scholarly journals Optimization of Metabolic Oligosaccharide Engineering with Ac4GalNAlk and Ac4GlcNAlk by an Engineered Pyrophosphorylase

2021 ◽  
Author(s):  
Anna Cioce ◽  
Ganka Bineva-Todd ◽  
Anthony J. Agbay ◽  
Junwon Choi ◽  
Thomas M. Wood ◽  
...  
Keyword(s):  
Metabolic Oligosaccharide Engineering

AB107. P081. Metabolic oligosaccharide engineering of pancreatic cells: measurement of sialylation and identification of sialylated glycoproteins

2018 ◽  
Vol 1 (1) ◽  
pp. AB107-AB107
Author(s):  
Vrinda Dharmarha ◽  
Christopher Saeui ◽  
Jian Song ◽  
Hui Li ◽  
Howard Katz ◽  
...  
Keyword(s):  
Pancreatic Cells ◽  
Sialylated Glycoproteins ◽  
Metabolic Oligosaccharide Engineering

scholarly journals Metabolic oligosaccharide engineering with N-Acyl functionalized ManNAc analogs: Cytotoxicity, metabolic flux, and glycan-display considerations

2011 ◽  
Vol 109 (4) ◽  
pp. 992-1006 ◽  
Author(s):  
Ruben T. Almaraz ◽  
Udayanath Aich ◽  
Hargun S. Khanna ◽  
Elaine Tan ◽  
Rahul Bhattacharya ◽  
...  
Keyword(s):  
Metabolic Flux ◽  
Metabolic Oligosaccharide Engineering

scholarly journals A Sweet Galactose Transfer – Metabolic Oligosaccharide Engineering as a Tool to Study Glycans in Plasmodium Infection

2019 ◽  
Author(s):  
Annabel Kitowski ◽  
Gonçalo Bernardes
Keyword(s):  
Plasmodium Infection ◽  
Liver Stage ◽  
Hepatic Cells ◽  
Metabolic Oligosaccharide Engineering

The use of artificial galactose derivatives and labelling through iEDDA reaction in the liver stage of <i>Plasmodium </i>infection showed increased uptake in infected hepatic cells, through participation of GLUT1 transporters. Furthermore, unprotected derivatives are transferred from the mosquito host to the <i>Plasmodium</i> <i>berghei</i> parasite. This strategy has the potential to provide new insights into <i>Plasmodium</i> glycobiology.

Dual-Monitoring Glycosylation and Local pH in Live Cells by Metabolic Oligosaccharide Engineering with a Ratiometric Fluorescent Tag

2019 ◽  
Vol 91 (21) ◽  
pp. 13720-13728 ◽  
Author(s):  
Yan Wang ◽  
Nan Zhang ◽  
Shanshan Lu ◽  
Junyan Wang ◽  
Tao Bing ◽  
...  
Keyword(s):  
Live Cells ◽  
Fluorescent Tag ◽  
Local Ph ◽  
Metabolic Oligosaccharide Engineering

Rapid probing of sialylated glycoproteins in vitro and in vivo via metabolic oligosaccharide engineering of a minimal cyclopropene reporter

2015 ◽  
Vol 13 (13) ◽  
pp. 3911-3917 ◽  
Author(s):  
De-Cai Xiong ◽  
Jingjing Zhu ◽  
Ming-Jie Han ◽  
Hui-Xin Luo ◽  
Cong Wang ◽  
...  
Keyword(s):  
Sialylated Glycoproteins ◽  
Metabolic Oligosaccharide Engineering

A minimal and efficient cyclopropene chemical handle was identified both in vitro and in vivo.

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