Excavating the Role of Aloe Vera Wrapped Mesoporous Hydroxyapatite Frame Ornamentation in Newly Architectured Polyurethane Scaffolds for Osteogenesis and Guided Bone Regeneration with Microbial Protection

2016 ◽  
Vol 8 (9) ◽  
pp. 5941-5960 ◽  
Author(s):  
M. Selvakumar ◽  
Harpreet Singh Pawar ◽  
Nimmy K. Francis ◽  
Bodhisatwa Das ◽  
Santanu Dhara ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Aloe Vera ◽  
Guided Bone Regeneration

The Role of Bone Decortication in Enhancing the Results of Guided Bone Regeneration: A Literature Review

2009 ◽  
Vol 80 (2) ◽  
pp. 175-189 ◽  
Author(s):  
G. Greenstein ◽  
B. Greenstein ◽  
J. Cavallaro ◽  
D. Tarnow
Keyword(s):  
Literature Review ◽  
Bone Regeneration ◽  
Guided Bone Regeneration

scholarly journals Improvement of the Physical Properties of Guided Bone Regeneration Membrane from Porcine Pericardium by Polyphenols-Rich Pomace Extract

Materials ◽  
2019 ◽  
Vol 12 (16) ◽  
pp. 2564 ◽  
Author(s):  
Nazario Russo ◽  
Clara Cassinelli ◽  
Elisa Torre ◽  
Marco Morra ◽  
Giorgio Iviglia
Keyword(s):  
Physical Properties ◽  
Bone Regeneration ◽  
Enzymatic Degradation ◽  
Guided Bone Regeneration ◽  
Mechanical Stiffness ◽  
Infra Red ◽  
Space Maintenance ◽  
The One ◽  
Porcine Pericardium

To achieve optimal performances, guided bone regeneration membranes should have several properties, in particular, proper stiffness and tear resistance for space maintenance, appropriate resorption time, and non-cytotoxic effect. In this work, polyphenol-rich pomace extract (PRPE), from a selected grape variety (Nebbiolo), rich in proanthocyanidins and flavonols (e.g., quercetin), was used as a rich source of polyphenols, natural collagen crosslinkers, to improve the physical properties of the porcine pericardium membrane. The incorporation of polyphenols in the collagen network of the membrane was clearly identified by infra-red spectroscopy through the presence of a specific peak between 1360–1380 cm−1. Polyphenols incorporated into the pericardium membrane bind to collagen with high affinity and reduce enzymatic degradation by 20% compared to the native pericardium. The release study shows a release of active molecules from the membrane, suggesting a possible use in patients affected by periodontitis, considering the role of polyphenols in the control of this pathology. Mechanical stiffness is increased making the membrane easier to handle. Young’s modulus of pericardium treated with PRPE was three-fold higher than the one measured on native pericardium. Tear and suture retention strength measurement suggest favorable properties in the light of clinical practice requirements.

The Role of Two Different Collagen Membranes for Dehiscence Defect Around Implants in Humans

2015 ◽  
Vol 41 (4) ◽  
pp. 445-448 ◽  
Author(s):  
Dong-Woon Lee ◽  
Kyeong-Taek Kim ◽  
Yon-Soo Joo ◽  
Mi-Kyung Yoo ◽  
Jeoung-A Yu ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Guided Bone Regeneration ◽  
Allogenic Bone ◽  
The Mean ◽  
Collagen Membranes ◽  
Dehiscence Defect ◽  
Result Analysis ◽  
Bone Particles

The aim of this study was to elucidate the role of 2 types of collagen membranes (cross-linked vs noncross-linked) used in conjunction with autogenous or allogenic bone followed by xenogeneic bone particles for dehiscence defect around implants in humans. Experimental groups were divided into 2 groups: Group CL (cross-linked, Ossix Plus, n = 24 implants, 16 patients) and Group NCL (noncross-linked, Bio-Gide, n = 25 implants, 18 patients). At the time of implant insertion and uncovery surgery, measurements of the dehiscence bony height, width, and surface area were made. Before applying the membrane to defects, guided bone regeneration was performed. Because it is difficult to measure the degree of exposure, early exposed cases were excluded from the result analysis. The mean percentage gain of the dehiscence defect and the mean marginal bone reduction value of follow-up radiograph did not show statistically significant differences between the 2 groups. Both membranes exhibited satisfactory results on dehiscence defects. As a result, our authors concluded the success of guided bone regeneration was performed simultaneously for dehiscence defects around the implant, regardless whether collagen membranes were cross-linked or noncross-linked.

The role of rhFGF-2 soaked polymer membrane for enhancement of guided bone regeneration

2017 ◽  
Vol 29 (7-9) ◽  
pp. 825-843 ◽  
Author(s):  
Sang-Hoon Lee ◽  
Young-Bum Park ◽  
Hong-Seok Moon ◽  
June-Sung Shim ◽  
Han-Sung Jung ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Guided Bone Regeneration ◽  
Polymer Membrane

scholarly journals The Role of Blood Clot in Guided Bone Regeneration: Biological Considerations and Clinical Applications with Titanium Foil

Materials ◽  
2021 ◽  
Vol 14 (21) ◽  
pp. 6642
Author(s):  
Lucio Milillo ◽  
Fabrizio Cinone ◽  
Federico Lo Presti ◽  
Dorina Lauritano ◽  
Massimo Petruzzi
Keyword(s):  
Bone Regeneration ◽  
Blood Clot ◽  
Strength Properties ◽  
Guided Bone Regeneration ◽  
Titanium Foil ◽  
Filler Materials ◽  
Clinical Settings ◽  
Fundamental Properties ◽  
Blood Clots

In Guided Bone Regeneration (GBR) materials and techniques are essential to achieve the expected results. Thanks to their properties, blood clots induce bone healing, maturation, differentiation and organization. The preferred material to protect the clot in Guided Bone Regeneration is the titanium foil, as it can be shaped according to the bone defect. Furthermore, its exposition in the oral cavity does not impair the procedure. We report on five clinical cases in order to explain the management of blood clots in combination with titanium foil barriers in different clinical settings. Besides being the best choice to protect the clot, the titanium foil represents an excellent barrier that is useful in GBR due to its biocompatibility, handling, and mechanical strength properties. The clot alone is the best natural scaffold to obtain the ideal bone quality and avoid the persistence of not-resorbed granules of filler materials in the newly regenerated bone. Even though clot contraction still needs to be improved, as it impacts the volume of the regenerated bone, future studies in GBR should be inspired by the clot and its fundamental properties.

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