Space-Oriented Nanofibrous Scaffold with Silicon-Doped Amorphous Calcium Phosphate Nanocoating for Diabetic Wound Healing

2019 ◽  
Vol 2 (2) ◽  
pp. 787-795 ◽  
Author(s):  
Yuqi Jiang ◽  
Yiming Han ◽  
Jie Wang ◽  
Fang Lv ◽  
Zhengfang Yi ◽  
...  
Author(s):  
Tingting Huang ◽  
Bolei Yuan ◽  
Wei Jiang ◽  
Yi Ding ◽  
Lin Jiang ◽  
...  

The hyperglycemic environment and the presence of bacterial infections delay the healing of diabetic wounds. Herein, glucose oxidase (GOx) and Fe3O4/TiO2/Ag3PO4 was embedded in a polyacrylic acid-calcium phosphate (PAA-CaPs@Nps@GOx) hydrogel...


2021 ◽  
Author(s):  
Amritha Vijayan ◽  
Nanditha C. K. ◽  
G. S. Vinod Kumar

Nanofibrous scaffold enriched with dual growth factor nanoparticles for diabetic wound healing.


Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
CBS Lau ◽  
VKM Lau ◽  
CL Liu ◽  
PKK Lai ◽  
JCW Tam ◽  
...  

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 634-P
Author(s):  
PIUL S. RABBANI ◽  
JOSHUA A. DAVID ◽  
DARREN L. SULTAN ◽  
ALVARO P. VILLARREAL-PONCE ◽  
JENNIFER KWONG ◽  
...  

Nanomedicine ◽  
2020 ◽  
Vol 15 (23) ◽  
pp. 2241-2253
Author(s):  
Pengju Zhang ◽  
Yuqi Jiang ◽  
Dan Liu ◽  
Yan Liu ◽  
Qinfei Ke ◽  
...  

Aim: To develop an effective strategy for increasing angiogenesis at diabetic wound sites and thereby accelerating wound healing. Materials & methods: A micropatterned nanofibrous scaffold with bioglass nanoparticles encapsulated inside coaxial fibers was prepared by electrospinning. Results: Si ions could be released in a sustained manner from the scaffolds. The hierarchical micro-/nano-structure of the scaffold was found to act as a temporary extracellular matrix to promote endothelial cell adhesion and growth. The scaffold greatly improved angiogenesis and collagen deposition at the wound site, which shortened the healing period of diabetic wounds. Conclusion: This study provides a promising therapeutic option for chronic diabetic wounds with improved angiogenesis.


2019 ◽  
Vol 8 (12) ◽  
pp. 1801210 ◽  
Author(s):  
Maggie J. Malone‐Povolny ◽  
Sara E. Maloney ◽  
Mark H. Schoenfisch

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