Superior Antibacterial Activity of Zinc Oxide/Graphene Oxide Composites Originating from High Zinc Concentration Localized around Bacteria

2014 ◽  
Vol 6 (4) ◽  
pp. 2791-2798 ◽  
Author(s):  
Yan-Wen Wang ◽  
Aoneng Cao ◽  
Yu Jiang ◽  
Xin Zhang ◽  
Jia-Hui Liu ◽  
...  
2019 ◽  
Vol 27 (8) ◽  
pp. 619-625 ◽  
Author(s):  
Yanzhen Huang ◽  
Xinling Hu ◽  
Yingjiang Qian ◽  
Shaofeng Huang ◽  
Dongxu Li

RSC Advances ◽  
2019 ◽  
Vol 9 (7) ◽  
pp. 3704-3714 ◽  
Author(s):  
Nagi El-Shafai ◽  
Mohamed E. El-Khouly ◽  
Maged El-Kemary ◽  
Mohamed Ramadan ◽  
Ibrahim Eldesoukey ◽  
...  

The fabrication, characterization, and antibacterial activity of novel nanocomposites based on graphene oxide (GO) nanosheets decorated with silver, titanium dioxide nanoparticles, and zinc oxide nanoflowers were examined.


2019 ◽  
Vol 20 (21) ◽  
pp. 5394 ◽  
Author(s):  
Yi-Huang Hsueh ◽  
Chien-Te Hsieh ◽  
Shu-Ting Chiu ◽  
Ping-Han Tsai ◽  
Chia-Ying Liu ◽  
...  

Graphene oxide (GO) composites with various metal nanoparticles (NPs) are attracting increasing interest owing to their broad scope in biomedical applications. Here, microwave-assisted chemical reduction was used to deposit nano-silver and zinc oxide NPs (Ag and ZnO NPs) on the surface of reduced GO (rGO) at the following weight percentages: 5.34% Ag/rGO, 7.49% Ag/rGO, 6.85% ZnO/rGO, 16.45% ZnO/rGO, 3.47/34.91% Ag/ZnO/rGO, and 7.08/15.28% Ag/ZnO/rGO. These materials were tested for antibacterial activity, and 3.47/34.91% Ag/ZnO/rGO and 7.08/15.28% Ag/ZnO/rGO exhibited better antibacterial activity than the other tested materials against the gram-negative bacterium Escherichia coli K12. At 1000 ppm, both these Ag/ZnO/rGO composites had better killing properties against both E. coli K12 and the gram-positive bacterium Staphylococcus aureus SA113 than Ag/rGO and ZnO/rGO did. RedoxSensor flow cytometry showed that 3.47/34.91% Ag/ZnO/rGO and 7.08/15.28% Ag/ZnO/rGO decreased reductase activity and affected membrane integrity in the bacteria. At 100 ppm, these two composites affected membrane integrity more in E. coli, while 7.08/15.28% Ag/ZnO/rGO considerably decreased reductase activity in S. aureus. Thus, the 3.47/34.91% and 7.08%/15.28% Ag/ZnO/rGO nanocomposites can be applied not only as antibacterial agents but also in a variety of biomedical materials such as sensors, photothermal therapy, drug delivery, and catalysis, in the future.


1974 ◽  
Vol 40 (5) ◽  
pp. 509-509 ◽  
Author(s):  
Sen Shyong JENG ◽  
Hsiu Wan Lo

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