Reduction-Responsive Polymer Prodrug Micelles with Enhanced Endosomal Escape Capability for Efficient Intracellular Translocation and Drug Release

2019 ◽  
Vol 2 (11) ◽  
pp. 5099-5109 ◽  
Author(s):  
Alhadi Ibrahim ◽  
Etienne Twizeyimana ◽  
Nannan Lu ◽  
Wendong Ke ◽  
Jean Felix Mukerabigwi ◽  
...  
Keyword(s):  
Drug Release ◽  
Endosomal Escape ◽  
Responsive Polymer ◽  
Intracellular Translocation

Thermo-responsive polymer-functionalized mesoporous carbon for controlled drug release

2011 ◽  
Vol 126 (1-2) ◽  
pp. 357-363 ◽  
Author(s):  
Shenmin Zhu ◽  
Chenxin Chen ◽  
Zhixin Chen ◽  
Xinye Liu ◽  
Yao Li ◽  
...  
Keyword(s):  
Drug Release ◽  
Mesoporous Carbon ◽  
Controlled Drug Release ◽  
Responsive Polymer

scholarly journals Characterization and optimization of pH-responsive polymer nanoparticles for drug delivery to oral biofilms

2016 ◽  
Vol 4 (18) ◽  
pp. 3075-3085 ◽  
Author(s):  
Jiayi Zhou ◽  
Benjamin Horev ◽  
Geelsu Hwang ◽  
Marlise I. Klein ◽  
Hyun Koo ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Block Copolymer ◽  
Drug Release ◽  
Polymer Nanoparticles ◽  
Ph Responsive ◽  
Molecular Weights ◽  
Responsive Polymer ◽  
Oral Biofilms ◽  
Block Copolymer Micelles ◽  
Copolymer Micelles

Corona and core molecular weights of p(DMAEMA)-b-p(DMAEMA-co-BMA-co-PAA) block copolymer micelles can be tuned to enhance drug release in response to acidic milieus consistent with oral biofilms.

Responsive polymer–fluorescent carbon nanoparticle hybrid nanogels for optical temperature sensing, near-infrared light-responsive drug release, and tumor cell imaging

Nanoscale ◽  
2014 ◽  
Vol 6 (13) ◽  
pp. 7443-7452 ◽  
Author(s):  
Hui Wang ◽  
Fuyou Ke ◽  
Anton Mararenko ◽  
Zengyan Wei ◽  
Probal Banerjee ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Release ◽  
Tumor Cell ◽  
Near Infrared ◽  
Cell Imaging ◽  
Temperature Sensing ◽  
Infrared Light ◽  
Near Infrared Light ◽  
Carbon Nanoparticle ◽  
Responsive Polymer

The paper demonstrates the synthesis of carbon-based responsive hybrid nanogels and their applications including sensing, cell imaging and drug delivery.

A charge-conversional intracellular-activated polymeric prodrug for tumor therapy

2016 ◽  
Vol 7 (12) ◽  
pp. 2253-2263 ◽  
Author(s):  
Yue Wang ◽  
Shixian Lv ◽  
Mingxiao Deng ◽  
Zhaohui Tang ◽  
Xuesi Chen
Keyword(s):  
Drug Release ◽  
Tumor Therapy ◽  
Circulation Time ◽  
Cellular Internalization ◽  
Dual Responsive ◽  
Polymeric Prodrug ◽  
Responsive Polymer ◽  
A Charge

A pH and redox dual responsive polymer–PTX conjugate with a prolonged circulation time, enhanced cellular internalization and timely intracellular drug release, is reported.

Synthesis of thermal and oxidation dual responsive polymers for reactive oxygen species (ROS)-triggered drug release

2015 ◽  
Vol 6 (5) ◽  
pp. 738-747 ◽  
Author(s):  
Chunsheng Xiao ◽  
Jianxun Ding ◽  
Lili Ma ◽  
Chenguang Yang ◽  
Xiuli Zhuang ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Drug Release ◽  
Main Chain ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Responsive Polymers ◽  
Dual Responsive ◽  
Responsive Polymer ◽  
Triggered Drug Release

A PEG-based main chain thermo-responsive polymer with oxidation-triggerable thioether groups: synthesis, characterization and its use for ROS-responsive drug release.

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