Core–Shell Chitosan Microcapsules for Programmed Sequential Drug Release

2016 ◽  
Vol 8 (16) ◽  
pp. 10524-10534 ◽  
Author(s):  
Xiu-Lan Yang ◽  
Xiao-Jie Ju ◽  
Xiao-Ting Mu ◽  
Wei Wang ◽  
Rui Xie ◽  
...  
Keyword(s):  
Drug Release ◽  
Core Shell ◽  
Sequential Drug Release

Polymer-controlled core–shell nanoparticles: a novel strategy for sequential drug release

RSC Advances ◽  
2014 ◽  
Vol 4 (57) ◽  
pp. 30430-30439 ◽  
Author(s):  
Yang Cao ◽  
Bochu Wang ◽  
Yazhou Wang ◽  
Deshuai Lou
Keyword(s):  
Drug Release ◽  
Plga Nanoparticles ◽  
Therapeutic Agents ◽  
Core Shell ◽  
Shell Nanoparticles ◽  
Miscible Liquids ◽  
Novel Strategy ◽  
Core Shell Nanoparticles ◽  
Sequential Drug Release ◽  
Coaxial Electrospray

Immiscible and miscible liquids were utilized to fabricate PVP/PLGA and PCL/PLGA nanoparticles with a distinct core–shell structure by coaxial electrospray. Two different sequential drug release profiles from different nanoparticles were observed. The melanoma cells and endothelial cells can be sequentially targeted and killed by therapeutic agents released from nanoparticles.

Core–Shell Distinct Nanodrug Showing On-Demand Sequential Drug Release To Act on Multiple Cell Types for Synergistic Anticancer Therapy

ACS Nano ◽  
2019 ◽  
Vol 13 (6) ◽  
pp. 7036-7049 ◽  
Author(s):  
Jinsheng Huang ◽  
Yongmin Xu ◽  
Hong Xiao ◽  
Zecong Xiao ◽  
Yu Guo ◽  
...  
Keyword(s):  
Drug Release ◽  
Cell Types ◽  
Anticancer Therapy ◽  
Core Shell ◽  
On Demand ◽  
Multiple Cell ◽  
Sequential Drug Release

scholarly journals Multi-Functional Core-Shell Nanofibers for Wound Healing

Nanomaterials ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1546
Author(s):  
Zhen Li ◽  
Shunqi Mei ◽  
Yajie Dong ◽  
Fenghua She ◽  
Puwang Li ◽  
...  
Keyword(s):  
Wound Healing ◽  
Growth Factors ◽  
Drug Release ◽  
Release Rate ◽  
Healing Process ◽  
Wound Healing Process ◽  
Core Shell ◽  
High Production Rate ◽  
Centrifugal Spinning ◽  
Multiple Drugs

Core-shell nanofibers have great potential for bio-medical applications such as wound healing dressings where multiple drugs and growth factors are expected to be delivered at different healing phases. Compared to monoaxial nanofibers, core-shell nanofibers can control the drug release profile easier, providing sustainable and effective drugs and growth factors for wound healing. However, it is challenging to produce core-shell structured nanofibers with a high production rate at low energy consumption. Co-axial centrifugal spinning is an alternative method to address the above limitations to produce core-shell nanofibers effectively. In this study, a co-axial centrifugal spinning device was designed and assembled to produce core-shell nanofibers for controlling the release rate of ibuprofen and hEGF in inflammation and proliferation phases during the wound healing process. Core-shell structured nanofibers were confirmed by TEM. This work demonstrated that the co-axial centrifugal spinning is a high productivity process that can produce materials with a 3D environment mimicking natural tissue scaffold, and the specific drug can be loaded into different layers to control the drug release rate to improve the drug efficiency and promote wound healing.

Up-Conversion Cell Imaging and pH-Induced Thermally Controlled Drug Release from NaYF4:Yb3+/Er3+@Hydrogel Core–Shell Hybrid Microspheres

ACS Nano ◽  
2012 ◽  
Vol 6 (4) ◽  
pp. 3327-3338 ◽  
Author(s):  
Yunlu Dai ◽  
Ping’an Ma ◽  
Ziyong Cheng ◽  
Xiaojiao Kang ◽  
Xiao Zhang ◽  
...  
Keyword(s):  
Drug Release ◽  
Cell Imaging ◽  
Controlled Drug Release ◽  
Core Shell

Fabrication and characterization of monodisperse PLGA–alginate core–shell microspheres with monodisperse size and homogeneous shells for controlled drug release

2013 ◽  
Vol 9 (7) ◽  
pp. 7410-7419 ◽  
Author(s):  
Jun Wu ◽  
Tiantian Kong ◽  
Kelvin Wai Kwok Yeung ◽  
Ho Cheung Shum ◽  
Kenneth Man Chee Cheung ◽  
...  
Keyword(s):  
Drug Release ◽  
Controlled Drug Release ◽  
Core Shell ◽  
Fabrication And Characterization

scholarly journals ATRP-based synthesis of a pH-sensitive amphiphilic block polymer and its self-assembled micelles with hollow mesoporous silica as DOX carriers for controlled drug release

RSC Advances ◽  
2021 ◽  
Vol 11 (48) ◽  
pp. 29986-29996
Author(s):  
Xiuxiu Qi ◽  
Hongmei Yan ◽  
Yingxue Li
Keyword(s):  
Controlled Release ◽  
Drug Release ◽  
Self Assembly ◽  
Drug Loading ◽  
Controlled Drug Release ◽  
Ph Sensitive ◽  
Core Shell ◽  
Assembly Process ◽  
Block Polymer ◽  
Hollow Mesoporous Silica

A pH-sensitive core–shell nanoparticle (HMS@C18@PSDMA-b-POEGMA) was developed via a self-assembly process as the carrier of anticancer drug doxorubicin (DOX) for drug loading and controlled release.

Multifunctional core-shell silica microspheres and their performance in self-carrier decomposition, sustained drug release and fluorescent bioimaging

2018 ◽  
Vol 263 ◽  
pp. 148-156 ◽  
Author(s):  
Yamina Ait Mehdi ◽  
Asma Itatahine ◽  
Meriem Fizir ◽  
Deli Xiao ◽  
Pierre Dramou ◽  
...  
Keyword(s):  
Drug Release ◽  
Core Shell ◽  
Silica Microspheres ◽  
Sustained Drug Release

Pegylated CdSe/ZnS core/shell nanoparticles for controlled drug release

2019 ◽  
Vol 243 ◽  
pp. 115-124 ◽  
Author(s):  
Shivani Bharti ◽  
Gurvir Kaur ◽  
Shikha Gupta ◽  
S.K. Tripathi
Keyword(s):  
Drug Release ◽  
Controlled Drug Release ◽  
Core Shell ◽  
Shell Nanoparticles ◽  
Core Shell Nanoparticles

scholarly journals Correction to Supramolecular Drug–Drug Complex Vesicles Enable Sequential Drug Release for Enhanced Combination Therapy

2020 ◽  
Vol 12 (39) ◽  
pp. 44382-44382
Author(s):  
Chengfei Liu ◽  
Chunpu Li ◽  
Cui Pang ◽  
Muqiong Li ◽  
Huixin Li ◽  
...  
Keyword(s):  
Drug Release ◽  
Combination Therapy ◽  
Sequential Drug Release ◽  
Drug Complex

Folate-targeting magnetic core–shell nanocarriers for selective drug release and imaging

2012 ◽  
Vol 430 (1-2) ◽  
pp. 342-349 ◽  
Author(s):  
Hanjie Wang ◽  
Sheng Wang ◽  
Zhenyu Liao ◽  
Peiqi Zhao ◽  
Wenya Su ◽  
...  
Keyword(s):  
Drug Release ◽  
Magnetic Core ◽  
Core Shell ◽  
Folate Targeting
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