Mesoporous Silica Nanoprodrug Encapsulated with Near-Infrared Absorption Dye for Photothermal Therapy Combined with Chemotherapy

Author(s):  
Shiyuan Peng ◽  
Fusheng Zhang ◽  
Baihao Huang ◽  
Jufang Wang ◽  
Lijuan Zhang
2018 ◽  
Vol 6 (47) ◽  
pp. 7877-7888 ◽  
Author(s):  
Xuexin Bi ◽  
Huiling Su ◽  
Wei Shi ◽  
Xin Liu ◽  
Zi He ◽  
...  

Homogenous poly(pyrrole-3-carboxylic acid) nanoparticles with high near-infrared absorption and abundant functional groups were fabricated using a facile reverse microemulsion method.


Biomaterials ◽  
2013 ◽  
Vol 34 (12) ◽  
pp. 3150-3158 ◽  
Author(s):  
Shun Shen ◽  
Hongyan Tang ◽  
Xiaotong Zhang ◽  
Jinfeng Ren ◽  
Zhiqing Pang ◽  
...  

2019 ◽  
Vol 48 (10) ◽  
pp. 3360-3368 ◽  
Author(s):  
Qing Cao ◽  
Xin Guo ◽  
Wenlong Zhang ◽  
Guoqiang Guan ◽  
Xiaojuan Huang ◽  
...  

Hydrophilic flower-like Fe7S8/Bi2S3 superstructures with improved near-infrared absorption and photostability for good chemo-photothermal synergistic therapeutic effect.


2015 ◽  
Vol 3 (46) ◽  
pp. 8939-8948 ◽  
Author(s):  
Min Zhou ◽  
Shaoli Song ◽  
Jun Zhao ◽  
Mei Tian ◽  
Chun Li

Targeted FA–CuS NPs can significantly improve the tumor uptake; the integration of 64Cu into NPs with strong near-infrared absorption makes them suitable for PET imaging, and image-guided photothermal therapy; targeted FA–CuS NPs mediate a substantially greater therapeutic effect compared with photothermal therapy with non-targeted CuS NPs.


RSC Advances ◽  
2017 ◽  
Vol 7 (17) ◽  
pp. 10143-10149 ◽  
Author(s):  
Ruiyang Zhao ◽  
Xiaoxia Sun ◽  
Jing Sun ◽  
Lei Wang ◽  
Jishu Han

PPy-Modified CuS nanoprisms with intense near-infrared absorption, excellent biocompatibility and photothermal conversion performance, were applied to in vivo photothermal therapy.


2017 ◽  
Vol 5 (44) ◽  
pp. 8833-8838 ◽  
Author(s):  
Lin Fang ◽  
Weiqi Wang ◽  
Yang Liu ◽  
Zhigang Xie ◽  
Li Chen

Mesoporous silica was partly coated on AuNRs (Janus AuNRs@mSiO2) as a hyperthermia and drug delivery platform for chemo–photothermal therapy.


2021 ◽  
Vol 21 (9) ◽  
pp. 4553-4564
Author(s):  
Yihan Kong ◽  
Xue Li ◽  
Xiaojing Liu ◽  
Jingjing Pang ◽  
Xinling Mu ◽  
...  

The use of chemotherapy combined with photothermal therapy (PTT) is getting a focus topic for cancer treatment. Duing this research, the double targeting drug delivery system of nedaplatin (NDP)–carboxyl-functionalized magnetic mesoporous silica (MMSN-COOH)–galactosylated chitosan (GC) nanoparticles (NPs) was constructed. Because MMSNs have special physical properties, it can target to the specific area. In addition, it’s able to convert absorbed near-infrared (NIR) light into heat energy for photothermal therapy (PTT). Furthermore, the thermal energy generated by MMSNs under NIR lasers can accelerate the release of drug from preparations. Moreover, GC modified MMSNs-COOH as a carrier can increase the drug uptake of cancer cells that highly express galectins in vitro, resulting in cancer cell apoptosis, and thus increasing the targeting of cancerous tissue in vivo. The experimental consequences in vitro and in vivo revealed that the NDP@MMSNCOOH-GC NPs combined with PTT could avoid systemic toxicity and improve biosecurity while having good anticancer effect.


2017 ◽  
Vol 5 (27) ◽  
pp. 5479-5487 ◽  
Author(s):  
Yue Cao ◽  
Yannan Wu ◽  
Guannan Wang ◽  
Jingwen Yi ◽  
Chunlei Yu ◽  
...  

Conjugated polymers with intensive near-infrared absorption and high photothermal conversion efficiency have emerged as a new generation of photothermal therapy and photoacoustic imaging agents for cancer therapy.


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