scholarly journals An Enzyme-Free Signal Amplification Technique for Ultrasensitive Colorimetric Assay of Disease Biomarkers

ACS Nano ◽  
2017 ◽  
Vol 11 (2) ◽  
pp. 2052-2059 ◽  
Author(s):  
Haihang Ye ◽  
Kuikun Yang ◽  
Jing Tao ◽  
Yijing Liu ◽  
Qian Zhang ◽  
...  
Keyword(s):  
Signal Amplification ◽  
Colorimetric Assay ◽  
Disease Biomarkers ◽  
Amplification Technique

Sensitive detection of microRNA using QCM biosensors: sandwich hybridization and signal amplification by TiO2 nanoparticles

2020 ◽  
Vol 12 (42) ◽  
pp. 5103-5109
Author(s):  
Ji Yoon Lim ◽  
Soo Suk Lee
Keyword(s):  
Tio2 Nanoparticles ◽  
Signal Amplification ◽  
Sensitive Detection ◽  
Sandwich Hybridization ◽  
Amplification Technique

A QCM biosensor for the detection of miR-21 has been demonstrated along with sandwich hybridization and TiO2 nanoparticle-based photocatalytic signal amplification technique.

An aptamer-based colorimetric assay for chloramphenicol using a polymeric HRP-antibody conjugate for signal amplification

2015 ◽  
Vol 182 (15-16) ◽  
pp. 2551-2559 ◽  
Author(s):  
Huiju Gao ◽  
Daodong Pan ◽  
Ning Gan ◽  
Jinxuan Cao ◽  
Yangying Sun ◽  
...  
Keyword(s):  
Signal Amplification ◽  
Colorimetric Assay ◽  
Antibody Conjugate

Ultrasensitive detection of disease biomarkers using an immuno-wall device with enzymatic amplification

The Analyst ◽  
2019 ◽  
Vol 144 (15) ◽  
pp. 4589-4595 ◽  
Author(s):  
Keine Nishiyama ◽  
Toshihiro Kasama ◽  
Seiya Nakamata ◽  
Koya Ishikawa ◽  
Daisuke Onoshima ◽  
...  
Keyword(s):  
Signal Amplification ◽  
Sandwich Immunoassay ◽  
Ultrasensitive Detection ◽  
Disease Biomarkers ◽  
Enzymatic Amplification

We present a fluorometric sandwich immunoassay for biomarkers utilizing an antibody-modified microfabricated wall and antibody labeled with an enzyme for signal amplification.

A Feasible Self-assembly Near-Infrared Fluorescence Sensor for Acid Phosphatase Detection and Cell Imaging

The Analyst ◽  
2021 ◽  
Author(s):  
Shuangqin Li ◽  
Yaya Wang ◽  
Shuai Mu ◽  
Jinlong Zhang ◽  
Xiaoyan Liu ◽  
...  
Keyword(s):  
Acid Phosphatase ◽  
Self Assembly ◽  
Signal Amplification ◽  
Near Infrared ◽  
Cell Imaging ◽  
Near Infrared Fluorescence ◽  
Disease Biomarkers ◽  
Amplification Strategy ◽  
Multi Mode ◽  
Limited Accuracy

Abstract Single signal amplification strategy is significant for detecting of various disease biomarkers, however, which is restricted by the limited accuracy. The multi-signal and multi-mode methods have efficiently overcome this...

Detection of thrombin based on aptamer isothermal exponential signal amplification technique

The Analyst ◽  
2015 ◽  
Vol 140 (19) ◽  
pp. 6489-6492 ◽  
Author(s):  
Xiaotong Shen ◽  
Menghua Zhang ◽  
Shuyan Niu ◽  
Chao Shi
Keyword(s):  
Signal Amplification ◽  
Protein Detection ◽  
Amplification Technique

In this report, a strategy based on an aptameric molecule switch to realize homogeneous and isothermal signal exponential amplification and protein detection has been described.

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