Donor–Acceptor-Type Conjugated Polymer-Based Multicolored Drug Carriers with Tunable Aggregation-Induced Emission Behavior for Self-Illuminating Cancer Therapy

2019 ◽  
Vol 11 (45) ◽  
pp. 41853-41861 ◽  
Author(s):  
Ziyu Wang ◽  
Cheng Wang ◽  
Quan Gan ◽  
Yu Cao ◽  
Hong Yuan ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Conjugated Polymer ◽  
Drug Carriers ◽  
Aggregation Induced Emission ◽  
Donor Acceptor ◽  
Emission Behavior

Donor–Acceptor Conjugated Polymer Dots for Tunable Electrochemiluminescence Activated by Aggregation-Induced Emission-Active Moieties

2018 ◽  
Vol 9 (18) ◽  
pp. 5296-5302 ◽  
Author(s):  
Ziyu Wang ◽  
Yaqiang Feng ◽  
Ningning Wang ◽  
Yixiang Cheng ◽  
Yiwu Quan ◽  
...  
Keyword(s):  
Conjugated Polymer ◽  
Aggregation Induced Emission ◽  
Polymer Dots ◽  
Donor Acceptor

Color-tunable AIE-active conjugated polymer nanoparticles as drug carriers for self-indicating cancer therapy via intramolecular FRET mechanism

2018 ◽  
Vol 9 (23) ◽  
pp. 3205-3214 ◽  
Author(s):  
Ziyu Wang ◽  
Cheng Wang ◽  
Yayun Fang ◽  
Hong Yuan ◽  
Yiwu Quan ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Conjugated Polymers ◽  
Conjugated Polymer ◽  
Suzuki Coupling ◽  
Drug Carriers ◽  
Polymer Nanoparticles ◽  
Polymerization Reaction ◽  
Color Tunable ◽  
Conjugated Polymer Nanoparticles ◽  
Coupling Polymerization

In this paper, two novel AIE-active conjugated polymers were synthesized by Pd-catalyzed Suzuki coupling polymerization reaction.

Hyaluronan based Multifunctional Nano-carriers for Combination Cancer Therapy

2020 ◽  
Vol 20 ◽  
Author(s):  
Menghan Gao ◽  
Hong Deng ◽  
Weiqi Zhang
Keyword(s):  
Cancer Therapy ◽  
Combination Therapy ◽  
Cancer Cells ◽  
Drug Loading ◽  
Tumor Therapy ◽  
Drug Carriers ◽  
Functional Sites ◽  
Therapeutic Modalities ◽  
Combination Cancer Therapy ◽  
Targeting Strategy

: Hyaluronan (HA) is a natural linear polysaccharide that has excellent hydrophilicity, biocompatibility, biodegradability, and low immunogenicity, making it one of the most attractive biopolymers used for biomedical researches and applications. Due to the multiple functional sites on HA and its intrinsic affinity for CD44, a receptor highly expressed on various cancer cells, HA has been widely engineered to construct different drug-loading nanoparticles (NPs) for CD44- targeted anti-tumor therapy. When a cocktail of drugs is co-loaded in HA NP, a multifunctional nano-carriers could be obtained, which features as a highly effective and self-targeting strategy to combat the cancers with CD44 overexpression. The HA-based multidrug nano-carriers can be a combination of different drugs, various therapeutic modalities, or the integration of therapy and diagnostics (theranostics). Up to now, there are many types of HA-based multidrug nano-carriers constructed by different formulation strategies including drug co-conjugates, micelles, nano-gels and hybrid NP of HA and so on. This multidrug nano-carrier takes the full advantages of HA as NP matrix, drug carriers and targeting ligand, representing a simplified and biocompatible platform to realize the targeted and synergistic combination therapy against the cancers. In this review, recent progresses about HA-based multidrug nano-carriers for combination cancer therapy are summarized and its potential challenges for translational applications have been discussed.

Carbazole-modified thiazolo[3,2-c][1,3,5,2]oxadiazaborinines exhibiting aggregation-induced emission and mechanofluorochromism

2021 ◽  
Author(s):  
Mykhaylo A. Potopnyk ◽  
Mykola Kravets ◽  
Roman Luboradzki ◽  
Dmytro Volyniuk ◽  
Volodymyr Sashuk ◽  
...  
Keyword(s):  
Solid State ◽  
Fluorescence Properties ◽  
Aggregation Induced Emission ◽  
Donor Acceptor ◽  
Solid State Fluorescence ◽  
Active Donor

Two novel AIE-active donor–acceptor organoboron complexes with a carbazole donor unit are developed and their morphology-dependent solid-state fluorescence properties are established.

scholarly journals Intra-mitochondrial reaction for cancer cell imaging and anti-cancer therapy by aggregation-induced emission

RSC Advances ◽  
2020 ◽  
Vol 10 (71) ◽  
pp. 43383-43388
Author(s):  
Sangpil Kim ◽  
Juhee Kim ◽  
Batakrishna Jana ◽  
Ja-Hyoung Ryu
Keyword(s):  
Cancer Therapy ◽  
Cancer Cell ◽  
Chemical Reactions ◽  
Cell Imaging ◽  
Cellular Function ◽  
Aggregation Induced Emission ◽  
Cancer Cell Imaging ◽  
Anti Cancer

Controlled intracellular chemical reactions to regulate cellular function remain a challenge in biology mimetic systems.

Direction‐Selectable Ultra‐Highly Oriented State of Donor–Acceptor Conjugated Polymer Induced by Slow Bar Coating Process

2021 ◽  
pp. 2100313
Author(s):  
Yuta Yabuuchi ◽  
Yu Minowa ◽  
Hirotake Kajii ◽  
Shusaku Nagano ◽  
Akihiko Fujii ◽  
...  
Keyword(s):  
Conjugated Polymer ◽  
Coating Process ◽  
Donor Acceptor

Synthesis and Characterization of a New Donor–Acceptor Conjugated Polymer and Polymer∕Ag Nanocomposites

2011 ◽  
Author(s):  
M. G. Murali ◽  
D. Udayakumar ◽  
P. Predeep ◽  
Mrinal Thakur ◽  
M. K. Ravi Varma
Keyword(s):  
Conjugated Polymer ◽  
Synthesis And Characterization ◽  
Donor Acceptor

Phototransistors based on a donor–acceptor conjugated polymer with a high response speed

2015 ◽  
Vol 3 (41) ◽  
pp. 10734-10741 ◽  
Author(s):  
Qinghe Wang ◽  
Min Zhu ◽  
Di Wu ◽  
Guobing Zhang ◽  
Xiaohong Wang ◽  
...  
Keyword(s):  
Conjugated Polymer ◽  
Carrier Transport ◽  
Incident Light ◽  
Response Speed ◽  
High Response ◽  
Electron Carrier ◽  
Transport Response ◽  
Donor Acceptor

A D–A polymer phototransistor shows both hole- and electron-carrier transport response to incident light with photoswitching speeds below 14 ms.

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