Engineering of a Synthetic Metabolic Pathway for the Assimilation of (d)-Xylose into Value-Added Chemicals

2015 ◽  
Vol 5 (7) ◽  
pp. 607-618 ◽  
Author(s):  
Yvan Cam ◽  
Ceren Alkim ◽  
Debora Trichez ◽  
Vincent Trebosc ◽  
Amélie Vax ◽  
...  
Keyword(s):  
Metabolic Pathway ◽  
Value Added ◽  
Synthetic Metabolic Pathway

scholarly journals Construction of a synthetic metabolic pathway for biosynthesis of the non-natural methionine precursor 2,4-dihydroxybutyric acid

2017 ◽  
Vol 8 (1) ◽  
Author(s):  
Thomas Walther ◽  
Christopher M. Topham ◽  
Romain Irague ◽  
Clément Auriol ◽  
Audrey Baylac ◽  
...  
Keyword(s):  
Metabolic Pathway ◽  
Synthetic Metabolic Pathway

scholarly journals Construction of a synthetic metabolic pathway for the production of 2,4-dihydroxybutyric acid from homoserine

2018 ◽  
Vol 45 ◽  
pp. 237-245 ◽  
Author(s):  
Thomas Walther ◽  
Florence Calvayrac ◽  
Yoann Malbert ◽  
Ceren Alkim ◽  
Clémentine Dressaire ◽  
...  
Keyword(s):  
Metabolic Pathway ◽  
Synthetic Metabolic Pathway

scholarly journals Horizontal Transfer of a Synthetic Metabolic Pathway between Plant Species

2017 ◽  
Vol 27 (19) ◽  
pp. 3034-3041.e3 ◽  
Author(s):  
Yinghong Lu ◽  
Sandra Stegemann ◽  
Shreya Agrawal ◽  
Daniel Karcher ◽  
Stephanie Ruf ◽  
...  
Keyword(s):  
Plant Species ◽  
Metabolic Pathway ◽  
Horizontal Transfer ◽  
Synthetic Metabolic Pathway

scholarly journals Synthetic Metabolic Pathway for the Production of 1-Alkenes from Lignin-derived Molecules

2018 ◽  
Author(s):  
Jin Luo ◽  
Tapio Lehtinen ◽  
Elena Efimova ◽  
Ville Santala ◽  
Suvi Santala
Keyword(s):  
Value Added ◽  
Downstream Processing ◽  
Production Costs ◽  
Acid Decarboxylase ◽  
Acinetobacter Baylyi ◽  
Adaptive Laboratory Evolution ◽  
Tolerant Strain ◽  
In The Wild ◽  
Alkene Synthesis ◽  
Synthetic Metabolic Pathway

AbstractIntegration of synthetic metabolic pathways to catabolically diverse chassis provides new opportunities for sustainable production. One attractive scenario is the use of abundant waste material to produce readily collectable product, minimizing production costs. Towards that end, we established the production of semivolatile medium-chain α-olefins from lignin-derived monomers: we constructed 1-undecene synthesis pathway inAcinetobacter baylyiADP1 using ferulate as the sole carbon source. In order to overcome the toxicity of ferulate, we first applied adaptive laboratory evolution, resulting in a highly ferulate-tolerant strain. Next, we demonstrated the 1-undecene production from glucose by heterologously expressing a fatty acid decarboxylase UndA and a thioesterase ‘TesA in the wild type strain. Finally, we constructed the alkene synthesis pathway in the ferulate-tolerant strain. We were able to produce 1-undecene from ferulate and collect the product from the culture headspace without downstream processing. This study demonstrates the potential of bacterial lignin upgradation into value-added products.

Constructing a synthetic metabolic pathway inEscherichia colito produce the enantiomerically pure (R, R)-2,3-butanediol

2015 ◽  
Vol 112 (5) ◽  
pp. 1056-1059 ◽  
Author(s):  
Xiao-Jun Ji ◽  
Lu-Gang Liu ◽  
Meng-Qiu Shen ◽  
Zhi-Kui Nie ◽  
Ying-Jia Tong ◽  
...  
Keyword(s):  
Metabolic Pathway ◽  
Enantiomerically Pure ◽  
Synthetic Metabolic Pathway

A Synthetic Metabolic Pathway for Production of the Platform Chemical Isobutyric Acid

ChemSusChem ◽  
2011 ◽  
Vol 4 (8) ◽  
pp. 1068-1070 ◽  
Author(s):  
Kechun Zhang ◽  
Adam P. Woodruff ◽  
Mingyong Xiong ◽  
Jun Zhou ◽  
Yogesh K. Dhande
Keyword(s):  
Metabolic Pathway ◽  
Isobutyric Acid ◽  
Platform Chemical ◽  
Synthetic Metabolic Pathway
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