Rodlike Particles of Polydopamine-CdTe Quantum Dots: An Actuator As a Photothermal Agent and Reactive Oxygen Species-Generating Nanoplatform for Cancer Therapy

2021 ◽  
Vol 13 (36) ◽  
pp. 42357-42369
Author(s):  
Greter A. Ortega ◽  
S. Del Sol-Fernández ◽  
Yadileiny Portilla ◽  
Enrique Cedeño ◽  
Edilso Reguera ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Quantum Dots ◽  
Cancer Therapy ◽  
Reactive Oxygen ◽  
Cdte Quantum Dots ◽  
Oxygen Species ◽  
Rodlike Particles

scholarly journals Conducting polymer nanoparticles for targeted cancer therapy

RSC Advances ◽  
2015 ◽  
Vol 5 (47) ◽  
pp. 37943-37956 ◽  
Author(s):  
Mona Doshi ◽  
Marissa Krienke ◽  
Saeid Khederzadeh ◽  
Henry Sanchez ◽  
Alicja Copik ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Cancer Therapy ◽  
Conducting Polymer ◽  
Targeted Delivery ◽  
Reactive Oxygen ◽  
Polymer Nanoparticles ◽  
Oxygen Species ◽  
Targeted Cancer Therapy ◽  
Fluorescence Bioimaging

Functionalized conducting polymer nanoparticles allow for targeted delivery, tracking by fluorescence bioimaging, and therapeutics through formation of reactive oxygen species.

A glucose-depleting silica nanosystem for increasing reactive oxygen species and scavenging glutathione in cancer therapy

2019 ◽  
Vol 55 (89) ◽  
pp. 13374-13377 ◽  
Author(s):  
Wee Kong Ong ◽  
Deblin Jana ◽  
Yanli Zhao
Keyword(s):  
Reactive Oxygen Species ◽  
Hydrogen Peroxide ◽  
Cancer Therapy ◽  
Reactive Oxygen ◽  
Species Level ◽  
Reactive Oxygen Species Level ◽  
Oxygen Species ◽  
Anticancer Treatment ◽  
Intracellular Glucose

A novel silica nanosystem is fabricated to convert intracellular glucose to hydrogen peroxide for enhancing reactive oxygen species level and triggering p-quinomethane release to scavenge glutathione, achieving synergistic anticancer treatment.

scholarly journals Ultrasound-induced reactive oxygen species generation and mitochondria-specific damage by sonodynamic agent/metal ion-doped mesoporous silica

RSC Advances ◽  
2019 ◽  
Vol 9 (68) ◽  
pp. 39924-39931 ◽  
Author(s):  
Kecan Lin ◽  
Ziguo Lin ◽  
Yujie Li ◽  
Youshi Zheng ◽  
Da Zhang
Keyword(s):  
Reactive Oxygen Species ◽  
Tumor Microenvironment ◽  
Cancer Therapy ◽  
Mesoporous Silica ◽  
Metal Ion ◽  
Reactive Oxygen Species Generation ◽  
Reactive Oxygen ◽  
Oxygen Species

Herein, we design tumor microenvironment specific active nano sono-chemodynamic agent for synergistic photodynamic–chemodynamic cancer therapy.

scholarly journals Integration of intracellular telomerase monitoring by electrochemiluminescence technology and targeted cancer therapy by reactive oxygen species

2017 ◽  
Vol 8 (12) ◽  
pp. 8025-8029 ◽  
Author(s):  
Huairong Zhang ◽  
Binxiao Li ◽  
Zhaomei Sun ◽  
Hong Zhou ◽  
Shusheng Zhang
Keyword(s):  
Reactive Oxygen Species ◽  
Cancer Therapy ◽  
Cancer Cells ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Targeted Cancer Therapy ◽  
High Efficacy

ROS and polyluminol–Pt NPs were used for intracellular telomerase detection and to induce apoptosis in HL-60 cancer cells with high efficacy.

THE ROLES OF PHOTOLUMINESCENT QUANTUM DOTS IN GENERATION OR DETECTION OF REACTIVE OXYGEN SPECIES: CULPRITS OR DETECTIVES?

COSMOS ◽  
2010 ◽  
Vol 06 (02) ◽  
pp. 149-158
Author(s):  
SUHUA WANG ◽  
DEJIAN HUANG
Keyword(s):  
Reactive Oxygen Species ◽  
Quantum Dots ◽  
Organic Dyes ◽  
Resonance Energy Transfer ◽  
Reactive Oxygen ◽  
Resonance Energy ◽  
Oxygen Species ◽  
Positive Side ◽  
Biological Importance ◽  
Organic Sensitizers

In this review, we systematically analyzed the complicated interrelationship between photoluminescent quantum dots (QDs) and reactive oxygen species of biological importance. QDs, when photoexcited, generate reactive oxygen species (ROS), which are partially blamed for the cytotoxicity of QDs. On the positive side, the ability of generating ROS by QDs are exploited in photodynamic therapy using QDs alone or in combination with QD-surface bound organic sensitizers via resonance energy transfer from QDs to the organic dyes. Lastly, depending on the chemical composition and the functionalization of the QDs, ROS are known to quench or switch-on the QD photoluminescence. The selectivity and sensitivity toward specific ROS can be achieved through judicious chemical modification of QD surface coating layers by taking into account the reactivity difference among different ROS. The flexible QD surface functionalization opens up the unprecedented possibility of designer-made nanoprobes for sensing and quantifying ROS of biological importance.

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