Efficient Enrichment and Self-Assembly of Hybrid Nanoparticles into Removable and Magnetic SERS Substrates for Sensitive Detection of Environmental Pollutants

2017 ◽  
Vol 9 (8) ◽  
pp. 7472-7480 ◽  
Author(s):  
Siying Tang ◽  
Yong Li ◽  
Hao Huang ◽  
Penghui Li ◽  
Zhinan Guo ◽  
...  
Keyword(s):  
Self Assembly ◽  
Environmental Pollutants ◽  
Sensitive Detection ◽  
Hybrid Nanoparticles ◽  
Sers Substrates

Plasmonics tunable Ag-coated gold nanorods arrays as reusable SERS substrates for multiplexed antibiotics detection

2021 ◽  
Author(s):  
Xiaoya Peng ◽  
Dan Li ◽  
Yuanting Li ◽  
Haibo Xing ◽  
Wei Deng
Keyword(s):  
Gold Nanorods ◽  
Self Assembly ◽  
Aqueous Media ◽  
Antibiotic Residues ◽  
Sers Substrates ◽  
Antibiotics Detection ◽  
Robust Strategies

Antibiotic contaminants in aqueous media pose serious threat to human and ecological environments. Therefore, it is necessary to develop robust strategies to detect antibiotic residues. For this purpose, a self-assembly...

scholarly journals Dual Targeting of Cancer Cells and MMPs with Self-Assembly Hybrid Nanoparticles for Combination Therapy in Combating Cancer

Pharmaceutics ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 1990
Author(s):  
Kai Zhang ◽  
Jingjing Li ◽  
Xiaofei Xin ◽  
Xiaoqing Du ◽  
Di Zhao ◽  
...  
Keyword(s):  
T Cells ◽  
Cancer Cells ◽  
Self Assembly ◽  
Chemotherapeutic Agents ◽  
Hybrid Nanoparticles ◽  
Control Group ◽  
Hyperthermia Treatment ◽  
Immune Modulators ◽  
Dual Targeting

The co-delivery of chemotherapeutic agents and immune modulators to their targets remains to be a great challenge for nanocarriers. Here, we developed a hybrid thermosensitive nanoparticle (TMNP) which could co-deliver paclitaxel-loaded transferrin (PTX@TF) and marimastat-loaded thermosensitive liposomes (MMST/LTSLs) for the dual targeting of cancer cells and the microenvironment. TMNPs could rapidly release the two payloads triggered by the hyperthermia treatment at the site of tumor. The released PTX@TF entered cancer cells via transferrin-receptor-mediated endocytosis and inhibited the survival of tumor cells. MMST was intelligently employed as an immunomodulator to improve immunotherapy by inhibiting matrix metalloproteinases to reduce chemokine degradation and recruit T cells. The TMNPs promoted the tumor infiltration of CD3+ T cells by 2-fold, including memory/effector CD8+ T cells (4.2-fold) and CD4+ (1.7-fold), but not regulatory T cells. Our in vivo anti-tumor experiment suggested that TMNPs possessed the highest tumor growth inhibitory rate (80.86%) compared with the control group. We demonstrated that the nanoplatform could effectively inhibit the growth of tumors and enhance T cell recruitment through the co-delivery of paclitaxel and marimastat, which could be a promising strategy for the combination of chemotherapy and immunotherapy for cancer treatment.

Size-Dependent Self-Assembly of Anisotropic Silica-Coated Hybrid Nanoparticles

2015 ◽  
Vol 216 (21) ◽  
pp. 2070-2079 ◽  
Author(s):  
Diego Estupiñán ◽  
Markus B. Bannwarth ◽  
Katharina Landfester ◽  
Daniel Crespy
Keyword(s):  
Self Assembly ◽  
Hybrid Nanoparticles ◽  
Size Dependent

Dye encapsulated zinc-based metal-organic framework as a dual-emission sensor for highly sensitive detection of antibiotics

2021 ◽  
Author(s):  
Kang Wang ◽  
Yuhan Duan ◽  
Jiajing Chen ◽  
Haiying Wang ◽  
Hui-Yan Liu
Keyword(s):  
Self Assembly ◽  
Metal Organic Framework ◽  
Sensitive Detection ◽  
Dual Emission ◽  
Highly Sensitive ◽  
Metal Organic ◽  
Highly Sensitive Detection ◽  
Organic Framework

Self-assembly of two Zn-MOFs, [Zn2L(DMF)3]•H2O•5DMF (1) and [Zn2L(H2O)2]•4H2O•3DMF (2) were achieved with an amide-functionalized tetracarboxylate ligand under similar conditions. Incorporated amide groups make the tetratopic linkers exhibit different configurations, tetrahedron...

Self-assembly of various silver nanocrystals on PmPD/PAN nanofibers as a high-performance 3D SERS substrate

The Analyst ◽  
2015 ◽  
Vol 140 (16) ◽  
pp. 5707-5715 ◽  
Author(s):  
Peng Jia ◽  
Bing Cao ◽  
Jianqiang Wang ◽  
Jin Qu ◽  
Yuxuan Liu ◽  
...  
Keyword(s):  
Self Assembly ◽  
High Performance ◽  
Sers Substrate ◽  
Sers Substrates ◽  
Highly Sensitive ◽  
Nanofiber Mats ◽  
Pan Nanofiber

The AgNCs (AgNPs, AgNTs and AgNDs) decorated-PmPD/PAN nanofiber mats were obtained as highly sensitive 3D SERS substrates.

Paclitaxel-induced formation of 3D nanocrystal superlattices within injectable protein-based hybrid nanoparticles

2018 ◽  
Vol 54 (82) ◽  
pp. 11586-11589
Author(s):  
Jeong Yu Lee ◽  
Ho Yeon Son ◽  
Jae Chul Park ◽  
Jongnam Park ◽  
Yoon Sung Nam
Keyword(s):  
Polyethylene Glycol ◽  
Iron Oxide ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Self Assembly ◽  
Three Dimensional ◽  
Superparamagnetic Iron Oxide ◽  
Hybrid Nanoparticles ◽  
Nanocrystal Superlattices

Self-assembly of monodisperse superparamagnetic iron oxide nanocrystals into a close-packed, three-dimensional (3D) superlattice is designed within cross-linked protein-based nanoparticles composed of human serum albumin and polyethylene glycol.

Polymer induced one-step interfacial self-assembly method for the fabrication of flexible, robust and free-standing SERS substrates for rapid on-site detection of pesticide residues

Nanoscale ◽  
2019 ◽  
Vol 11 (27) ◽  
pp. 12829-12836 ◽  
Author(s):  
Peng Wu ◽  
Lu-Bin Zhong ◽  
Qing Liu ◽  
Xi Zhou ◽  
Yu-Ming Zheng
Keyword(s):  
Pesticide Residue ◽  
Self Assembly ◽  
Pesticide Residues ◽  
Free Standing ◽  
Sers Substrates ◽  
Residue Detection ◽  
Assembly Method ◽  
One Step

A polymer induced one-step interfacial self-assembly method was developed to fabricate flexible, robust and free-standing SERS substrates for rapid pesticide residue detection.

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