scholarly journals Probing Nanoparticle–Cell Interaction Using Micro-Raman Spectroscopy: Silver and Gold Nanoparticle-Induced Stress Effects on Optically Trapped Live Red Blood Cells

ACS Omega ◽  
2020 ◽  
Vol 5 (3) ◽  
pp. 1439-1447 ◽  
Author(s):  
Surekha Barkur ◽  
Jijo Lukose ◽  
Santhosh Chidangil
Keyword(s):  
Raman Spectroscopy ◽  
Red Blood Cells ◽  
Gold Nanoparticle ◽  
Blood Cells ◽  
Cell Interaction ◽  
Stress Effects ◽  
Micro Raman Spectroscopy ◽  
Induced Stress ◽  
Optically Trapped

scholarly journals Normal saline-induced deoxygenation of red blood cells probed by optical tweezers combined with the micro-Raman technique

RSC Advances ◽  
2019 ◽  
Vol 9 (14) ◽  
pp. 7878-7884 ◽  
Author(s):  
Jijo Lukose ◽  
Mithun N ◽  
Ganesh Mohan ◽  
Shamee Shastry ◽  
Santhosh Chidangil
Keyword(s):  
Raman Spectroscopy ◽  
Blood Cell ◽  
Red Blood Cells ◽  
Optical Tweezers ◽  
Red Blood Cell ◽  
Normal Saline ◽  
Blood Cells ◽  
Micro Raman Spectroscopy ◽  
Optically Trapped

Micro-Raman spectroscopy of optically trapped live red blood cell demonstrates normal saline induced deoxygenation.

scholarly journals Correction: Micro-Raman Spectroscopy of Silver Nanoparticle Induced Stress on Optically-Trapped Stem Cells

PLoS ONE ◽  
2012 ◽  
Vol 7 (7) ◽  
Author(s):  
Aseefhali Bankapur ◽  
R. Sagar Krishnamurthy ◽  
Elsa Zachariah ◽  
Chidangil Santhosh ◽  
Basavaraj Chougule ◽  
...  
Keyword(s):  
Stem Cells ◽  
Raman Spectroscopy ◽  
Silver Nanoparticle ◽  
Micro Raman Spectroscopy ◽  
Induced Stress ◽  
Optically Trapped

Red blood cells under externally induced stressors probed by micro-Raman spectroscopy

2022 ◽  
pp. 141-165
Author(s):  
Jijo Lukose ◽  
Shamee Shastry ◽  
Ganesh Mohan ◽  
Santhosh Chidangil
Keyword(s):  
Raman Spectroscopy ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Micro Raman Spectroscopy

scholarly journals Micro-Raman Spectroscopy of Silver Nanoparticle Induced Stress on Optically-Trapped Stem Cells

PLoS ONE ◽  
2012 ◽  
Vol 7 (4) ◽  
pp. e35075 ◽  
Author(s):  
Aseefhali Bankapur ◽  
R. Sagar Krishnamurthy ◽  
Elsa Zachariah ◽  
Chidangil Santhosh ◽  
Basavaraj Chougule ◽  
...  
Keyword(s):  
Stem Cells ◽  
Raman Spectroscopy ◽  
Silver Nanoparticle ◽  
Micro Raman Spectroscopy ◽  
Induced Stress ◽  
Optically Trapped

Red Blood Cells in Patients with Arrhythmias Using Optical Tweezers Raman Spectroscopy

2011 ◽  
Vol 48 (2) ◽  
pp. 021701
Author(s):  
吴智辉 Wu Zhihui ◽  
莫华 Mo Hua ◽  
黄代政 Huang Daizheng ◽  
陈朝旺 Chen Chaowang
Keyword(s):  
Raman Spectroscopy ◽  
Red Blood Cells ◽  
Optical Tweezers ◽  
Blood Cells

Variation of Local Mechanical Stress During the Different Processing Steps of Ic-Isolation: a Micro-Raman Spectroscopy Study

1993 ◽  
Vol 308 ◽  
Author(s):  
Ingrid De Wolf ◽  
Herman E. Maes ◽  
Hans Norström
Keyword(s):  
Raman Spectroscopy ◽  
Integrated Circuits ◽  
Mechanical Stress ◽  
Local Variation ◽  
Micro Raman Spectroscopy ◽  
Induced Stress ◽  
Last Stage ◽  
Edge Force ◽  
Field Oxide ◽  
Processing Steps

ABSTRACTLocal mechanical stress introduced in the silicon substrate during the successive steps of poly-buffered local isolation of MOS integrated circuits is studied with micro-Raman spectroscopy. It is shown that the magnitude and the local variation of the stress is highly affected by the different processing steps. After deposition of the nitride mask, the stress can be described as caused by an edge-force. Field oxidation reduces the mask-induced stress but introduces thermal stress from the field oxide. Also the formation of the bird's beak gives rise to additional local tensile stress, especially at the tip of the bird's beak. Removal of the nitride mask results in a partial relaxation: the stress caused by the bird's beak relaxes. In this last stage of the isolation process, the stress image is mostly determined by the field oxide.

Micro-Raman spectroscopy in medicine

2019 ◽  
Vol 4 (10) ◽  
Author(s):  
Christoph Krafft ◽  
Jürgen Popp
Keyword(s):  
Raman Spectroscopy ◽  
Tissue Characterization ◽  
Point Of Care ◽  
Cell Metabolism ◽  
Single Cells ◽  
Cell Interaction ◽  
Diagnostic Tools ◽  
Clinical Tool ◽  
Micro Raman Spectroscopy ◽  
Molecular Specificity

Abstract A potential role of optical technologies in medicine including micro-Raman spectroscopy is diagnosis of bacteria, cells and tissues which is covered in this chapter. The main advantage of Raman-based methods to complement and augment diagnostic tools is that unsurpassed molecular specificity is achieved without labels and in a nondestructive way. Principles and applications of micro-Raman spectroscopy in the context of medicine will be described. First, Raman spectra of biomolecules representing proteins, nucleic acids, lipids and carbohydrates are introduced. Second, microbial applications are summarized with the focus on typing on species and strain level, detection of infections, antibiotic resistance and biofilms. Third, cytological applications are presented to classify single cells and study cell metabolism and drug–cell interaction. Fourth, applications to tissue characterization start with discussion of lateral resolution for Raman imaging followed by Raman-based detection of pathologies and combination with other modalities. Finally, an outlook is given to translate micro-Raman spectroscopy as a clinical tool to solve unmet needs in point-of-care applications and personalized treatment of diseases.

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