scholarly journals Correction to “Intestinal Mucin Induces More Endocytosis but Less Transcytosis of Nanoparticles across Enterocytes by Triggering Nanoclustering and Strengthening the Retrograde Pathway”

2021 ◽  
Author(s):  
Dan Yang ◽  
Dechun Liu ◽  
Mengmeng Qin ◽  
Binlong Chen ◽  
Siyang Song ◽  
...  
Keyword(s):  
Intestinal Mucin

scholarly journals Bacillus thuringiensis Bel Protein Enhances the Toxicity of Cry1Ac Protein to Helicoverpa armigera Larvae by Degrading Insect Intestinal Mucin

2009 ◽  
Vol 75 (16) ◽  
pp. 5237-5243 ◽  
Author(s):  
Shangling Fang ◽  
Li Wang ◽  
Wei Guo ◽  
Xia Zhang ◽  
Donghai Peng ◽  
...  
Keyword(s):  
Bacillus Thuringiensis ◽  
Helicoverpa Armigera ◽  
Trichoplusia Ni ◽  
Knockout Mutant ◽  
Gene Encoding ◽  
In Vitro Degradation ◽  
Intestinal Mucin ◽  
Helicoverpa Armígera ◽  
Cry1ac Protein

ABSTRACT Bacillus thuringiensis has been used as a bioinsecticide to control agricultural insects. Bacillus cereus group genomes were found to have a Bacillus enhancin-like (bel) gene, encoding a peptide with 20 to 30% identity to viral enhancin protein, which can enhance viral infection by degradation of the peritrophic matrix (PM) of the insect midgut. In this study, the bel gene was found to have an activity similar to that of the viral enhancin gene. A bel knockout mutant was constructed by using a plasmid-free B. thuringiensis derivative, BMB171. The 50% lethal concentrations of this mutant plus the cry1Ac insecticidal protein gene were about 5.8-fold higher than those of the BMB171 strain. When purified Bel was mixed with the Cry1Ac protein and fed to Helicoverpa armigera larvae, 3 μg/ml Cry1Ac alone induced 34.2% mortality. Meanwhile, the mortality rate rose to 74.4% when the same amount of Cry1Ac was mixed with 0.8 μg/ml of Bel. Microscopic observation showed a significant disruption detected on the midgut PM of H. armigera larvae after they were fed Bel. In vitro degradation assays showed that Bel digested the intestinal mucin (IIM) of Trichoplusia ni and H. armigera larvae to various degrading products, similar to findings for viral enhancin. These results imply Bel toxicity enhancement depends on the destruction of midgut PM and IIM, similar to the case with viral enhancin. This discovery showed that Bel has the potential to enhance insecticidal activity of B. thuringiensis-based biopesticides and transgenic crops.

Binding of antibiotics to rat intestinal mucin

1986 ◽  
Vol 30 (2-3) ◽  
pp. 181-187 ◽  
Author(s):  
Jun-Ji Niibuchi ◽  
Yukihiko Aramaki ◽  
Seishi Tsuchiya
Keyword(s):  
Intestinal Mucin

scholarly journals The human MUC2 intestinal mucin has cysteine-rich subdomains located both upstream and downstream of its central repetitive region.

1992 ◽  
Vol 267 (30) ◽  
pp. 21375-21383 ◽  
Author(s):  
J.R. Gum ◽  
J.W. Hicks ◽  
N.W. Toribara ◽  
E.M. Rothe ◽  
R.E. Lagace ◽  
...  
Keyword(s):  
Repetitive Region ◽  
Intestinal Mucin

scholarly journals Clinicopathologic and molecular characteristics of gastric cancer showing gastric and intestinal mucin phenotype

2015 ◽  
Vol 106 (8) ◽  
pp. 951-958 ◽  
Author(s):  
Naohide Oue ◽  
Kazuhiro Sentani ◽  
Naoya Sakamoto ◽  
Wataru Yasui
Keyword(s):  
Gastric Cancer ◽  
Molecular Characteristics ◽  
Mucin Phenotype ◽  
Intestinal Mucin

The MUC2 gene product: a human intestinal mucin

1998 ◽  
Vol 30 (7) ◽  
pp. 797-801 ◽  
Author(s):  
Adrian Allen ◽  
David A. Hutton ◽  
Jeffrey P. Pearson
Keyword(s):  
Gene Product ◽  
Intestinal Mucin

Intestinal mucin of germ-free rats. Biochemical and electron-microscopic characterization

1991 ◽  
Vol 222 ◽  
pp. 1-9 ◽  
Author(s):  
Henry S. Slayter ◽  
Jens K. Wold ◽  
Tore Midtvedt
Keyword(s):  
Electron Microscopic ◽  
Germ Free ◽  
Intestinal Mucin

INTERACTION OF EIMERIA TENELLA WITH INTESTINAL MUCIN IN VITRO

2007 ◽  
Vol 93 (3) ◽  
pp. 634-638 ◽  
Author(s):  
J. B. Tierney ◽  
E. Matthews ◽  
S. D. Carrington ◽  
G. Mulcahy
Keyword(s):  
Eimeria Tenella ◽  
Intestinal Mucin

Hydrolyzed Casein Influences Intestinal Mucin Gene Expression in the Rat

2008 ◽  
Vol 56 (14) ◽  
pp. 5572-5576 ◽  
Author(s):  
Kyoung-Sik Han ◽  
Amelie Deglaire ◽  
Ranjita Sengupta ◽  
Paul J. Moughan
Keyword(s):  
Gene Expression ◽  
Mucin Gene ◽  
Intestinal Mucin
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