Super Mechanical Stimuli Responsive Hydrogel: Dynamic Cues for Cell Applications

2018 ◽  
Vol 2 (1) ◽  
pp. 277-283 ◽  
Author(s):  
Ravichandran H. Kollarigowda ◽  
Anu Stella Mathews ◽  
Sinoj Abraham
2016 ◽  
Vol 4 (37) ◽  
pp. 8724-8730 ◽  
Author(s):  
Xianchao Du ◽  
Fan Xu ◽  
Mao-Sen Yuan ◽  
Pengchong Xue ◽  
Lei Zhao ◽  
...  

A fluorenone-based stimuli-responsive solid luminescence color switching molecule was successfully constructed.


Author(s):  
Shohei Simizu ◽  
Shakkeeb Thazhathethil ◽  
Kiyonori Takahashi ◽  
Takayoshi Nakamura ◽  
Yoshimitsu Sagara

Cyclophanes featuring luminophores are considered promising candidates as thermal or mechanical stimuli-responsive luminescent materials. The mechanism of the changes in the photophysical properties on the crystal-crystal or crystal-amorphous phase transitions...


2016 ◽  
Vol 4 (24) ◽  
pp. 4278-4286 ◽  
Author(s):  
Raja Rajamanickam ◽  
Siyeon Baek ◽  
Kihak Gwon ◽  
Youngmin Hwang ◽  
Kwanwoo Shin ◽  
...  

Hybrid hollow capsules crosslinked at freezing temperatures that recover elastically after large, repetitive deformations as mechanical stimuli-responsive drug delivery vehicles.


2012 ◽  
Vol 11 (9) ◽  
pp. 1414 ◽  
Author(s):  
Yujian Zhang ◽  
Jingwei Sun ◽  
Gaofeng Bian ◽  
Yiyi Chen ◽  
Mi Ouyang ◽  
...  

Author(s):  
Wen-lung Wu

The mantle of bivalves has come entirely to enclose the laterally compressed body and the mantle margin has assumed a variety of functions, one of the pricipal ones being sensory. Ciliary tufts, which are probably sensory, have been reported from the mantle and siphons of several bivalves1∽4. Certain regions of the mantle margin are likely to be more or less, sensitive to certain stimuli than others. The inhalant siphon is likely to be particularly sensitive to both chemical and mechanical stimuli, whereas the exhalant siphon will be less sensitive to both. The distribution and density of putative sensory receptors on the in-and ex-halant siphon is compared in this paper.The excised siphons were fixed in glutaraldehyde and osmium tetroxide, the whole procedure of SEM study is recorded in Wu's thesis.Type II cilia cover the tips of tentacles, 6.13um. Type IV and type V cilia are found on the surface of tentacles. Type IV cilia are occasionally present at the tips of tentacles, 8 um long. They are the commonest type on the surface of tentacles. Type VI cilia occor in the internal surface of the inhalant siphon, but are not found on the surface of tentacles, 6.7-10um long.


2020 ◽  
Vol 11 (24) ◽  
pp. 3940-3950 ◽  
Author(s):  
Patrick Verkoyen ◽  
Holger Frey

Amino-functional polyethers have emerged as a new class of “smart”, i.e. pH- and thermoresponsive materials. This review article summarizes the synthesis and applications of these materials, obtained from ring-opening of suitable epoxide monomers.


2020 ◽  
Vol 134 (17) ◽  
pp. 2399-2418
Author(s):  
Yoshito Yamashiro ◽  
Hiromi Yanagisawa

Abstract Blood vessels are constantly exposed to mechanical stimuli such as shear stress due to flow and pulsatile stretch. The extracellular matrix maintains the structural integrity of the vessel wall and coordinates with a dynamic mechanical environment to provide cues to initiate intracellular signaling pathway(s), thereby changing cellular behaviors and functions. However, the precise role of matrix–cell interactions involved in mechanotransduction during vascular homeostasis and disease development remains to be fully determined. In this review, we introduce hemodynamics forces in blood vessels and the initial sensors of mechanical stimuli, including cell–cell junctional molecules, G-protein-coupled receptors (GPCRs), multiple ion channels, and a variety of small GTPases. We then highlight the molecular mechanotransduction events in the vessel wall triggered by laminar shear stress (LSS) and disturbed shear stress (DSS) on vascular endothelial cells (ECs), and cyclic stretch in ECs and vascular smooth muscle cells (SMCs)—both of which activate several key transcription factors. Finally, we provide a recent overview of matrix–cell interactions and mechanotransduction centered on fibronectin in ECs and thrombospondin-1 in SMCs. The results of this review suggest that abnormal mechanical cues or altered responses to mechanical stimuli in EC and SMCs serve as the molecular basis of vascular diseases such as atherosclerosis, hypertension and aortic aneurysms. Collecting evidence and advancing knowledge on the mechanotransduction in the vessel wall can lead to a new direction of therapeutic interventions for vascular diseases.


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