Acid Susceptible Ultrathin Mesoporous Silica Coated on Layered Double Hydroxide Nanoplates for pH Responsive Cancer Therapy

2018 ◽  
Vol 1 (3) ◽  
pp. 928-935 ◽  
Author(s):  
Wen Cao ◽  
Faheem Muhammad ◽  
Yuan Cheng ◽  
Min Zhou ◽  
Qian Wang ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Mesoporous Silica ◽  
Layered Double Hydroxide ◽  
Ph Responsive ◽  
Double Hydroxide

Facile synthesis of pH-responsive doxorubicin-loaded layered double hydroxide for efficient cancer therapy

2018 ◽  
Vol 6 (36) ◽  
pp. 5768-5774 ◽  
Author(s):  
Abdul Hakeem ◽  
Guiting Zhan ◽  
Qingbo Xu ◽  
Tuying Yong ◽  
Xiangliang Yang ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Layered Double Hydroxide ◽  
Positive Charge ◽  
Ph Responsive ◽  
Facile Synthesis ◽  
Anticancer Efficacy ◽  
Double Hydroxide

A method to load doxorubicin with positive charge into layered double hydroxide has been developed to improve its anticancer efficacy.

scholarly journals A pH-responsive ultrathin Cu-based nanoplatform for specific photothermal and chemodynamic synergistic therapy

2021 ◽  
Vol 12 (7) ◽  
pp. 2594-2603
Author(s):  
Tingting Hu ◽  
Liang Yan ◽  
Zhengdi Wang ◽  
Weicheng Shen ◽  
Ruizheng Liang ◽  
...  
Keyword(s):  
Glucose Oxidase ◽  
Layered Double Hydroxide ◽  
Ph Responsive ◽  
Double Hydroxide

A pH-responsive multifunctional nanosystem was synthesized by loading glucose oxidase (GOD) onto CuFe-layered double hydroxide (LDH) nanosheets, which exhibited synchronous acid-enhanced/responsive photothermal and chemodynamic synergistic therapy.

scholarly journals Synthesis of surface capped mesoporous silica nanoparticles for pH-stimuli responsive drug delivery applications

MedChemComm ◽  
2017 ◽  
Vol 8 (9) ◽  
pp. 1797-1805 ◽  
Author(s):  
Madhappan Santha Moorthy ◽  
Subramanian Bharathiraja ◽  
Panchanathan Manivasagan ◽  
Kang Dae Lee ◽  
Junghwan Oh
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Drug Carrier ◽  
Stimuli Responsive ◽  
Ph Responsive ◽  
Drug Delivery Applications

Herein, we propose a “host–guest” complexation-based mesoporous silica drug carrier, MSNs@Mela@TTM, for pH-responsive drug delivery applications in cancer therapy.

A pH-responsive dissociable mesoporous silica-based nanoplatform enabling efficient dual-drug co-delivery and rapid clearance for cancer therapy

2020 ◽  
Vol 8 (12) ◽  
pp. 3418-3429 ◽  
Author(s):  
Yongju He ◽  
Linjie Shao ◽  
Ibrahim Usman ◽  
Yao Hu ◽  
Anqiang Pan ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Mesoporous Silica ◽  
Ph Responsive ◽  
Epr Effect ◽  
Large Size ◽  
Rapid Clearance ◽  
Tumor Accumulation ◽  
Dual Drug

A pH-responsive dissociable mesoporous silica-based cluster with efficient dual-drug co-delivery for combinational cancer therapy, tumor accumulation via its large size-favored EPR effect and rapid clearance by its acid-triggered dissociation.

scholarly journals Layered double hydroxide nanostructures and nanocomposites for biomedical applications

2019 ◽  
Vol 7 (37) ◽  
pp. 5583-5601 ◽  
Author(s):  
Li Yan ◽  
Sevil Gonca ◽  
Guangyu Zhu ◽  
Wenjun Zhang ◽  
Xianfeng Chen
Keyword(s):  
Cancer Therapy ◽  
Layered Double Hydroxide ◽  
Biomedical Applications ◽  
Antibacterial Treatment ◽  
Significant Interest ◽  
Double Hydroxide

Layered double hydroxide (LDH) nanostructures and related nanocomposites have attracted significant interest in biomedical applications including cancer therapy, bioimaging and antibacterial treatment.

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