scholarly journals In Vivo Toxicity Study of Engineered Lipid Microbubbles in Rodents

ACS Omega ◽  
2019 ◽  
Vol 4 (3) ◽  
pp. 5526-5533 ◽  
Author(s):  
Gaio Paradossi ◽  
Letizia Oddo ◽  
Barbara Cerroni ◽  
Carmit Ben-Harush ◽  
Eti Ariel ◽  
...  
Keyword(s):  
Toxicity Study ◽  
In Vivo Toxicity

scholarly journals Development and Characterization of siRNA Lipoplexes: Effect of Different Lipids, In Vitro Evaluation in Cancerous Cell Lines and In Vivo Toxicity Study

2014 ◽  
Vol 15 (6) ◽  
pp. 1630-1643 ◽  
Author(s):  
Nirav Khatri ◽  
Dipesh Baradia ◽  
Imran Vhora ◽  
Mohan Rathi ◽  
Ambikanandan Misra
Keyword(s):  
Cell Lines ◽  
Toxicity Study ◽  
In Vitro Evaluation ◽  
In Vivo Toxicity ◽  
Cancerous Cell

scholarly journals Preparation and in vivo toxicity study of solid lipid microparticles as carrier for pulmonary administration

2004 ◽  
Vol 5 (2) ◽  
pp. 17-23 ◽  
Author(s):  
Vanna Sanna ◽  
Nathalie Kirschvink ◽  
Pascal Gustin ◽  
Elisabeta Gavini ◽  
Isabelle Roland ◽  
...  
Keyword(s):  
Toxicity Study ◽  
In Vivo Toxicity ◽  
Pulmonary Administration ◽  
Solid Lipid ◽  
Solid Lipid Microparticles ◽  
Lipid Microparticles

scholarly journals In vivo Toxicity Study and Antifilarial Activity of Four Plants from Nord-Cameroon

2017 ◽  
Vol 19 (3) ◽  
pp. 1-12 ◽  
Author(s):  
Ndjonka Dieudonné ◽  
Ayouba Mouraba ◽  
Ahamat Abakar ◽  
Djafsia Boursou ◽  
Ndouwe Honore
Keyword(s):  
Toxicity Study ◽  
In Vivo Toxicity ◽  
Antifilarial Activity

scholarly journals In Vivo Toxicity Study of Ethanolic Extracts of Evolvulus alsinoides & Centella asiatica in Swiss Albino Mice

2019 ◽  
Vol 7 (7) ◽  
pp. 1071-1076
Author(s):  
Mukesh Kumar Yadav ◽  
Santosh Kumar Singh ◽  
Manish Singh ◽  
Shashank Shekhar Mishra ◽  
Anurag Kumar Singh ◽  
...  
Keyword(s):  
Single Dose ◽  
Acute Toxicity ◽  
Centella Asiatica ◽  
Toxicity Study ◽  
Histopathological Analysis ◽  
Acute Administration ◽  
In Vivo Toxicity ◽  
Evolvulus Alsinoides ◽  
Ethanolic Extracts

AIM: We aimed to investigate several parameters after the in vivo acute and sub-acute administration of ethanolic extracts from E. alsinoides & C. asiatica. METHODS: Malignant Ovarian Germ Cell Tumors for in vivo toxicity study guidelines 423 and 407 of Organization for Economic Co-operation and Development (OECD) were followed for acute and sub-acute toxicity assays respectively. For LD50 evaluation, a single dose of ethanolic extracts of Evolvulus alsinoides L. (EEA) and ethanolic extracts of Centella asiatica (ECA) was orally administered to mice at doses of 200, 400, 800, 1600 and 2000 mg/kg. Then the animals were observed for 72 hours. For acute toxicity evaluation, a single dose of both extracts was orally administered to mice at doses of 300, 600, 1200 and 2000 mg/kg and the animals were observed for 14 days. In the sub-acute study, the extracts were orally administered to mice for 28 days at doses of 300, 600, 1200 and 2000 mg/kg. To assess the toxicological effects, animals were closely observed on general behaviour, clinical signs of toxicity, body weight, food and water intake. At the end of the study, it was performed biochemical and hematological evaluations, as well as histopathological analysis from the following organs: brain, heart, liver, and kidney. RESULTS: The oral administration of E. alsinoides and C. asiatica ethanolic extracts, i.e. EEA 300, EEA 600, EEA 1200, EEA 2000, ECA 300, ECA 600, ECA 1200 & ECA 2000 mg/kg doses showed no moral toxicity effect in LD50, acute and sub-acute toxicity parameters. CONCLUSION: In this study, we had found that E. alsinoides & C. asiatica extract at different doses cause no mortality in acute and sub-acute toxicity study. Also, histopathology of kidney, liver, heart, and brain showed no alterations in tissues morphology.

scholarly journals In vivo toxicity study of Lantana camara

2011 ◽  
Vol 1 (3) ◽  
pp. 230-232 ◽  
Author(s):  
Badakhshan Mahdi Pour ◽  
Sreenivasan Sasidharan
Keyword(s):  
Lantana Camara ◽  
Toxicity Study ◽  
In Vivo Toxicity

scholarly journals Felodipine loaded PLGA nanoparticles: preparation, physicochemical characterization and in vivo toxicity study

2014 ◽  
Vol 1 (1) ◽  
Author(s):  
Utpal Jana ◽  
Anjan Kumar Mohanty ◽  
Sovan Lal Pal ◽  
Prabal Kumar Manna ◽  
Guru Prasad Mohanta
Keyword(s):  
Physicochemical Characterization ◽  
Plga Nanoparticles ◽  
Toxicity Study ◽  
In Vivo Toxicity

In vivo toxicity study of N-1-sulfonylcytosine derivatives and their mechanisms of action in cervical carcinoma cell line

2011 ◽  
Vol 30 (3) ◽  
pp. 981-990 ◽  
Author(s):  
Jelena Kašnar-Šamprec ◽  
Ivana Ratkaj ◽  
Katarina Mišković ◽  
Marina Pavlak ◽  
Mirela Baus-Lončar ◽  
...  
Keyword(s):  
Cell Line ◽  
Cervical Carcinoma ◽  
Carcinoma Cell ◽  
Mechanisms Of Action ◽  
Carcinoma Cell Line ◽  
Toxicity Study ◽  
In Vivo Toxicity ◽  
Cervical Carcinoma Cell Line

In Vivo Toxicity Study of Rhodamine 6G in the Rat Retina

2008 ◽  
Vol 49 (5) ◽  
pp. 2120 ◽  
Author(s):  
Sebastian Thaler ◽  
Christos Haritoglou ◽  
Tomasz J. Choragiewicz ◽  
Andre Messias ◽  
Aneta Baryluk ◽  
...  
Keyword(s):  
Rhodamine 6G ◽  
Toxicity Study ◽  
Rat Retina ◽  
In Vivo Toxicity
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