One-Step Synthesis of Tunable Zinc-Based Nanohybrids as an Ultrasensitive DNA Signal Amplification Platform

2019 ◽  
Vol 12 (2) ◽  
pp. 2983-2990
Author(s):  
Wei Ma ◽  
Haishun Du ◽  
Miaomiao Zhang ◽  
Joakin Mori ◽  
Xuehong Ren ◽  
...  
Keyword(s):  
Signal Amplification ◽  
One Step

A colorimetric and ultrasensitive immunosensor for one-step pathogen detection via the combination of nanoparticle-triggered signal amplification and magnetic separation

RSC Advances ◽  
2015 ◽  
Vol 5 (122) ◽  
pp. 100633-100637 ◽  
Author(s):  
Yiping Chen ◽  
Mengxia Xie
Keyword(s):  
Magnetic Separation ◽  
Signal Amplification ◽  
Pathogen Detection ◽  
One Step

Colorimetric and ultrasensitive immunosensor for one-step pathogen detection via the combination of nanoparticle-triggered signal amplification and magnetic separation.

scholarly journals RNA pathogen detection with one-step reverse transcription PCR and strand-displacement based signal amplification

The Analyst ◽  
2013 ◽  
Vol 138 (5) ◽  
pp. 1544 ◽  
Author(s):  
Feng Du ◽  
Frank Streckenbach ◽  
Haodong Chen ◽  
Xin Huang ◽  
Zhuo Tang ◽  
...  
Keyword(s):  
Reverse Transcription ◽  
Signal Amplification ◽  
Pathogen Detection ◽  
Strand Displacement ◽  
Reverse Transcription Pcr ◽  
One Step ◽  
Displacement Based

Novel One-Tube-One-Step Real-Time Methodology for Rapid Transcriptomic Biomarker Detection: Signal Amplification by Ternary Initiation Complexes

2016 ◽  
Vol 88 (14) ◽  
pp. 7137-7144 ◽  
Author(s):  
Hiroto Fujita ◽  
Yuka Kataoka ◽  
Seiji Tobita ◽  
Masayasu Kuwahara ◽  
Naoki Sugimoto
Keyword(s):  
Real Time ◽  
Signal Amplification ◽  
Biomarker Detection ◽  
Détection Signal ◽  
One Step ◽  
Detection Signal

One-Step Enzyme-Free Detection of the miRNA Let-7a via Twin-Stage Signal Amplification

Talanta ◽  
2021 ◽  
pp. 122158
Author(s):  
Jiamei Pu ◽  
Mingbin Liu ◽  
Hongbo Li ◽  
Zhigang Liao ◽  
Weihua Zhao ◽  
...  
Keyword(s):  
Signal Amplification ◽  
One Step

scholarly journals A cooperative-binding split aptamer assay for rapid, specific and ultra-sensitive fluorescence detection of cocaine in saliva

2017 ◽  
Vol 8 (1) ◽  
pp. 131-141 ◽  
Author(s):  
Haixiang Yu ◽  
Juan Canoura ◽  
Bhargav Guntupalli ◽  
Xinhui Lou ◽  
Yi Xiao
Keyword(s):  
Fluorescence Detection ◽  
Signal Amplification ◽  
Rapid Detection ◽  
Fluorescence Assay ◽  
Cooperative Binding ◽  
Binding Mechanism ◽  
One Step ◽  
Aptamer Assay ◽  
Target Binding

A fluorescence assay based on a split aptamer featuring a cooperative-target-binding mechanism performs one-step, rapid detection of as low as 50 nM in 10% saliva without signal amplification.

One-step quantification of salivary exosomes based on combined aptamer recognition and quantum dot signal amplification

2021 ◽  
Vol 171 ◽  
pp. 112733
Author(s):  
Min Wu ◽  
Zhuokun Chen ◽  
Qihui Xie ◽  
Bolin Xiao ◽  
Gang Zhou ◽  
...  
Keyword(s):  
Quantum Dot ◽  
Signal Amplification ◽  
One Step

scholarly journals Hybridization chain reaction enables a unified approach to multiplexed, quantitative, high-resolution immunohistochemistry and in situ hybridization

Development ◽  
2021 ◽  
Vol 148 (22) ◽  
Author(s):  
Maayan Schwarzkopf ◽  
Mike C. Liu ◽  
Samuel J. Schulte ◽  
Rachel Ives ◽  
Naeem Husain ◽  
...  
Keyword(s):  
In Situ Hybridization ◽  
High Resolution ◽  
Signal Amplification ◽  
Brain Slices ◽  
Hybridization Chain Reaction ◽  
Unified Framework ◽  
Chain Reaction ◽  
One Step ◽  
Rna Imaging

ABSTRACT RNA in situ hybridization based on the mechanism of the hybridization chain reaction (HCR) enables multiplexed, quantitative, high-resolution RNA imaging in highly autofluorescent samples, including whole-mount vertebrate embryos, thick brain slices and formalin-fixed paraffin-embedded tissue sections. Here, we extend the benefits of one-step, multiplexed, quantitative, isothermal, enzyme-free HCR signal amplification to immunohistochemistry, enabling accurate and precise protein relative quantitation with subcellular resolution in an anatomical context. Moreover, we provide a unified framework for simultaneous quantitative protein and RNA imaging with one-step HCR signal amplification performed for all target proteins and RNAs simultaneously.

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