1,10-Phenanthroline Monohydrate

2017 ◽  
Keyword(s):  
Phenanthroline Monohydrate

scholarly journals Synthesis and Heme Polymerization Inhibitory Activity (HPIA) Assay of Antiplasmodium of (1)-N-(3,4-Dimethoxybenzyl)-1,10-Phenanthrolinium Bromide from Vanillin

2014 ◽  
Vol 14 (1) ◽  
pp. 1-6
Author(s):  
Dhina Fitriastuti ◽  
Muhammad Idham Darussalam Mardjan ◽  
Jumina Jumina ◽  
Mustofa Mustofa
Keyword(s):  
Melting Point ◽  
Sodium Borohydride ◽  
Inhibitory Activity ◽  
Veratryl Alcohol ◽  
Activity Assay ◽  
Light Yellow ◽  
Grinding Method ◽  
Methylation Product ◽  
Ft Ir ◽  
Phenanthroline Monohydrate

The synthesis of (1)-N-(3,4-dimethoxy-benzyl)-1,10-phenanthrolinium bromide had been conducted from vanillin. Heme polymerization inhibitory activity assay of the synthesized antiplasmodium has also been carried out. The first step of reaction was methylation of vanillin using dimethylsulfate and NaOH. The mixture was refluxed for 2 h to yield veratraldehyde in the form of light yellow solid (79% yield). Methylation product was reduced using sodium borohydride (NaBH4) with grinding method and yielded veratryl alcohol in the form of yellow liquid (98% yield). Veratryl alcohol was brominated using PBr3 to yield yellowish black liquid (85% yield). The final step was benzylation of 1,10-phenanthroline monohydrate with the synthesized veratryl bromide under reflux condition in acetone for 14 h to afford (1)-N-(3,4-dimethoxy-benzyl)-1,10-phenanthrolinium bromide (84%) as yellow solid with melting point of 166-177 °C. The structures of products were characterized by FT-IR, GC-MS and 1H-NMR spectrometers. The results of heme polymerization inhibitory activity assay of (1)-N-(3,4-dimethoxybenzyl)-1,10-phenanthrolinium bromide showed that it had IC50 HPIA of 3.63 mM, while chloroquine had IC50 of4.37 mM. These results indicated that (1)-N-(3,4-dimethoxybenzyl)-1,10-phenanthrolinium bromide was more potential antiplasmodium than chloroquine.

Enhanced Fluorescence Emission of Bonding Type Rare Earth Complexes Eu(MAA)3Phen

2017 ◽  
Vol 898 ◽  
pp. 1839-1843 ◽  
Author(s):  
Bin Wang ◽  
Lu Lu Xiao ◽  
Heng Xue Xiang ◽  
Bin Sun ◽  
Mei Fang Zhu
Keyword(s):  
Rare Earth ◽  
Fluorescence Spectra ◽  
Central Atom ◽  
Fluorescence Emission ◽  
Ion Concentration ◽  
Luminescent Materials ◽  
Enhanced Fluorescence ◽  
Rare Earth Ion ◽  
Element Analysis ◽  
Phenanthroline Monohydrate

Rare earth fluorescent complexes monomer with activated double bonds was synthesized by using Eu as the central atom, Methacrylic acid and 1, 10-Phenanthroline monohydrate as ligand. The structure of resultant Eu (MAA)3Phen was determined by infrared spectrum, ultraviolet spectrum and element analysis, and the fluorescence property of the complexes was tested by fluorescence spectra and fluorescence microscopy. Compared with conventional luminescent materials, this resultant complexes show greater fluorescence intensity. The analysis has revealed that with the increase of rare earth ion concentration from 4×10-5mol·L-1 to 4×10-3mol·L-1, the fluorescence quenching phenomenon appeared in the complexes solution.

Synthesis, structure, and DNA-binding study of a novel Zn (II) complex with fleroxacin and 1,10-phenanthroline monohydrate

2019 ◽  
Vol 103 ◽  
pp. 6-11
Author(s):  
Yujie Zhu ◽  
Xinnuo Xiong ◽  
Zili Suo ◽  
Peixiao Tang ◽  
Qiaomei Sun ◽  
...  
Keyword(s):  
Dna Binding ◽  
Binding Study ◽  
Phenanthroline Monohydrate

Synthesis of efficient Co and N co-doped carbon catalysts with high surface areas for selective oxidation of ethylbenzene

2018 ◽  
Vol 42 (15) ◽  
pp. 12677-12683
Author(s):  
Yuan Li ◽  
Shanshan Jie ◽  
Kun Li ◽  
Zhigang Liu
Keyword(s):  
Selective Oxidation ◽  
High Surface ◽  
Cobalt Nitrate ◽  
Acid Etching ◽  
Pore Former ◽  
Surface Areas ◽  
Oxidation Of Ethylbenzene ◽  
Phenanthroline Monohydrate ◽  
Carbon Catalysts ◽  
Co Doped

In this manuscript, Co and N co-doped carbon catalysts with high surface areas were prepared via the pyrolysis of cobalt nitrate and 1,10-phenanthroline monohydrate, using Mg(OH)2 as a pore former, followed by acid etching.

Synthesis and electrical properties of CuBr2 complexes with 1,10-phenanthroline monohydrate

2008 ◽  
Vol 62 (3) ◽  
Author(s):  
Sülin Taşcıoǧlu ◽  
Esra Kakı ◽  
Mehmet Arı
Keyword(s):  
Electrical Properties ◽  
Electronic Spectroscopy ◽  
Ammonia Solution ◽  
Complex Ii ◽  
Molar Ratios ◽  
Trigonal Bipyramidal ◽  
Structural And Electrical Properties ◽  
Distorted Trigonal Bipyramidal Coordination ◽  
Phenanthroline Monohydrate ◽  
Hydrogen Bondings

AbstractUsing 1,10-phenanthroline monohydrate and CuBr2 in molar ratios of 1:1 and 2:1, in CH3OH/H2O (ϕr = 1:1), the complexes [(phen)CuBr2]2, (I), and {[(phen)2CuBr]Br·H2O}, (II), have been prepared. The hydrogen bondings and aqua bridges between coordinated and noncoordinated bromides of II have been observed by XRD. Complex II has a triclinic crystal structure with distorted trigonal bipyramidal coordination geometry. Possibilities of ligand exchange with hydroxide or ammonia have been examined in both complexes. While the mononuclear complex II is stable in a refluxed ammonia solution and the complex {[phen)2CuBr]Br·3H2O}, (IV), trihydrate of II, is obtained; the binuclear complex I reacts with the ammonia solution to replace one of its bromides in the subunits with hydroxide to give {[(phen)2Cu2Br2(OH)2]·4H2O}, (III). Structural and electrical properties of the complexes have been investigated by elemental analysis, vibrational and electronic spectroscopy, mass spectrometry, TGA, XRD and the four-point probe method. The temperature coefficients of resistivity and the activation energies of the complexes have also been obtained. All complexes behave as intrinsic semiconductor in the temperature range of 310–440 K.

Two Hydroxo Bridged Dinuclear Lanthanide Phen Complexes: [Ln2(phen)4(H2O)4(OH)2](phen)2(NO3)4 with Ln = Tm, Yb

2002 ◽  
Vol 57 (6) ◽  
pp. 625-630 ◽  
Author(s):  
Dan-Yi Wei ◽  
Yue-Qing Zheng ◽  
Jian-Li Lin
Keyword(s):  
Magnetic Moment ◽  
Room Temperature ◽  
Complex Cation ◽  
Magnetic Ordering ◽  
Oh Groups ◽  
Π Stacking ◽  
Lanthanide Atoms ◽  
Phenanthroline Monohydrate ◽  
Experimental Magnetic Moment ◽  
Hydrogen Bonded

AbstractTwo isostructural hydroxo bridged dinuclear lanthanide phen complexes of general composition [Ln2(phen)4(H2O)4(OH)2](phen)2(NO3)4 with Ln = Tm (1), Yb (2) were prepared by reactions of the corresponding lanthanide nitrate and phenanthroline monohydrate in CH3OH/H2O at pH = 5.5. They crystallize in the triclinic space group P1̄ (no. 2) with the cell dimensions: a = 11.233(1), b = 11.456(1), c = 14.011(2) Å , α = 93.91(1)°, β = 98.20(1)°, γ = 108.21(1)°, V = 1683.0(3)Å3, Z = 1 for 1 and a = 11.236(1), b = 11.480(2), c = 13.986(2)Å , α = 93.91(1)°, β = 98.17(1)°, γ = 108.33(1)°, V = 1682.9(3) Å3, Z = 1 for 2. The crystal structures are composed of the hydroxo bridged dinuclear [Ln2(phen)4(H2O)4(OH)4]4+ complex cations, hydrogen bonded NO3- anions and π-π stacking (phen)2 dimers. The lanthanide atoms are each surrounded by two phen ligands, two H2O molecules and two μ-OH groups to complete a tetragonal antiprismatic LnN4O4 coordination. Via two common μ-OH groups, two neighboring tetragonal antiprisms are condensed to form a centrosymmetric dinuclear [Ln2(phen)4(H2O)4(OH)4]4+ complex cation. The complex cations and (phen)2 dimers are assembled via π-π stacking interactions and hydrogen bondings into 2D layers parallel to (101̄), between which the hydrogen bonded NO3- anions are sandwiched. The Tm compound shows paramagnetic behavior with an experimental magnetic moment of 7.51 μB at room temperature. No magnetic ordering is evident down to 5 K. Over the temperature range 70 - 300 K, the Yb compound obeys the Curie-Weiss law with an experimental magnetic moment of 4.32 μB at room temperature and shows weak ferrimagnetic behavior at low temperature.

Copper-Catalyzed Cleavage of Unstrained C–C Bonds for the Synthesis of 1-Acyloxy-2,2,6,6-tetramethylpiperidines from Cyclic or Acyclic Ketones

Synlett ◽  
2017 ◽  
Vol 28 (16) ◽  
pp. 2163-2168 ◽  
Author(s):  
Wang Zhou ◽  
Qijian Jiang ◽  
Luo Yang
Keyword(s):  
Bond Cleavage ◽  
New Strategy ◽  
Phenanthroline Monohydrate ◽  
Acyclic Ketones

A copper-catalyzed approach for the synthesis of 1-acyloxy-2,2,6,6-tetramethylpiperidines through the C–C bond cleavage of cyclic or acyclic ketones was developed. In this chemistry, a combination of CuCl2·2H2O, 1,10-phenanthroline monohydrate, and aniline was crucial for the formation of the desired products by the reaction of ketones with TEMPO. This research provides a new strategy for the further transformation of α-aryl cyclic or acyclic ketones.

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