Capturing Magnesium Ions via Microfluidic Hydrogel Microspheres for Promoting Cancellous Bone Regeneration

ACS Nano ◽  
2021 ◽  
Author(s):  
Zhenyu Zhao ◽  
Gen Li ◽  
Huitong Ruan ◽  
Keyi Chen ◽  
Zhengwei Cai ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Cancellous Bone ◽  
Magnesium Ions ◽  
Hydrogel Microspheres

Stem cell-laden injectable hydrogel microspheres for cancellous bone regeneration

2020 ◽  
Vol 393 ◽  
pp. 124715 ◽  
Author(s):  
Jiezhou Wu ◽  
Gen Li ◽  
Tingjun Ye ◽  
Guanghua Lu ◽  
Runmin Li ◽  
...  
Keyword(s):  
Stem Cell ◽  
Bone Regeneration ◽  
Cancellous Bone ◽  
Injectable Hydrogel ◽  
Hydrogel Microspheres

A cancellous bone matrix system with specific mineralisation degrees for mesenchymal stem cell differentiation and bone regeneration

2019 ◽  
Vol 7 (6) ◽  
pp. 2452-2467 ◽  
Author(s):  
Shijie Liu ◽  
Yiyun Wang ◽  
Jian Wang ◽  
Pengcheng Qiu ◽  
Shengyu Wang ◽  
...  
Keyword(s):  
Stem Cell ◽  
Cell Differentiation ◽  
Mesenchymal Stem Cell ◽  
Bone Regeneration ◽  
Cancellous Bone ◽  
Bone Matrix ◽  
Stem Cell Differentiation ◽  
Matrix System ◽  
Mesenchymal Stem Cell Differentiation ◽  
Regenerative Therapies

Bone regenerative therapies have been explored using various biomaterial systems.

The role of magnesium ions in bone regeneration involves the canonical Wnt signaling pathway

2019 ◽  
Vol 98 ◽  
pp. 246-255 ◽  
Author(s):  
Chu-Chih Hung ◽  
Amy Chaya ◽  
Kai Liu ◽  
Konstantinos Verdelis ◽  
Charles Sfeir
Keyword(s):  
Wnt Signaling ◽  
Bone Regeneration ◽  
Signaling Pathway ◽  
Wnt Signaling Pathway ◽  
Magnesium Ions ◽  
Canonical Wnt Signaling ◽  
Canonical Wnt

Ceramics based on calcium phosphates substituted with magnesium ions for bone regeneration

2019 ◽  
Vol 17 (1) ◽  
pp. 342-353 ◽  
Author(s):  
Cristina‐Daniela Ghițulică ◽  
Andreia Cucuruz ◽  
Georgeta Voicu ◽  
Andrei T. Cucuruz ◽  
Sorina Dinescu ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Calcium Phosphates ◽  
Magnesium Ions

Preparation of polylactide scaffolds for cancellous bone regeneration – preliminary investigation and optimization of the process

2019 ◽  
Vol 91 (9) ◽  
pp. 1509-1519 ◽  
Author(s):  
Monika Budnicka ◽  
Joanna Trzaskowska ◽  
Agnieszka Gadomska-Gajadhur ◽  
Paweł Ruśkowski ◽  
Ludwik Synoradzki
Keyword(s):  
Bone Regeneration ◽  
Cancellous Bone ◽  
Open Porosity ◽  
Phase Inversion ◽  
Preliminary Investigation ◽  
Volume Ratio ◽  
Inversion Method ◽  
Regression Equations ◽  
Pouring Temperature ◽  
Phase Inversion Method

Abstract Polylactide scaffolds were prepared for the cancellous bone regeneration by the phase inversion method with freeze-extraction variant. A preliminary investigation and the optimization of the process were performed. For the obtained scaffolds, regression equations determining the effect: PLLA concentration by weight in 1,4-dioxane; volume ratio of the porophore/PLLA solution in 1,4-dioxane; and implant-forming solution pouring temperature, on the open porosity and mass absorbability were determined. The conditions in which the obtained implants were characterized by the maximal absorbability with the open porosity greater than 90 % were obtained.

Adipose-Derived Stem Cells Combined with a Demineralized Cancellous Bone Substrate for Bone Regeneration

2012 ◽  
Vol 18 (13-14) ◽  
pp. 1313-1321 ◽  
Author(s):  
Yaling Shi ◽  
Jerry R. Niedzinski ◽  
Adrian Samaniego ◽  
Simon Bogdansky ◽  
Brent L. Atkinson
Keyword(s):  
Stem Cells ◽  
Bone Regeneration ◽  
Cancellous Bone ◽  
Adipose Derived Stem Cells

scholarly journals Resorbable Mg2+-Containing Phosphates for Bone Tissue Repair

2021 ◽  
Author(s):  
Gilyana Kazakova ◽  
Tatiana Safronova ◽  
Daniil Golubchikov ◽  
Olga Shevtsova ◽  
Julietta Rau
Keyword(s):  
Bone Regeneration ◽  
Bone Tissue ◽  
Tissue Repair ◽  
Early Stage ◽  
Biological Properties ◽  
Magnesium Ions ◽  
Comprehensive Overview ◽  
Phosphate Ions ◽  
Great Relevance

Materials based on Mg2+-containing phosphates are gaining great relevance in the field of bone tissue repair via regenerative medicine methods. Magnesium ions, together with condensed phosphate ions, play a significant role in the process of bone remodeling, affecting the early stage of bone regeneration through active participation in the process of osteosynthesis. Here we pro-vide a comprehensive overview of the usage of biomaterials based on magnesium phosphate and magnesium calcium phosphate in bone reconstruction. The role of magnesium ions in angiogene-sis, an important process associated with osteogenesis, is considered. Finally, the biological properties of magnesium phosphates for bone regeneration are summarized. They show promis-ing results in terms of use as bone replacement material.

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