Chiral ruthenium/diamine-functionalized mesoporous silica is synthesized and its application in the one-pot synthesis of chiral β-hydroxy sulfones is investigated.
This work reflects Ru-tethered-TsDPEN as an active chiral catalyst for one pot selective synthesis of optically active α-substituted alcohols and its derivatives from α-bromo ketones in the presence of dimethylamine borane (DMAB) as the hydrogen source.
Integrated catalytic dehydration/transfer-hydrogenation/alcoholysis in a one-pot cascade model to realize efficient conversion of xylose into alkyl levulinate is creditable in terms of sustainability and process economics.
A one-pot deracemization of β,γ-alkynyl α-amino esters consisting of an aerobic oxidation and chiral phosphoric acid-catalyzed asymmetric transfer hydrogenation has been described.
Highly Enantioselective One-Pot Synthesis of Chiral β-Heterosubstituted Alcohols via Ruthenium–Prolinamide-Catalyzed Asymmetric Transfer Hydrogenation