Influence of Cell Morphology on Mesenchymal Stem Cell Transfection

2018 ◽  
Vol 11 (2) ◽  
pp. 1932-1941 ◽  
Author(s):  
Yingjun Yang ◽  
Xinlong Wang ◽  
Xiaohong Hu ◽  
Naoki Kawazoe ◽  
Yingnan Yang ◽  
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Aline Rattner ◽  
Laurence Vico ◽  
Eric Audouard ◽  
Jean Claude Dumas ◽  
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Biomaterials ◽  
2019 ◽  
Vol 204 ◽  
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Yi-Ting Yeh ◽  
Josh Wei ◽  
Satenick Thorossian ◽  
Katherine Nguyen ◽  
Clarissa Hoffman ◽  
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Gene Therapy ◽  
2008 ◽  
Vol 15 (7) ◽  
pp. 537-544 ◽  
Author(s):  
E Ferreira ◽  
E Potier ◽  
D Logeart-Avramoglou ◽  
S Salomskaite-Davalgiene ◽  
L M Mir ◽  
...  

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Vol 115 (2) ◽  
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Author(s):  
Amy M. Silverstein ◽  
Robert L. Mauck

The meniscus is a crescent shaped fibrocartilage in the knee comprised of a circumferentially aligned collagenous extracellular matrix (ECM) that functions to transmit load and enhance joint stability. The meniscus ECM varies as a function of region, where the inner meniscus is comprised of 70% collagen (60% type II vs. 40% type I), while the outer meniscus contains 80% collagen (99% type I) [1]. Similarly, cells within the inner meniscus are rounder and more ‘chondrocyte-like’, while those in the outer meniscus are elongated and ‘fibroblast-like’ [2]. Injury of the meniscus alters joint loading and hastens the onset of osteoarthritis. As meniscus healing is limited, there exists a need for functional meniscus replacements.


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Dawn M. Elliott ◽  
...  

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