Compartmentalized Multilayer Hydrogel Formation Using a Stimulus-Responsive Self-Assembling Polysaccharide

2014 ◽  
Vol 6 (4) ◽  
pp. 2948-2957 ◽  
Author(s):  
Yuan Xiong ◽  
Kun Yan ◽  
William E. Bentley ◽  
Hongbing Deng ◽  
Yumin Du ◽  
...  
Keyword(s):  
Self Assembling ◽  
Stimulus Responsive ◽  
Hydrogel Formation

Supramolecular Hydrogel Formation in a Series of Self-Assembling Lipopeptides with Varying Lipid Chain Length

2017 ◽  
Vol 18 (7) ◽  
pp. 2013-2023 ◽  
Author(s):  
V. Castelletto ◽  
A. Kaur ◽  
R. M. Kowalczyk ◽  
I. W. Hamley ◽  
M. Reza ◽  
...  
Keyword(s):  
Chain Length ◽  
Supramolecular Hydrogel ◽  
Self Assembling ◽  
Hydrogel Formation ◽  
Lipid Chain

Monitoring the Early Stage Self-Assembly of Enzyme-Assisted Peptide Hydrogels

2013 ◽  
Vol 66 (5) ◽  
pp. 572 ◽  
Author(s):  
Richard J. Williams ◽  
James Gardiner ◽  
Anders B. Sorensen ◽  
Silvia Marchesan ◽  
Roger J. Mulder ◽  
...  
Keyword(s):  
1H Nmr ◽  
Self Assembly ◽  
Early Stage ◽  
The Self ◽  
Spectroscopic Techniques ◽  
Subsequent Formation ◽  
Self Assembling ◽  
Hydrogel Formation ◽  
Assembly Kinetics ◽  
Peptide Hydrogels

The early stages of the self-assembly of peptide hydrogels largely determine their final material properties. Here we discuss experimental methodologies for monitoring the self-assembly kinetics which underpin peptide hydrogel formation. The early stage assembly of an enzyme-catalysed Fmoc-trileucine based self-assembled hydrogel was examined using spectroscopic techniques (circular dichroism, CD, and solution NMR) as well as chromatographic (HPLC) and mechanical (rheology) techniques. Optimal conditions for enzyme-assisted hydrogel formation were identified and the kinetics examined. A lag time associated with the formation and accumulation of the self-assembling peptide monomer was observed and a minimum hydrogelator concentration required for gelation was identified. Subsequent formation of well defined nano- and microscale structures lead to self-supporting hydrogels at a range of substrate and enzyme concentrations. 1H NMR monitoring of the early self-assembly process revealed trends that were well in agreement with those identified using traditional methods (i.e. HPLC, CD, rheology) demonstrating 1H NMR spectroscopy can be used to non-invasively monitor the self-assembly of peptide hydrogels without damaging or perturbing the system.

scholarly journals Co-assembly and multicomponent hydrogel formation upon mixing nucleobase-containing peptides

Nanoscale ◽  
2021 ◽  
Author(s):  
Tristan Giraud ◽  
Sabine Bouguet-Bonnet ◽  
Marie-José Stébé ◽  
Lionel Richaudeau ◽  
Guillaume Pickaert ◽  
...  
Keyword(s):  
Soft Material ◽  
Self Assembling ◽  
Hydrogel Formation ◽  
Ordered Nanostructures

Peptide-based hydrogels are physical gels formed through specific supramolecular self-assembling processes, leading to ordered nanostructures which constitutes the water entrapping scaffold of the soft material. Thanks to the inherent properties...

scholarly journals Smart Supramolecular Self-Assembled Nanosystem: Stimulus-Responsive Hydrogen-Bonded Liquid Crystals

Nanomaterials ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 448
Author(s):  
Bing Liu ◽  
Tao Yang ◽  
Xin Mu ◽  
Zhijian Mai ◽  
Hao Li ◽  
...  
Keyword(s):  
Structure And Properties ◽  
Self Assembling ◽  
Shape Structure ◽  
Stimulus Responsive ◽  
Inorganic Nanomaterials ◽  
Non Covalent Interactions ◽  
Self Assembled ◽  
Immense Potential ◽  
Covalent Interactions ◽  
Hydrogen Bonded

In a liquid crystal (LC) state, specific orientations and alignments of LC molecules produce outstanding anisotropy in structure and properties, followed by diverse optoelectronic functions. Besides organic LC molecules, other nonclassical components, including inorganic nanomaterials, are capable of self-assembling into oriented supramolecular LC mesophases by non-covalent interactions. Particularly, huge differences in size, shape, structure and properties within these components gives LC supramolecules higher anisotropy and feasibility. Therefore, hydrogen bonds have been viewed as the best and the most common option for supramolecular LCs, owing to their high selectivity and directionality. In this review, we summarize the newest advances in self-assembled structure, stimulus-responsive capability and application of supramolecular hydrogen-bonded LC nanosystems, to provide novel and immense potential for advancing LC technology.

scholarly journals Development of an Amino Sugar-Based Supramolecular Hydrogelator with Reduction Responsiveness

2021 ◽  
Author(s):  
Sayuri L. Higashi ◽  
Masato Ikeda
Keyword(s):  
Molecular Weight ◽  
Molecular Design ◽  
Soft Materials ◽  
Amino Sugar ◽  
Low Molecular Weight ◽  
Stimuli Responsive ◽  
Supramolecular Hydrogel ◽  
Self Assembling ◽  
Hydrogel Formation

Stimuli-responsive supramolecular hydrogels are a newly emerging class of aqueous soft materials with a wide variety of bioapplications. Here we report a reduction-responsive supramolecular hydrogel constructed from a markedly simple low-molecular-weight hydrogelator, which is developed on the basis of modular molecular design containing a hydrophilic amino sugar and a reduction-responsive nitrophenyl group. The hydrogel formation ability differs significantly between glucosamine- and galactosamine-based self-assembling molecules, which are epimers at the C4 position, and only the glucosamine-based derivative can act as a hydrogelator.

scholarly journals Thiol- and Disulfide-Based Stimulus-Responsive Soft Materials and Self-Assembling Systems

Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3332
Author(s):  
Danielle M. Beaupre ◽  
Richard G. Weiss
Keyword(s):  
Biomedical Applications ◽  
Soft Materials ◽  
Self Healing ◽  
Self Assembling ◽  
Stimulus Responsive

Properties and applications of synthetic thiol- and disulfide-based materials, principally polymers, are reviewed. Emphasis is placed on soft and self-assembling materials in which interconversion of the thiol and disulfide groups initiates stimulus-responses and/or self-healing for biomedical and non-biomedical applications.

Anomalous Conformational Instability and Hydrogel Formation of a Cationic Class of Self-Assembling Oligopeptides

2010 ◽  
Vol 43 (18) ◽  
pp. 7800-7806 ◽  
Author(s):  
Thomas J. Measey ◽  
Reinhard Schweitzer-Stenner ◽  
Vijoya Sa ◽  
Konstantin Kornev
Keyword(s):  
Self Assembling ◽  
Hydrogel Formation

scholarly journals Development of an Amino Sugar-Based Supramolecular Hydrogelator with Reduction Responsiveness

2021 ◽  
Author(s):  
Sayuri L. Higashi ◽  
Masato Ikeda
Keyword(s):  
Molecular Weight ◽  
Molecular Design ◽  
Soft Materials ◽  
Amino Sugar ◽  
Low Molecular Weight ◽  
Stimuli Responsive ◽  
Supramolecular Hydrogel ◽  
Self Assembling ◽  
Hydrogel Formation

Stimuli-responsive supramolecular hydrogels are a newly emerging class of aqueous soft materials with a wide variety of bioapplications. Here we report a reduction-responsive supramolecular hydrogel constructed from a markedly simple low-molecular-weight hydrogelator, which is developed on the basis of modular molecular design containing a hydrophilic amino sugar and a reduction-responsive nitrophenyl group. The hydrogel formation ability differs significantly between glucosamine- and galactosamine-based self-assembling molecules, which are epimers at the C4 position, and only the glucosamine-based derivative can act as a hydrogelator.

Rational design of a photo-responsive UVR8-derived protein and a self-assembling peptide–protein conjugate for responsive hydrogel formation

Nanoscale ◽  
2015 ◽  
Vol 7 (40) ◽  
pp. 16666-16670 ◽  
Author(s):  
Xiaoli Zhang ◽  
Chunming Dong ◽  
Weiyun Huang ◽  
Huaimin Wang ◽  
Ling Wang ◽  
...  
Keyword(s):  
Rational Design ◽  
Self Assembling ◽  
Protein Conjugate ◽  
Hydrogel Formation
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