scholarly journals Simultaneous Binding of Folic Acid and Methotrexate to Human Serum Albumin: Insights into the Structural Changes of Protein and the Location and Competitive Displacement of Drugs

ACS Omega ◽  
2018 ◽  
Vol 3 (1) ◽  
pp. 246-253 ◽  
Author(s):  
Sudipta Panja ◽  
Deb Kumar Khatua ◽  
Mintu Halder
Keyword(s):  
Folic Acid ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Structural Changes ◽  
Competitive Displacement

Rapid detection and initial characterization of genetic variants of human serum albumin

1991 ◽  
Vol 37 (7) ◽  
pp. 1221-1224 ◽  
Author(s):  
J Merle Sheat ◽  
Robert J Peach ◽  
Peter M George
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Genetic Variants ◽  
Gel Electrophoresis ◽  
Structural Changes ◽  
Polyacrylamide Gel Electrophoresis ◽  
Sodium Dodecyl

Abstract We have studied the detection and classification of genetic variants of human serum albumin by electrophoresis. Samples from 10 patients who were heterozygous for eight different albumin variants were studied by two methods. In agarose gel electrophoresis, each of these variants has an abnormal mobility and can be classified on the basis that structural changes at the N-terminus abolish 63Ni binding. In sodium dodecyl sulfate-polyacrylamide gel electrophoresis of whole serum, glycosylated variants are easily detected because of their greater apparent molecular mass.

scholarly journals Folic acid receptor-targeted human serum albumin nanoparticle formulation of cabazitaxel for tumor therapy

2018 ◽  
Vol Volume 14 ◽  
pp. 135-148 ◽  
Author(s):  
Yating Sun ◽  
Yarong Zhao ◽  
Shanshan Teng ◽  
Fei Hao ◽  
Huan Zhang ◽  
...  
Keyword(s):  
Folic Acid ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Tumor Therapy ◽  
Acid Receptor ◽  
Nanoparticle Formulation ◽  
Folic Acid Receptor

Antioxidant capacity and structural changes of human serum albumin from patients in advanced stages of diabetic nephropathy and the effect of the dialysis

2015 ◽  
Vol 404 (1-2) ◽  
pp. 193-201 ◽  
Author(s):  
Marisol Rosas-Díaz ◽  
Menandro Camarillo-Cadena ◽  
Andrés Hernández-Arana ◽  
Eva Ramón-Gallegos ◽  
Rafael Medina-Navarro
Keyword(s):  
Diabetic Nephropathy ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Antioxidant Capacity ◽  
Human Serum ◽  
Structural Changes ◽  
Advanced Stages

Hyperglycemia induced reactive species trigger structural changes in human serum albumin of type 1 diabetic subjects

2018 ◽  
Vol 107 ◽  
pp. 2141-2149 ◽  
Author(s):  
Zarina Arif ◽  
Km Neelofar ◽  
Mir Yasir Arfat ◽  
Asif Zaman ◽  
Akhlas Tarannum ◽  
...  
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Structural Changes ◽  
Reactive Species
Sign in / Sign up

Export Citation Format

Share Document