On-Demand Versatile Prodrug Nanomicelle for Tumor-Specific Bioimaging and Photothermal-Chemo Synergistic Cancer Therapy

2018 ◽  
Vol 10 (45) ◽  
pp. 38700-38714 ◽  
Author(s):  
Yujie Su ◽  
Yuan Liu ◽  
Xiangting Xu ◽  
Jianping Zhou ◽  
Lin Xu ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
On Demand

On-demand generation of heat and free radicals for dual cancer therapy using thermal initiator- and gold nanorod-embedded PLGA nanocomplexes

2019 ◽  
Vol 69 ◽  
pp. 405-413 ◽  
Author(s):  
Guru Karthikeyan Thirunavukkarasu ◽  
G.R. Nirmal ◽  
Hwangjae Lee ◽  
Mingyu Lee ◽  
Inkyu Park ◽  
...  
Keyword(s):  
Free Radicals ◽  
Cancer Therapy ◽  
Gold Nanorod ◽  
On Demand

Drug Implants of Hydrogels via Collective Behavior of Microgel Colloids for On-Demand Cancer Therapy

2019 ◽  
Vol 2 (4) ◽  
pp. 1531-1541
Author(s):  
Yitong Wang ◽  
Ling Wang ◽  
Miaomiao Yan ◽  
Lei Feng ◽  
Shuli Dong ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Collective Behavior ◽  
On Demand ◽  
Drug Implants

Stimuli-Responsive NO Release for On-Demand Gas-Sensitized Synergistic Cancer Therapy

2018 ◽  
Vol 57 (28) ◽  
pp. 8383-8394 ◽  
Author(s):  
Wenpei Fan ◽  
Bryant C. Yung ◽  
Xiaoyuan Chen
Keyword(s):  
Cancer Therapy ◽  
Stimuli Responsive ◽  
On Demand ◽  
No Release

Photodynamic therapy-mediated remote control of chemotherapy toward synergistic anticancer treatment

Nanoscale ◽  
2018 ◽  
Vol 10 (30) ◽  
pp. 14554-14562 ◽  
Author(s):  
Yongjuan Li ◽  
Shixian Lv ◽  
Ziyuan Song ◽  
Juanjuan Dang ◽  
Xudong Li ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Remote Control ◽  
Cancer Therapy ◽  
Drug Release ◽  
Stimuli Responsive ◽  
On Demand ◽  
Release Property ◽  
Anticancer Treatment

Stimuli-responsive nanomedicine (NM) with an on-demand drug release property has demonstrated promising utility toward cancer therapy.

Red and NIR Light-Responsive Polymeric Nanocarriers for On-Demand Drug Delivery

2020 ◽  
Vol 27 (23) ◽  
pp. 3877-3887
Author(s):  
Xinyu He ◽  
Xianzhu Yang ◽  
Dongdong Li ◽  
Ziyang Cao
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Drug Release ◽  
Therapeutic Efficacy ◽  
Drug Uptake ◽  
Design Strategies ◽  
Polymeric Nanocarriers ◽  
Normal Tissues ◽  
On Demand ◽  
Nir Light

Red and NIR light-responsive polymeric nanocarriers capable of on-demand drug delivery have gained tremendous attention for their great potential in cancer therapy. Various strategies have been applied to fabricate such nanocarriers, and they have demonstrated significant therapeutic efficacy and minimal toxicity to normal tissues. Here, we will review the current developments in various red and NIR light-responsive polymeric nanocarriers with respect to their use in on-demand drug delivery, including facilitation of drug internalization and boosting of drug release at targeted sites. We summarize their components and design strategies, and highlight the mechanisms by which the photoactivatable variations enhance drug uptake and drug release. We attempt to provide new insights into the fabrication of red and NIR light-responsive polymeric nanocarriers for on-demand drug delivery.

Zwitterionic Polysulfamide Drug Nanogels with Microwave Augmented Tumor Accumulation and On‐Demand Drug Release for Enhanced Cancer Therapy

2020 ◽  
Vol 30 (23) ◽  
pp. 2001832 ◽  
Author(s):  
Shaojun Peng ◽  
Hao Wang ◽  
Wei Zhao ◽  
Yongjie Xin ◽  
Yu Liu ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Drug Release ◽  
On Demand ◽  
Tumor Accumulation

Tumor pH-triggered “charge conversion” nanocarriers with on-demand drug release for precise cancer therapy

2020 ◽  
Vol 8 (40) ◽  
pp. 9351-9361
Author(s):  
Bo-Ai Ma ◽  
Chun-Yang Sun
Keyword(s):  
Photodynamic Therapy ◽  
Cancer Therapy ◽  
Drug Release ◽  
X Ray ◽  
On Demand ◽  
Tumor Ph

The pHe-triggered “charge conversion” nanocarriers were developed for combined X-ray-induced photodynamic therapy (X-PDT) and hypoxia-activated chemotherapy.

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