Highly Uniform Hollow GdF3 Spheres: Controllable Synthesis, Tuned Luminescence, and Drug-Release Properties

2013 ◽  
Vol 5 (21) ◽  
pp. 10806-10818 ◽  
Author(s):  
Ruichan Lv ◽  
Shili Gai ◽  
Yunlu Dai ◽  
Na Niu ◽  
Fei He ◽  
...  
Keyword(s):  
Drug Release ◽  
Controllable Synthesis ◽  
Highly Uniform

Controllable synthesis of highly uniform cuboid-shape MOFs and their derivatives for lithium-ion battery and photocatalysis applications

2017 ◽  
Vol 322 ◽  
pp. 281-292 ◽  
Author(s):  
Jing Huang ◽  
Guozhao Fang ◽  
Kun Liu ◽  
Jiang Zhou ◽  
Xuekun Tang ◽  
...  
Keyword(s):  
Lithium Ion Battery ◽  
Lithium Ion ◽  
Controllable Synthesis ◽  
Highly Uniform

Controllable synthesis of highly uniform flower-like hierarchical carbon nanospheres and their application in high performance lithium–sulfur batteries

2017 ◽  
Vol 5 (13) ◽  
pp. 6245-6256 ◽  
Author(s):  
Daying Guo ◽  
Xi'an Chen ◽  
Huifang Wei ◽  
Menglan Liu ◽  
Feng Ding ◽  
...  
Keyword(s):  
High Performance ◽  
Sulfur Cathode ◽  
Controllable Synthesis ◽  
Carbon Nanospheres ◽  
Excellent Performance ◽  
Lithium Sulfur Batteries ◽  
Hierarchical Carbon ◽  
Highly Uniform ◽  
Lithium Sulfur

Highly uniform flower-like carbon nanospheres/sulfur cathode for Li–S battery delivers excellent performance.

Highly Uniform Hollow GdF3 Ellipsoids: Controllable Synthesis, Characterization and Up-Conversion Luminescence Properties

2018 ◽  
Vol 18 (8) ◽  
pp. 5822-5827 ◽  
Author(s):  
Yu Gao ◽  
Jinzhao Feng ◽  
Cheng Shi ◽  
Miaomiao Fan ◽  
Guiyan Zhao ◽  
...  
Keyword(s):  
Luminescence Properties ◽  
Controllable Synthesis ◽  
Highly Uniform

Multifunctional SiO2@Gd2O3:Yb/Tm Hollow Capsules: Controllable Synthesis and Drug Release Properties

2014 ◽  
Vol 53 (20) ◽  
pp. 10917-10927 ◽  
Author(s):  
Guixin Yang ◽  
Ruichan Lv ◽  
Shili Gai ◽  
Yunlu Dai ◽  
Fei He ◽  
...  
Keyword(s):  
Drug Release ◽  
Controllable Synthesis

Controllable Synthesis of Highly Uniform Nanosized HKUST-1 Crystals by Liquid–Solid–Solution Method

2019 ◽  
Vol 19 (2) ◽  
pp. 556-561 ◽  
Author(s):  
Xuechao Cai ◽  
Zhongxi Xie ◽  
Maolin Pang ◽  
Jun Lin
Keyword(s):  
Solid Solution ◽  
Solution Method ◽  
Controllable Synthesis ◽  
Highly Uniform

Formulation, Design and Development of Niosome Based Topical Gel for Skin Cancer

2017 ◽  
Vol 2 (3) ◽  
Keyword(s):  
Skin Cancer ◽  
Drug Release ◽  
Hemorrhagic Cystitis ◽  
The Body ◽  
Cancer Drug ◽  
Inversion Method ◽  
Body Parts ◽  
Basal Cells ◽  
Formulation Design ◽  
Topical Gel

Melanoma is the most dangerous type of skin cancer in which mostly damaged unpaired DNA starts mutating abnormally and staged an unprecedented proliferation of epithelial skin to form a malignant tumor. In epidemics of skin, pigment-forming melanocytes of basal cells start depleting and form uneven black or brown moles. Melanoma can further spread all over the body parts and could become hard to detect. In USA Melanoma kills an estimated 10,130 people annually. This challenge can be succumbed by using the certain anti-cancer drug. In this study design, cyclophosphamide were used as a model drug. But it has own limitation like mild to moderate use may cause severe cytopenia, hemorrhagic cystitis, neutropenia, alopecia and GI disturbance. This is a promising challenge, which is caused due to the increasing in plasma drug concentration above therapeutic level and due to no rate limiting steps involved in formulation design. In this study, we tried to modify drug release up to threefold and extended the release of drug by preparing and designing niosome based topical gel. In the presence of Dichloromethane, Span60 and cholesterol, the initial niosomes were prepared using vacuum evaporator. The optimum percentage drug entrapment efficacy, zeta potential, particle size was found to be 72.16%, 6.19mV, 1.67µm.Prepared niosomes were further characterized using TEM analyzer. The optimum batch of niosomes was selected and incorporated into topical gel preparation. Cold inversion method and Poloxamer -188 and HPMC as core polymers, were used to prepare cyclophosphamide niosome based topical gel. The formula was designed using Design expert 7.0.0 software and Box-Behnken Design model was selected. Almost all the evaluation parameters were studied and reported. The MTT shows good % cell growth inhibition by prepared niosome based gel against of A375 cell line. The drug release was extended up to 20th hours. Further as per ICH Q1A (R2), guideline 6 month stability studies were performed. The results were satisfactory and indicating a good formulation approach design was achieved for Melanoma treatment.

Effects of release modifier on Carvedilol release from Kollidon SR based matrix

2012 ◽  
Vol 1 (8) ◽  
pp. 186 ◽  
Author(s):  
Urmi Das ◽  
Mohammad Salim Hossain
Keyword(s):  
Drug Release ◽  
Sustained Release ◽  
Microcrystalline Cellulose ◽  
Matrix Tablets ◽  
Dissolution Time ◽  
Release Mechanism ◽  
Matrix Tablet ◽  
Weight Variation ◽  
The Matrix ◽  
Tablet Formulations

<p>Sustained release Carvedilol matrix tablets constituting Kollidon SR were developed in this study in an attempt to investigate the effect of release modifiers on the release profile of Carvedilol from matrix. Three matrix tablet formulations were prepared by direct compression of Kollidon SR in combination with release modifier (HPMC and Microcrystalline Cellulose) and magnesium stearate. Tablets containing only Kollidon SR with the active ingredient demonstrated a rapid rate of drug release. Incorporation of HPMC in the matrix tablet prolonged the release of drug but incorporation of Microcrystalline Cellulose showed superimposable release pattern with an initial burst effect as confirmed by mean dissolution time and Higuchi release rate data. After 7 hours of dissolution, Carvedilol release from the matrix systems were 91.42%, 83.41%, from formulation F1 and F2 respectively. Formulation F3 exhibited 100 % release at 4 hours. All the tablet formulations showed acceptable pharmaco-technical properties and complied with the in-house specifications for tablet weight variation, friability, hardness, thickness, and diameter. Prepared tablets also showed sustained release property for carvedilol. The drug release mechanism from the matrix tablets of F1 and F2 was found to be followed by Fickian and F3 by Non-Fickian mechanism.</p><p>DOI: <a href="http://dx.doi.org/10.3329/icpj.v1i8.11095">http://dx.doi.org/10.3329/icpj.v1i8.11095</a></p> <p>International Current Pharmaceutical Journal 2012, 1(8): 186-192</p>

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