scholarly journals Solid-State Versatility of the Molecular Salts/Cocrystals of 2-Chloro-4-nitrobenzoic Acid: A Case Study on Halogen Bonds

ACS Omega ◽  
2017 ◽  
Vol 2 (10) ◽  
pp. 7146-7162 ◽  
Author(s):  
Madhavi Oruganti ◽  
Sunil Kumar Nechipadappu ◽  
Pavan A. Khade ◽  
Darshak R. Trivedi
Keyword(s):  
Solid State ◽  
Halogen Bonds ◽  
Nitrobenzoic Acid ◽  
Molecular Salts

Dual approach for concomitant monitoring of dissolution and transformation at solid-state. Mebendazole salts case study

2020 ◽  
Vol 55 ◽  
pp. 101344 ◽  
Author(s):  
Gerardo E. Camí ◽  
Elena V. Brusau ◽  
Griselda E. Narda ◽  
Rubén M. Maggio
Keyword(s):  
Solid State ◽  
Dual Approach

scholarly journals Switching-On Fluorescence by Copper (II) and Basic Anions: A Case Study with a Pyrene-Functionalized Squaramide

Molecules ◽  
2021 ◽  
Vol 26 (5) ◽  
pp. 1301
Author(s):  
Giacomo Picci ◽  
Jessica Milia ◽  
Maria Carla Aragoni ◽  
Massimiliano Arca ◽  
Simon J. Coles ◽  
...  
Keyword(s):  
Solid State ◽  
Copper Complex ◽  
Receptor Complex ◽  
Emission Properties ◽  
Naked Eye ◽  
Intense Emission ◽  
Uv Lamp

The new symmetric acyclic N,N’-bis(1-pyrenyl) squaramide (H2L) functionalized with the pyrene moiety as a fluorogenic fragment has been designed and its ability to selectively detect specific anions and metals investigated. H2L selectively binds Cl− both in solution (DMSO 0.5% H2O and MeCN) and in the solid state, and allows to selectively detect Cu2+ in MeCN with the formation of a 2:1 metal-receptor complex, with a green intense emission appreciable by naked eye under the UV lamp. The H2L copper complex preserves its emission properties in the presence of Cl−. The addition of basic anions (OH−, CN−, and F−) up to 10 equivalents caused the deprotonation of the squaramide NHs and a dramatic change of the emission properties of the H2L copper complex.

scholarly journals Convenient Access to Functionalized Non-Symmetrical Atropisomeric 4,4′-Bipyridines

Compounds ◽  
2021 ◽  
Vol 1 (2) ◽  
pp. 58-74
Author(s):  
Emmanuel Aubert ◽  
Emmanuel Wenger ◽  
Paola Peluso ◽  
Victor Mamane
Keyword(s):  
Solid State ◽  
Intermolecular Interactions ◽  
Medicinal Chemistry ◽  
Crystal Packing ◽  
Cross Coupling ◽  
Coupling Reactions ◽  
Halogen Bonds ◽  
Cross Coupling Reactions ◽  
Cyano Groups ◽  
Post Functionalization

Non-symmetrical chiral 4,4′-bipyridines have recently found interest in organocatalysis and medicinal chemistry. In this regard, the development of efficient methods for their synthesis is highly desirable. Herein, a series of non-symmetrical atropisomeric polyhalogenated 4,4′-bipyridines were prepared and further functionalized by using cross-coupling reactions. The desymmetrization step is based on the N-oxidation of one of the two pyridine rings of the 4,4′-bipyridine skeleton. The main advantage of this methodology is the possible post-functionalization of the pyridine N-oxide, allowing selective introduction of chlorine, bromine or cyano groups in 2- and 2′-postions of the chiral atropisomeric 4,4′-bipyridines. The crystal packing in the solid state of some newly prepared derivatives was analyzed and revealed the importance of halogen bonds in intermolecular interactions.

Do Solid-State Structures Reflect Lewis Acidity Trends of Heavier Group 13 Trihalides? Experimental and Theoretical Case Study

2012 ◽  
Vol 51 (21) ◽  
pp. 11602-11611 ◽  
Author(s):  
Alexey Y. Timoshkin ◽  
Michael Bodensteiner ◽  
Tatiana N. Sevastianova ◽  
Anna S. Lisovenko ◽  
Elena I. Davydova ◽  
...  
Keyword(s):  
Solid State ◽  
Lewis Acidity ◽  
Group 13 ◽  
Solid State Structures

scholarly journals Surface Acidity and Solid-State Compatibility of Excipients with an Acid-Sensitive API: Case Study of Atorvastatin Calcium

2014 ◽  
Vol 16 (2) ◽  
pp. 354-363 ◽  
Author(s):  
Ramprakash Govindarajan ◽  
Margaret Landis ◽  
Bruno Hancock ◽  
Larry A. Gatlin ◽  
Raj Suryanarayanan ◽  
...  
Keyword(s):  
Solid State ◽  
Surface Acidity ◽  
Atorvastatin Calcium

scholarly journals Probing solid-state reaction through microstrain: A case study on synthesis of LiCoO2

2020 ◽  
Vol 469 ◽  
pp. 228422
Author(s):  
Jihyeon Gim ◽  
Yinzhi Zhang ◽  
Han Gao ◽  
Gui-Liang Xu ◽  
Fangmin Guo ◽  
...  
Keyword(s):  
Solid State ◽  
Solid State Reaction

Observation of strong halogen bonds in the solid state structures of bis-haloimidazolium macrocycles

CrystEngComm ◽  
2014 ◽  
Vol 16 (18) ◽  
pp. 3722-3729 ◽  
Author(s):  
Nicholas G. White ◽  
Antonio Caballero ◽  
Paul D. Beer
Keyword(s):  
Solid State ◽  
Halogen Bonds ◽  
Solid State Structures

Influence of Preparation Methods on Solid State Supersaturation of Amorphous Solid Dispersions: A Case Study with Itraconazole and Eudragit E100

2010 ◽  
Vol 27 (5) ◽  
pp. 775-785 ◽  
Author(s):  
Sandrien Janssens ◽  
Ann De Zeure ◽  
Amrit Paudel ◽  
Jan Van Humbeeck ◽  
Patrick Rombaut ◽  
...  
Keyword(s):  
Solid State ◽  
Solid Dispersions ◽  
Amorphous Solid ◽  
Amorphous Solid Dispersions ◽  
Preparation Methods ◽  
Eudragit E100
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