Core-Cone Structured Monodispersed Mesoporous Silica Nanoparticles with Ultra-large Cavity for Protein Delivery

Small ◽  
2015 ◽  
Vol 11 (44) ◽  
pp. 5949-5955 ◽  
Author(s):  
Chun Xu ◽  
Meihua Yu ◽  
Owen Noonan ◽  
Jun Zhang ◽  
Hao Song ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Protein Delivery ◽  
Mesoporous Silica Nanoparticles ◽  
Large Cavity

Bioinspired Diselenide-Bridged Mesoporous Silica Nanoparticles for Dual-Responsive Protein Delivery

2018 ◽  
Vol 30 (29) ◽  
pp. 1801198 ◽  
Author(s):  
Dan Shao ◽  
Mingqiang Li ◽  
Zheng Wang ◽  
Xiao Zheng ◽  
Yeh-Hsing Lao ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Protein Delivery ◽  
Mesoporous Silica Nanoparticles ◽  
Dual Responsive

scholarly journals Protein Delivery: Bioinspired Diselenide-Bridged Mesoporous Silica Nanoparticles for Dual-Responsive Protein Delivery (Adv. Mater. 29/2018)

2018 ◽  
Vol 30 (29) ◽  
pp. 1870209 ◽  
Author(s):  
Dan Shao ◽  
Mingqiang Li ◽  
Zheng Wang ◽  
Xiao Zheng ◽  
Yeh-Hsing Lao ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Protein Delivery ◽  
Mesoporous Silica Nanoparticles ◽  
Dual Responsive

scholarly journals Smart Mesoporous Silica Nanoparticles for Protein Delivery

Nanomaterials ◽  
2019 ◽  
Vol 9 (4) ◽  
pp. 511 ◽  
Author(s):  
Hai-Jun Liu ◽  
Peisheng Xu
Keyword(s):  
Thermal Stability ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Surface Functionalization ◽  
Targeted Delivery ◽  
Protein Delivery ◽  
Mesoporous Silica Nanoparticles ◽  
Loading Capacity ◽  
Factors Affecting ◽  
The Past

Mesoporous silica nanoparticles (MSN) have attracted a lot of attention during the past decade which is attributable to their versatile and high loading capacity, easy surface functionalization, excellent biocompatibility, and great physicochemical and thermal stability. In this review, we discuss the factors affecting the loading of protein into MSN and general strategies for targeted delivery and controlled release of proteins with MSN. Additionally, we also give an outlook for the remaining challenges in the clinical translation of protein-loaded MSNs.

Recent Advances in Application of Azobenzenes Grafted on Mesoporous Silica Nanoparticles in Controlled Drug Delivery Systems Using Light as External Stimulus

2020 ◽  
Vol 20 (11) ◽  
pp. 1001-1016
Author(s):  
Sandra Ramírez-Rave ◽  
María Josefa Bernad-Bernad ◽  
Jesús Gracia-Mora ◽  
Anatoly K. Yatsimirsky
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Drug Delivery Systems ◽  
Mesoporous Silica Nanoparticles ◽  
High Surface ◽  
Delivery Systems ◽  
Surface Reactivity ◽  
External Stimulus ◽  
Recent Advances

Hybrid materials based on Mesoporous Silica Nanoparticles (MSN) have attracted plentiful attention due to the versatility of their chemistry, and the field of Drug Delivery Systems (DDS) is not an exception. MSN present desirable biocompatibility, high surface area values, and a well-studied surface reactivity for tailoring a vast diversity of chemical moieties. Particularly important for DDS applications is the use of external stimuli for drug release. In this context, light is an exceptional alternative due to its high degree of spatiotemporal precision and non-invasive character, and a large number of promising DDS based on photoswitchable properties of azobenzenes have been recently reported. This review covers the recent advances in design of DDS using light as an external stimulus mostly based on literature published within last years with an emphasis on usually overlooked underlying chemistry, photophysical properties, and supramolecular complexation of azobenzenes.

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