scholarly journals Sustainable Synthetic Approach for (Pyrazol-4-ylidene)pyridines By Metal Catalyst-Free Aerobic C(sp2)–C(sp3) Coupling Reactions between 1-Amino-2-imino-pyridines and 1-Aryl-5-pyrazolones

ACS Omega ◽  
2019 ◽  
Vol 4 (7) ◽  
pp. 11701-11711 ◽  
Author(s):  
Hamada Mohamed Ibrahim ◽  
Haider Behbehani
Keyword(s):  
Metal Catalyst ◽  
Synthetic Approach ◽  
Coupling Reactions ◽  
Catalyst Free

Metal catalyst free one-pot synthesis of 2-arylbenzimidazoles from α-aroylketene dithioacetals

RSC Advances ◽  
2014 ◽  
Vol 4 (23) ◽  
pp. 12028-12036 ◽  
Author(s):  
Pandi Dhanalakshmi ◽  
Solaimalai Thimmarayaperumal ◽  
Sivakumar Shanmugam
Keyword(s):  
Metal Catalyst ◽  
Synthetic Approach ◽  
One Pot ◽  
Catalyst Free ◽  
One Pot Synthesis

An efficient green synthetic approach has been developed towards the synthesis of 2-aryl substituted benzimidazoles 4 from α-aroylketene dithioacetals (AKDTAs) 1 and phenylenediamine (OPD) 2.

scholarly journals The Application of Nafion Metal Catalyst Free Carbon Nanotube Modified Gold Electrode: Voltammetric Zinc Detection in Serum

2013 ◽  
pp. n/a-n/a ◽  
Author(s):  
Wei Yue ◽  
Adam Bange ◽  
Bill L. Riehl ◽  
Jay M. Johnson ◽  
Ian Papautsky ◽  
...  
Keyword(s):  
Carbon Nanotube ◽  
Gold Electrode ◽  
Free Carbon ◽  
Metal Catalyst ◽  
Catalyst Free ◽  
Zinc Detection

scholarly journals Transition Metal Catalyst‐Free, Base‐Promoted 1,2‐Additions of Polyfluorophenylboronates to Aldehydes and Ketones

2021 ◽  
Author(s):  
Zhiqiang Liu ◽  
Goutam Kumar Kole ◽  
Yudha P. Budiman ◽  
Ya-Ming Tian ◽  
Alexandra Friedrich ◽  
...  
Keyword(s):  
Transition Metal ◽  
Metal Catalyst ◽  
Free Base ◽  
Transition Metal Catalyst ◽  
Catalyst Free ◽  
Aldehydes And Ketones

Unprecedented Copper(II) Coordination Induced Nucleophilic Cleavage of Quinoxaline Heterocycle: Structural and Computational Studies

CrystEngComm ◽  
2021 ◽  
Author(s):  
Bhaskar Biswas ◽  
Nilaj Banerjee ◽  
Mayank Joshi ◽  
Stevan Armaković ◽  
Sanja J Armaković ◽  
...  
Keyword(s):  
Synthetic Approach ◽  
Computational Studies ◽  
Quinoxaline Derivative ◽  
Catalyst Free ◽  
Nucleophilic Cleavage

A straightforward catalyst-free synthetic approach has been developed for the synthesis of quinoxaline derivative, 4-phenyl-4-(pyridin-2-yl)-4,5-dihydropyrrolo[1,2-a]quinoxaline (L) by the reaction of 2-benzoyl pyridine and pyrrole-1-anillin in ethanol. The L in presence...

Formation of Csp2-N bond under metal-catalyst-free conditions for the synthesis of pyridopyrazoloquinazoline derivatives

2015 ◽  
Vol 147 (4) ◽  
pp. 775-782 ◽  
Author(s):  
Chao Li ◽  
Wen-Qiang Lu ◽  
Mei-Mei Zhang ◽  
Xiang-Shan Wang
Keyword(s):  
Metal Catalyst ◽  
Catalyst Free

scholarly journals Synthetic Approach toward α-Aminomethyl-γ-butyrolactones from β-Lactam Synthons Elaborated by SmI2-mediated Reductive Coupling Reactions

2013 ◽  
Vol 8 (7) ◽  
pp. 1934578X1300800
Author(s):  
Masaki Takahashi ◽  
Takahiro Sudo ◽  
Yusuke Murata ◽  
Tetsuya Sengoku ◽  
Hidemi Yoda
Keyword(s):  
Ring Opening ◽  
Coupling Reaction ◽  
Synthetic Approach ◽  
Coupling Reactions ◽  
Reductive Coupling ◽  
Important Class

A simple and straightforward synthetic approach was developed to access a biologically important class of α-aminomethyl-γ-butyrolactones via a β-lactam synthon strategy involving successive ring-opening and lactonization processes from α-hydroxyethyl-substituted β-lactams that were elaborated by SmI2-mediated reductive coupling reaction.

Diversity-Oriented Synthesis via Catalyst-Free Addition of Ketones to [e]-Fused 1H-Pyrrole-2,3-diones

Synthesis ◽  
2018 ◽  
Vol 50 (24) ◽  
pp. 4897-4904 ◽  
Author(s):  
Ekaterina Stepanova ◽  
Andrey Maslivets ◽  
Svetlana Kasatkina ◽  
Maksim Dmitriev
Keyword(s):  
Intramolecular Cyclization ◽  
Aromatic Hydrocarbons ◽  
Michael Addition ◽  
Aldol Reaction ◽  
Synthetic Approach ◽  
Reaction Conditions ◽  
Diversity Oriented Synthesis ◽  
Catalyst Free ◽  
Solvent Free Conditions ◽  
Reaction Proceeds

A facile synthetic approach towards two distinct pyrrole-based heterocyclic scaffolds has been developed by the interaction of 1H-pyrrole-2,3-diones fused at the [e]-side to a 1,4-benzoxazin-2-one or quinoxalin-2(1H)-one moiety with ketones. The described interaction proceeds either as an aldol reaction or as a Michael addition/intramolecular cyclization depending on the reaction conditions. The disclosed aldol reaction proceeds with good diastereoselectivity under catalyst-free conditions when the reaction is carried out in aromatic hydrocarbons. Products of the cascade Michael addition/intramolecular cyclization reaction are predominantly formed under catalyst-free and solvent-free conditions. The proposed strategy provides facile access to pharmaceutically interesting pyrrole-based polyheterocycles.

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