Preoccupation of Empty Carriers Decreases Endo-/Lysosome Escape and Reduces the Protein Delivery Efficiency of Mesoporous Silica Nanoparticles

2018 ◽  
Vol 10 (6) ◽  
pp. 5340-5347 ◽  
Author(s):  
Wen-Qing Li ◽  
Li-Ping Sun ◽  
Yiqiu Xia ◽  
Sijie Hao ◽  
Gong Cheng ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Protein Delivery ◽  
Mesoporous Silica Nanoparticles ◽  
Delivery Efficiency

Core-Cone Structured Monodispersed Mesoporous Silica Nanoparticles with Ultra-large Cavity for Protein Delivery

Small ◽  
2015 ◽  
Vol 11 (44) ◽  
pp. 5949-5955 ◽  
Author(s):  
Chun Xu ◽  
Meihua Yu ◽  
Owen Noonan ◽  
Jun Zhang ◽  
Hao Song ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Protein Delivery ◽  
Mesoporous Silica Nanoparticles ◽  
Large Cavity

Bioinspired Diselenide-Bridged Mesoporous Silica Nanoparticles for Dual-Responsive Protein Delivery

2018 ◽  
Vol 30 (29) ◽  
pp. 1801198 ◽  
Author(s):  
Dan Shao ◽  
Mingqiang Li ◽  
Zheng Wang ◽  
Xiao Zheng ◽  
Yeh-Hsing Lao ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Protein Delivery ◽  
Mesoporous Silica Nanoparticles ◽  
Dual Responsive

scholarly journals Protein Delivery: Bioinspired Diselenide-Bridged Mesoporous Silica Nanoparticles for Dual-Responsive Protein Delivery (Adv. Mater. 29/2018)

2018 ◽  
Vol 30 (29) ◽  
pp. 1870209 ◽  
Author(s):  
Dan Shao ◽  
Mingqiang Li ◽  
Zheng Wang ◽  
Xiao Zheng ◽  
Yeh-Hsing Lao ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Protein Delivery ◽  
Mesoporous Silica Nanoparticles ◽  
Dual Responsive

scholarly journals Smart Mesoporous Silica Nanoparticles for Protein Delivery

Nanomaterials ◽  
2019 ◽  
Vol 9 (4) ◽  
pp. 511 ◽  
Author(s):  
Hai-Jun Liu ◽  
Peisheng Xu
Keyword(s):  
Thermal Stability ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Surface Functionalization ◽  
Targeted Delivery ◽  
Protein Delivery ◽  
Mesoporous Silica Nanoparticles ◽  
Loading Capacity ◽  
Factors Affecting ◽  
The Past

Mesoporous silica nanoparticles (MSN) have attracted a lot of attention during the past decade which is attributable to their versatile and high loading capacity, easy surface functionalization, excellent biocompatibility, and great physicochemical and thermal stability. In this review, we discuss the factors affecting the loading of protein into MSN and general strategies for targeted delivery and controlled release of proteins with MSN. Additionally, we also give an outlook for the remaining challenges in the clinical translation of protein-loaded MSNs.

Mesoporous silica nanoparticles for enhancing the delivery efficiency of immunostimulatory DNA drugs

2014 ◽  
Vol 43 (13) ◽  
pp. 5142-5150 ◽  
Author(s):  
Cuilian Tao ◽  
Yufang Zhu ◽  
Yi Xu ◽  
Min Zhu ◽  
Hiromi Morita ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Drug Delivery System ◽  
Delivery System ◽  
Mesoporous Silica Nanoparticles ◽  
Double Stranded Dna ◽  
Delivery Efficiency ◽  
Immunostimulatory Dna

A potential immunostimulatory double-stranded DNA (dsDNA) drug delivery system has been designed for enhancing the delivery efficiency.

scholarly journals Biocompatibility, Biodistribution, and Drug-Delivery Efficiency of Mesoporous Silica Nanoparticles for Cancer Therapy in Animals

Small ◽  
2010 ◽  
Vol 6 (16) ◽  
pp. 1794-1805 ◽  
Author(s):  
Jie Lu ◽  
Monty Liong ◽  
Zongxi Li ◽  
Jeffrey I. Zink ◽  
Fuyuhiko Tamanoi
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Delivery Efficiency
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