Swelling-Induced Information Camouflage and Optical Decryption on a Transparent Recoverable Hydrogel Surface

2022 ◽  
Author(s):  
Mengda Xu ◽  
Yan Miao ◽  
Xiaxin Qiu ◽  
Xiaodong Song ◽  
Qiuhua Zhao ◽  
...  
Keyword(s):  
Hydrogel Surface

The mechanics of single cross-links which mediate cell attachment at a hydrogel surface

Nanoscale ◽  
2019 ◽  
Vol 11 (24) ◽  
pp. 11596-11604 ◽  
Author(s):  
Arzu Çolak ◽  
Bin Li ◽  
Johanna Blass ◽  
Kaloian Koynov ◽  
Aranzazu del Campo ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Cell Adhesion ◽  
Cell Attachment ◽  
Force Spectroscopy ◽  
Single Cross ◽  
Mediate Cell Adhesion ◽  
Cross Links ◽  
Hydrogel Surface ◽  
Mediate Cell

The mechanical properties of single cross-links which mediate cell adhesion are explored by force spectroscopy.

scholarly journals 3D-printable zwitterionic nano-composite hydrogel system for biomedical applications

2020 ◽  
Vol 11 ◽  
pp. 204173142096729
Author(s):  
Nathalie Sällström ◽  
Andrew Capel ◽  
Mark P Lewis ◽  
Daniel S Engstrøm ◽  
Simon Martin
Keyword(s):  
Mechanical Properties ◽  
Biomedical Applications ◽  
Culture Medium ◽  
Careful Selection ◽  
Nano Composite ◽  
Significant Difference ◽  
Nano Clay ◽  
Hydrogel Surface ◽  
Selection Of ◽  
Hydrogel System

Herein, the cytotoxicity of a novel zwitterionic sulfobetaine hydrogel system with a nano-clay crosslinker has been investigated. We demonstrate that careful selection of the composition of the system (monomer to Laponite content) allows the material to be formed into controlled shapes using an extrusion based additive manufacturing technique with the ability to tune the mechanical properties of the product. Moreover, the printed structures can support their own weight without requiring curing during printing which enables the use of a printing-then-curing approach. Cell culture experiments were conducted to evaluate the neural cytotoxicity of the developed hydrogel system. Cytotoxicity evaluations were conducted on three different conditions; a control condition, an indirect condition (where the culture medium used had been in contact with the hydrogel to investigate leaching) and a direct condition (cells growing directly on the hydrogel). The result showed no significant difference in cell viability between the different conditions and cells were also found to be growing on the hydrogel surface with extended neurites present.

scholarly journals Biocompatibility of Nanocellulose-Reinforced PVA Hydrogel with Human Corneal Epithelial Cells for Ophthalmic Applications

2019 ◽  
Vol 10 (3) ◽  
pp. 35 ◽  
Author(s):  
Tummala ◽  
Lopes ◽  
Mihranyan ◽  
Ferraz
Keyword(s):  
Epithelial Cells ◽  
Cell Viability ◽  
Protein Adsorption ◽  
Direct Contact ◽  
Corneal Epithelial Cell ◽  
Corneal Epithelial Cells ◽  
Corneal Epithelial ◽  
Human Corneal Epithelial Cells ◽  
Hydrogel Surface

Transparent composite hydrogel in the form of a contact lens made from poly(vinyl alcohol) (PVA) and cellulose nanocrystals (CNCs) was subjected to in vitro biocompatibility evaluation with human corneal epithelial cells (HCE-2 cells). The cell response to direct contact with the hydrogels was investigated by placing the samples on top of confluent cell layers and evaluating cell viability, morphology, and cell layer integrity subsequent to 24 h culture and removal of the hydrogels. To further characterize the lens–cell interactions, HCE-2 cells were seeded on the hydrogels, with and without simulated tear fluid (STF) pre-conditioning, and cell viability and morphology were evaluated. Furthermore, protein adsorption on the hydrogel surface was investigated by incubating the materials with STF, followed by protein elution and quantification. The hydrogel material was found to have affinity towards protein adsorption, most probably due to the interactions between the positively charged lysozyme and the negatively charged CNCs embedded in the PVA matrix. The direct contact experiment demonstrated that the physical presence of the lenses did not affect corneal epithelial cell monolayers in terms of integrity nor cell metabolic activity. Moreover, it was found that viable corneal cells adhered to the hydrogel, showing the typical morphology of epithelial cells and that such response was not influenced by the STF pre-conditioning of the hydrogel surface. The results of the study confirm that PVA-CNC hydrogel is a promising ophthalmic biomaterial, motivating future in vitro and in vivo biocompatibility studies.

Coatings with a self-generating hydrogel surface for antifouling

Polymer ◽  
2011 ◽  
Vol 52 (17) ◽  
pp. 3738-3744 ◽  
Author(s):  
Laiyong Xie ◽  
Fei Hong ◽  
Chuanxin He ◽  
Chunfeng Ma ◽  
Jianhong Liu ◽  
...  
Keyword(s):  
Hydrogel Surface
Sign in / Sign up

Export Citation Format

Share Document