scholarly journals Modulatory Role of Surface Coating of Superparamagnetic Iron Oxide Nanoworms in Complement Opsonization and Leukocyte Uptake

ACS Nano ◽  
2015 ◽  
Vol 9 (11) ◽  
pp. 10758-10768 ◽  
Author(s):  
Swetha Inturi ◽  
Guankui Wang ◽  
Fangfang Chen ◽  
Nirmal K. Banda ◽  
V. Michael Holers ◽  
...  
2020 ◽  
Vol 10 (2) ◽  
pp. 166-174
Author(s):  
Mehdi Khoshneviszadeh ◽  
Sarah Zargarnezhad ◽  
Younes Ghasemi ◽  
Ahmad Gholami

Background: Magnetic cell immobilization has been introduced as a novel, facile and highly efficient approach for cell separation. A stable attachment between bacterial cell wall with superparamagnetic iron oxide nanoparticles (SPIONs) would enable the microorganisms to be affected by an outer magnetic field. At high concentrations, SPIONs produce reactive oxygen species in cytoplasm, which induce apoptosis or necrosis in microorganisms. Choosing a proper surface coating could cover the defects and increase the efficiency. Methods: In this study, asparagine, APTES, lipo-amino acid and PEG surface modified SPIONs was synthesized by co-precipitation method and characterized by FTIR, TEM, VSM, XRD, DLS techniques. Then, their protective effects against four Gram-positive and Gram-negative bacterial strains including Enterococcus faecalis, Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa were examined through microdilution broth and compared to naked SPION. Results: The evaluation of characterization results showed that functionalization of magnetic nanoparticles could change their MS value, size and surface charges. Also, the microbial analysis revealed that lipo-amino acid coated magnetic nanoparticles has the least adverse effect on microbial strain among tested SPIONs. Conclusion: This study showed lipo-amino acid could be considered as the most protective and even promotive surface coating, which is explained by its optimizing effect on cell penetration and negligible reductive effects on magnetic properties of SPIONs. lipo-amino acid coated magnetic nanoparticles could be used in microbial biotechnology and industrial microbiology.


2003 ◽  
Vol 18 (6) ◽  
pp. 1309-1313 ◽  
Author(s):  
Arvind Sinha ◽  
Suprabha Nayar ◽  
G. V. S. Murthy ◽  
P. A. Joy ◽  
V. Rao ◽  
...  

Matrix-mediated in situ synthesis of monodispersed magnetite and maghemite nanoparticles (2–16 nm) was carried out using the cavities present in gels of globular proteins such as egg white and bovine serum albumin. Under stringent conditions, spatial-charge-distribution-assisted molecular recognition of proteins for inorganic ions led to the site- and polymorph-specific synthesis of superparamagnetic iron oxide particles. A transformation from magnetite to maghemite as a nucleating phase could be observed by partially denaturing the egg white protein, signifying the delicate role of quaternary structure of proteins under different reaction conditions, in determining the size and shape of the polymorph.


2019 ◽  
Vol 21 (30) ◽  
pp. 16413-16417 ◽  
Author(s):  
Meera Sathyan ◽  
M. K. Jayaraj ◽  
Honey John

The role of magnetite nanoparticles in the scrolling and unscrolling of graphene sheets.


Sign in / Sign up

Export Citation Format

Share Document