Identification via a Parallel Hit Progression Strategy of Improved Small Molecule Inhibitors of the Malaria Purine Uptake Transporter that Inhibit Plasmodium falciparum Parasite Proliferation

Yvett Sosa; Roman Deniskin; I. J. Frame; Matthew S. Steiginga; Deepak Bandyopadhyay; Todd L. Graybill; Lorena A. Kallal; Michael T. Ouellette; Andrew J. Pope; Katherine L. Widdowson; Robert J. Young; Myles H. Akabas

doi:10.1021/acsinfecdis.9b00168

Identification via a Parallel Hit Progression Strategy of Improved Small Molecule Inhibitors of the Malaria Purine Uptake Transporter that Inhibit Plasmodium falciparum Parasite Proliferation

ACS Infectious Diseases ◽

10.1021/acsinfecdis.9b00168 ◽

2019 ◽

Vol 5 (10) ◽

pp. 1738-1753 ◽

Cited By ~ 2

Author(s):

Yvett Sosa ◽

Roman Deniskin ◽

I. J. Frame ◽

Matthew S. Steiginga ◽

Deepak Bandyopadhyay ◽

...

Keyword(s):

Plasmodium Falciparum ◽

Small Molecule ◽

Small Molecule Inhibitors ◽

Plasmodium Falciparum Parasite ◽

Falciparum Parasite

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Detection of Plasmodium Falciparum Parasite Intraerythrocytic Stages using One Dimensional Distributed Bragg Reflector Biosensor

10.1109/r10-htc53172.2021.9641586 ◽

2021 ◽

Author(s):

Ranjith B Gowda ◽

Manpreet Singh Manna ◽

Saara K ◽

Preeta Sharan

Keyword(s):

Plasmodium Falciparum ◽

Bragg Reflector ◽

Distributed Bragg Reflector ◽

One Dimensional ◽

Plasmodium Falciparum Parasite ◽

Falciparum Parasite

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Global distribution of polymorphisms associated with delayed Plasmodium falciparum parasite clearance following artemisinin treatment: Genotyping of archive blood samples

Parasitology International ◽

10.1016/j.parint.2014.11.002 ◽

2015 ◽

Vol 64 (3) ◽

pp. 267-273 ◽

Cited By ~ 5

Author(s):

Kenji Murai ◽

Richard Culleton ◽

Teruhiko Hisaoka ◽

Hiroyoshi Endo ◽

Toshihiro Mita

Keyword(s):

Plasmodium Falciparum ◽

Parasite Clearance ◽

Global Distribution ◽

Blood Samples ◽

Plasmodium Falciparum Parasite ◽

Falciparum Parasite

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Plasmodium Falciparum Parasite Development in Humanized Mice: Liver And Blood Stages

Humanized Mice for HIV Research ◽

10.1007/978-1-4939-1655-9_41 ◽

2014 ◽

pp. 519-528

Author(s):

Till Strowig ◽

Alexander Ploss

Keyword(s):

Plasmodium Falciparum ◽

Humanized Mice ◽

Parasite Development ◽

Plasmodium Falciparum Parasite ◽

Mice Liver ◽

Falciparum Parasite

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Association of high Plasmodium falciparum parasite densities with polyclonal microscopic infections in asymptomatic children from Toubacouta, Senegal

Malaria Journal ◽

10.1186/s12936-019-2684-3 ◽

2019 ◽

Vol 18 (1) ◽

Cited By ~ 1

Author(s):

Babacar Diouf ◽

Fode Diop ◽

Yakhya Dieye ◽

Cheikh Loucoubar ◽

Ibrahima Dia ◽

...

Keyword(s):

Plasmodium Falciparum ◽

Asymptomatic Children ◽

Plasmodium Falciparum Parasite ◽

Falciparum Parasite

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Antimalarial drug resistance: linking Plasmodium falciparum parasite biology to the clinic

Nature Medicine ◽

10.1038/nm.4381 ◽

2017 ◽

Vol 23 (8) ◽

pp. 917-928 ◽

Cited By ~ 181

Author(s):

Benjamin Blasco ◽

Didier Leroy ◽

David A Fidock

Keyword(s):

Drug Resistance ◽

Plasmodium Falciparum ◽

Antimalarial Drug ◽

Antimalarial Drug Resistance ◽

Plasmodium Falciparum Parasite ◽

Parasite Biology ◽

Falciparum Parasite

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Malaria case clinical profiles and Plasmodium falciparum parasite genetic diversity: a cross sectional survey at two sites of different malaria transmission intensities in Rwanda

Malaria Journal ◽

10.1186/s12936-016-1287-5 ◽

2016 ◽

Vol 15 (1) ◽

Cited By ~ 13

Author(s):

Fredrick Kateera ◽

Sam L. Nsobya ◽

Stephen Tukwasibwe ◽

Petra F. Mens ◽

Emmanuel Hakizimana ◽

...

Keyword(s):

Genetic Diversity ◽

Plasmodium Falciparum ◽

Malaria Transmission ◽

Malaria Case ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Plasmodium Falciparum Parasite ◽

Clinical Profiles ◽

Falciparum Parasite

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Seasonal variations in Plasmodium falciparum parasite prevalence assessed by varying diagnostic tests in asymptomatic children in southern Ghana

PLoS ONE ◽

10.1371/journal.pone.0199172 ◽

2018 ◽

Vol 13 (6) ◽

pp. e0199172 ◽

Cited By ~ 14

Author(s):

Ruth Ayanful-Torgby ◽

Neils B. Quashie ◽

Johnson N. Boampong ◽

Kim C. Williamson ◽

Linda E. Amoah

Keyword(s):

Plasmodium Falciparum ◽

Seasonal Variations ◽

Diagnostic Tests ◽

Parasite Prevalence ◽

Asymptomatic Children ◽

Plasmodium Falciparum Parasite ◽

Falciparum Parasite ◽

Southern Ghana

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Anti-folate drug resistance in Africa: meta-analysis of reported dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) mutant genotype frequencies in African Plasmodium falciparum parasite populations

Malaria Journal ◽

10.1186/1475-2875-9-247 ◽

2010 ◽

Vol 9 (1) ◽

pp. 247 ◽

Cited By ~ 63

Author(s):

Sankar Sridaran ◽

Shannon K McClintock ◽

Luke M Syphard ◽

Karen M Herman ◽

John W Barnwell ◽

...

Keyword(s):

Drug Resistance ◽

Plasmodium Falciparum ◽

Dihydrofolate Reductase ◽

Meta Analysis ◽

Mutant Genotype ◽

Dihydropteroate Synthase ◽

Genotype Frequencies ◽

Plasmodium Falciparum Parasite ◽

Parasite Populations ◽

Falciparum Parasite

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WITHDRAWN: Different antibody- and cytokine-mediated responses to Plasmodium falciparum parasite in two sympatric ethnic tribes living in Mali

Microbes and Infection ◽

10.1016/j.micinf.2005.03.005 ◽

2005 ◽

Author(s):

Salah E. Farouk ◽

Amagana Dolo ◽

Sàndor Bereczky ◽

Bourema Kouriba ◽

Boubacar Maiga ◽

...

Keyword(s):

Plasmodium Falciparum ◽

Plasmodium Falciparum Parasite ◽

Falciparum Parasite

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Molecular surveillance reveals the presence of pfhrp2 and pfhrp3 gene deletions in Plasmodium falciparum parasite populations in Uganda, 2017–2019

Malaria Journal ◽

10.1186/s12936-020-03362-x ◽

2020 ◽

Vol 19 (1) ◽

Cited By ~ 2

Author(s):

Agaba B. Bosco ◽

Karen Anderson ◽

Karryn Gresty ◽

Christiane Prosser ◽

David Smith ◽

...

Keyword(s):

Plasmodium Falciparum ◽

Molecular Surveillance ◽

Gene Deletions ◽

Plasmodium Falciparum Parasite ◽

Parasite Populations ◽

Falciparum Parasite

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