ◽  
...  
Keyword(s):  
Gene Expression ◽  
Gene Transfer ◽  
Gene Delivery ◽  
Delivery System ◽  
Imaging System ◽  
Effective Means ◽  
Gene Delivery System ◽  
Highly Efficient ◽  
Efficient Gene

Recently, we have developed novel polyethylene glycol modified liposomes (bubble liposomes; BL) entrapping an ultrasound (US) imaging gas, which can work as a gene delivery tool with US exposure. In this study, we investigated the usefulness of US-mediated gene transfer systems with BL into synoviocytes in vitro and joint synovium in vivo. Highly efficient gene transfer could be achieved in the cultured primary synoviocytes transfected with the combination of BL and US exposure, compared to treatment with plasmid DNA (pDNA) alone, pDNA plus BL, or pDNA plus US. When BL was injected into the knee joints of mice, and US exposure was applied transcutaneously to the injection site, highly efficient gene expression could be observed in the knee joint transfected with the combination of BL and US exposure, compared to treatment with pDNA alone, pDNA plus BL, or pDNA plus US. The localized and prolonged gene expression was also shown by an in vivo luciferase imaging system. Thus, this local gene delivery system into joint synovium using the combination of BL and US exposure may be an effective means for gene therapy in joint disorders.

Development of a Highly Efficient Purification Process for Recombinant Adenoviral Vectors for Oral Gene Delivery

1998 ◽  
Vol 3 (3) ◽  
pp. 365-372 ◽  
Author(s):  
Maria A. Croyle ◽  
Douglas J. Anderson ◽  
Blake J. Roessler ◽  
Gordon L. Amidon
Keyword(s):  
Gene Delivery ◽  
Adenoviral Vectors ◽  
Purification Process ◽  
Highly Efficient

Bioreducible Fluorinated Peptide Dendrimers Capable of Circumventing Various Physiological Barriers for Highly Efficient and Safe Gene Delivery

2016 ◽  
Vol 8 (9) ◽  
pp. 5821-5832 ◽  
Author(s):  
Xiaojun Cai ◽  
Rongrong Jin ◽  
Jiali Wang ◽  
Dong Yue ◽  
Qian Jiang ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Highly Efficient ◽  
Peptide Dendrimers

Wrinkled-Surface Mediated Reverse Transfection Platform for Highly Efficient, Addressable Gene Delivery

2016 ◽  
Vol 5 (16) ◽  
pp. 2025-2030 ◽  
Author(s):  
Hyunwoo Joo ◽  
Jisoo Shin ◽  
Seung-Woo Cho ◽  
Pilnam Kim
Keyword(s):  
Gene Delivery ◽  
Highly Efficient ◽  
Wrinkled Surface ◽  
Reverse Transfection
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