scholarly journals Endosomal Size and Membrane Leakiness Influence Proton Sponge-Based Rupture of Endosomal Vesicles

ACS Nano ◽  
2018 ◽  
Vol 12 (3) ◽  
pp. 2332-2345 ◽  
Author(s):  
Lotte M. P. Vermeulen ◽  
Toon Brans ◽  
Sangram K. Samal ◽  
Peter Dubruel ◽  
Jo Demeester ◽  
...  
Keyword(s):  
Proton Sponge ◽  
Endosomal Vesicles

scholarly journals Efficient Protein Transduction Method Using Cationic Peptides and Lipids

2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Kei Yamaguchi ◽  
Mari Inoue ◽  
Naoki Goshima
Keyword(s):  
Protein Delivery ◽  
Cationic Lipid ◽  
Living Cells ◽  
Protein Transduction ◽  
Cationic Peptides ◽  
Proton Sponge ◽  
Protein Transduction Domains ◽  
Cargo Proteins ◽  
Endosomal Vesicles ◽  
Novel Protein

Cationic peptides termed protein transduction domains (PTDs) have been shown to cross biological membranes efficiently. However, proteins transduced by PTDs become entrapped within the endosomal vesicles and are not delivered into organelles. We have developed a novel protein delivery system to enhance the proton sponge effect, which results in rupture of the endosomes, by using a mixture of Wr-T transporter peptide and a commercially available cationic lipid reagent. This peptide and cationic lipid reagent mixture efficiently delivers a variety of cargo proteins into living cells by releasing them from the endosomes.

Proton sponge promotion of electrochemical CO2 reduction to multi-carbon products

Joule ◽  
2021 ◽  
Author(s):  
Lei Fan ◽  
Chun-Yen Liu ◽  
Peng Zhu ◽  
Chuan Xia ◽  
Xiao Zhang ◽  
...  
Keyword(s):  
Co2 Reduction ◽  
Proton Sponge ◽  
Electrochemical Co2 Reduction

scholarly journals Synthesis and Crystal Structure of a Small Bicyclic Tetraaza Proton Sponge, 1,4,7,10-Tetraazabicyclo[5.5.3]pentadecane Dibromide Perchlorate.

1995 ◽  
Vol 49 ◽  
pp. 547-554 ◽  
Author(s):  
Johan Springborg ◽  
Pauli Kofod ◽  
Carl Erik Olsen ◽  
Hans Toftlund ◽  
Inger Søtofte ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Proton Sponge ◽  
Synthesis And Crystal Structure

ChemInform Abstract: 1,8-Bis(diphenylphosphino)naphthalene: A Rigid Chelating Diphosphine Analogue of Proton Sponge.

ChemInform ◽  
2010 ◽  
Vol 25 (7) ◽  
pp. no-no
Author(s):  
R. D. JACKSON ◽  
S. JAMES ◽  
A. G. ORPEN ◽  
P. G. PRINGLE
Keyword(s):  
Proton Sponge

Ionization Behavior of Chitosan and Chitosan–DNA Polyplexes Indicate That Chitosan Has a Similar Capability to Induce a Proton-Sponge Effect as PEI

2013 ◽  
Vol 14 (6) ◽  
pp. 1732-1740 ◽  
Author(s):  
Isabelle Richard ◽  
Marc Thibault ◽  
Gregory De Crescenzo ◽  
Michael D. Buschmann ◽  
Marc Lavertu
Keyword(s):  
Proton Sponge ◽  
Ionization Behavior

Unusual Reactivity of “Proton Sponge” as a Hydride Donor to Transition Metals:  Synthesis and Structural Characterization of Fluoroalkyl(hydrido) Complexes of Iridium(III) and Rhodium(III)

2001 ◽  
Vol 20 (14) ◽  
pp. 3190-3197 ◽  
Author(s):  
Russell P. Hughes ◽  
Ivan Kovacik ◽  
Danielle C. Lindner ◽  
Jeremy M. Smith ◽  
Stefan Willemsen ◽  
...  
Keyword(s):  
Transition Metals ◽  
Structural Characterization ◽  
Proton Sponge
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