Chance and Necessity in the Selection of Nucleic Acid Catalysts

1996 ◽  
Vol 29 (2) ◽  
pp. 103-110 ◽  
Author(s):  
Jon R. Lorsch ◽  
Jack W. Szostak
Keyword(s):  
Nucleic Acid ◽  
Acid Catalysts ◽  
Selection Of

ChemInform Abstract: Chance and Necessity in the Selection of Nucleic Acid Catalysts

ChemInform ◽  
2010 ◽  
Vol 27 (23) ◽  
pp. no-no
Author(s):  
J. R. LORSCH ◽  
J. W. SZOSTAK
Keyword(s):  
Nucleic Acid ◽  
Acid Catalysts ◽  
Selection Of

Divergent synthesis of CF3-substituted polycyclic skeletons based on control of activation site of acid catalysts

2018 ◽  
Vol 54 (50) ◽  
pp. 6927-6930 ◽  
Author(s):  
Kazuma Yokoo ◽  
Keiji Mori
Keyword(s):  
Acid Catalysts ◽  
Precise Control ◽  
Selection Of ◽  
Activation Site

We report a divergent synthesis of CF3-substituted fused skeletons based on precise control of the activation site through the selection of acid catalysts.

In vitro selection of high-affinity nucleic acid ligands to parasite target molecules

2003 ◽  
Vol 33 (12) ◽  
pp. 1309-1317 ◽  
Author(s):  
H.Ulrich Göringer ◽  
Matthias Homann ◽  
Mihaela Lorger
Keyword(s):  
Nucleic Acid ◽  
In Vitro Selection ◽  
High Affinity ◽  
Target Molecules ◽  
Selection Of

scholarly journals A general approach to the design of allosteric, transcription factor-regulated DNAzymes

2015 ◽  
Vol 6 (7) ◽  
pp. 3692-3696 ◽  
Author(s):  
G. Adornetto ◽  
A. Porchetta ◽  
G. Palleschi ◽  
K. W. Plaxco ◽  
F. Ricci
Keyword(s):  
Transcription Factor ◽  
Nucleic Acid ◽  
Rational Design ◽  
Binding Proteins ◽  
General Strategy ◽  
Acid Catalysts ◽  
Nucleic Acid Binding ◽  
Nucleic Acid Binding Proteins

Here we explore a general strategy for the rational design of nucleic acid catalysts that can be allosterically activated by specific nucleic-acid binding proteins.

scholarly journals Selection of 2'-Deoxy-2'-Fluoroarabino Nucleic Acid (FANA) Aptamers that Bind HIV-1 Integrase with Picomolar Affinity

2019 ◽  
Author(s):  
Kevin M. Rose ◽  
Irani Alves Ferreira-Bravo ◽  
Min Li ◽  
Robert Craigie ◽  
Mark A Ditzler ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Hiv 1 ◽  
Selection Of
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