Electrophoretic Transport of Single-Stranded DNA through a Two Dimensional Nanopore Patterned on an In-Plane Heterostructure

ACS Nano ◽  
2020 ◽  
Vol 14 (10) ◽  
pp. 13137-13145
Author(s):  
Binquan Luan ◽  
Marcelo A. Kuroda
Keyword(s):  
Two Dimensional ◽  
Single Stranded Dna ◽  
Electrophoretic Transport

scholarly journals Spontaneous ssDNA stretching on graphene and hexagonal boron nitride in plane heterostructures

2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Binquan Luan ◽  
Ruhong Zhou
Keyword(s):  
Boron Nitride ◽  
Genome Analysis ◽  
Hexagonal Boron Nitride ◽  
Persistence Length ◽  
Atomic Resolution ◽  
Two Dimensional ◽  
Planar Surface ◽  
Single Stranded Dna ◽  
Double Stranded Dna ◽  
Material Fabrication

Abstract Single-stranded DNA (ssDNA) molecules in solution typically form coiled structures, therefore stretching ssDNA is extremely crucial before applying any nanotechnology for ssDNA analysis. Recent advances in material fabrication enable the deployment of nanochannels to manipulate, stretch, sort and map double-stranded DNA (dsDNA) molecules, however nanochannels fail to stretch ssDNA molecules due to the ultra-short persistence length and the potential nonspecific-interaction-induced clogging. Given the significance of ssDNA stretching in genome analysis, here we report an ssDNA stretching platform: two dimensional in-plane heterostructure comprising graphene and hexagonal boron nitride (h-BN), and show that ssDNA can be stretched on a h-BN nanostripe sandwiched between two adjacent graphene domains (“nanochannel”). We further show that with a biasing voltage the stretched ssDNA can be electrophoretically transported along the “nanochannel”, allowing easy controls/manipulations. When being conveniently integrated with existing atomic resolution sensors, the heterostructure platform paves the way for sequencing DNA on a planar surface.

scholarly journals Self-assembly of Complex Two-dimensional Shapes from Single-stranded DNA Tiles

10.3791/52486 ◽  
2015 ◽  
Author(s):  
Bryan Wei ◽  
Michelle K. Vhudzijena ◽  
Joanna Robaszewski ◽  
Peng Yin
Keyword(s):  
Self Assembly ◽  
Two Dimensional ◽  
Single Stranded Dna ◽  
Dna Tiles

Two-dimensional strandness-dependent electrophoresis: A method to characterize single-stranded DNA, double-stranded DNA, and RNA–DNA hybrids in complex samples

2006 ◽  
Vol 350 (1) ◽  
pp. 120-127 ◽  
Author(s):  
Gudmundur H. Gunnarsson ◽  
Bjarki Gudmundsson ◽  
Hans G. Thormar ◽  
Arni Alfredsson ◽  
Jon J. Jonsson
Keyword(s):  
Two Dimensional ◽  
Single Stranded Dna ◽  
Complex Samples ◽  
Dna And Rna ◽  
Double Stranded Dna

Spectrophotometric measurements of objective-prism spectra

1966 ◽  
Vol 24 ◽  
pp. 118-119
Author(s):  
Th. Schmidt-Kaler
Keyword(s):  
Progress Report ◽  
Two Dimensional ◽  
Objective Prism ◽  
Made In

I should like to give you a very condensed progress report on some spectrophotometric measurements of objective-prism spectra made in collaboration with H. Leicher at Bonn. The procedure used is almost completely automatic. The measurements are made with the help of a semi-automatic fully digitized registering microphotometer constructed by Hög-Hamburg. The reductions are carried out with the aid of a number of interconnected programmes written for the computer IBM 7090, beginning with the output of the photometer in the form of punched cards and ending with the printing-out of the final two-dimensional classifications.

Introductory paper

1966 ◽  
Vol 24 ◽  
pp. 3-5
Author(s):  
W. W. Morgan
Keyword(s):  
Line Intensity ◽  
Classification Scheme ◽  
Two Dimensional ◽  
Spectral Classification ◽  
Dimensional Array ◽  
Rr Lyrae ◽  
Metallic Line ◽  
Introductory Paper ◽  
Parameter Varying ◽  
Definition Of

1. The definition of “normal” stars in spectral classification changes with time; at the time of the publication of theYerkes Spectral Atlasthe term “normal” was applied to stars whose spectra could be fitted smoothly into a two-dimensional array. Thus, at that time, weak-lined spectra (RR Lyrae and HD 140283) would have been considered peculiar. At the present time we would tend to classify such spectra as “normal”—in a more complicated classification scheme which would have a parameter varying with metallic-line intensity within a specific spectral subdivision.

A one-dimensional self-gravitating stellar gas

1966 ◽  
Vol 25 ◽  
pp. 46-48 ◽  
Author(s):  
M. Lecar
Keyword(s):  
Gravitational Field ◽  
Phase Space ◽  
Motion Picture ◽  
Space Distribution ◽  
Two Dimensional ◽  
One Dimensional ◽  
Phase Space Distribution ◽  
Dimensional Phase Space ◽  
The Mean

“Dynamical mixing”, i.e. relaxation of a stellar phase space distribution through interaction with the mean gravitational field, is numerically investigated for a one-dimensional self-gravitating stellar gas. Qualitative results are presented in the form of a motion picture of the flow of phase points (representing homogeneous slabs of stars) in two-dimensional phase space.

Analysis of the 9th November 1990 flare

2000 ◽  
Vol 179 ◽  
pp. 229-232
Author(s):  
Anita Joshi ◽  
Wahab Uddin
Keyword(s):  
Image Processing ◽  
Two Dimensional ◽  
Temporal Behaviour ◽  
Contour Maps ◽  
Dimensional Measurements ◽  
Processing Software ◽  
Image Processing Software

AbstractIn this paper we present complete two-dimensional measurements of the observed brightness of the 9th November 1990Hαflare, using a PDS microdensitometer scanner and image processing software MIDAS. The resulting isophotal contour maps, were used to describe morphological-cum-temporal behaviour of the flare and also the kernels of the flare. Correlation of theHαflare with SXR and MW radiations were also studied.

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