1,2,4-Triaminobenzene as a Fluorescent Probe for Intracellular pH Imaging and Point-of-Care Ammonia Sensing

2021 ◽  
Author(s):  
Shuangting Yang ◽  
Yuanjin Zhan ◽  
Wen Shou ◽  
Lifen Chen ◽  
Zhenyu Lin ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Intracellular Ph ◽  
Point Of Care ◽  
Ammonia Sensing ◽  
Ph Imaging

Construction of Polysiloxane-Based Fluorescent Probe for Visualizing The pH Down-regulation

2021 ◽  
Author(s):  
Xiaoni Wang ◽  
Zhiming Gou ◽  
Minggang Tian ◽  
Yujing Zuo
Keyword(s):  
Fluorescent Probe ◽  
Intracellular Ph ◽  
Cell Apoptosis ◽  
Pathological Process ◽  
Down Regulation ◽  
Ph Values

Intracellular pH values change is a significant physiological and pathological process and plays vital roles in autophagy, self-repairing, and programmed cell apoptosis. A unique fluorescent probe (PN-1) based on polysiloxanes...

Light-activated “cycle-reversible intramolecular charge transfer” fluorescent probe: monitoring of pHi trace change induced by UV light in programmed cell death

2019 ◽  
Vol 55 (36) ◽  
pp. 5279-5282 ◽  
Author(s):  
Tao Jiang ◽  
Xin Wang ◽  
Ge Wang ◽  
Yafu Wang ◽  
Kui Wang ◽  
...  
Keyword(s):  
Cell Death ◽  
Charge Transfer ◽  
Programmed Cell Death ◽  
Synergistic Effect ◽  
Fluorescent Probe ◽  
Intracellular Ph ◽  
Intramolecular Charge Transfer ◽  
Uv Light

A light-activated fluorescent probe shows cycle-reversible intramolecular charge transfer for different intracellular pH under the synergistic effect of protonation–deprotonation.

scholarly journals A Near-Infrared Fluorescent Probe Based on a FRET Rhodamine Donor Linked to a Cyanine Acceptor for Sensitive Detection of Intracellular pH Alternations

Molecules ◽  
2018 ◽  
Vol 23 (10) ◽  
pp. 2679 ◽  
Author(s):  
Yibin Zhang ◽  
Jianheng Bi ◽  
Shuai Xia ◽  
Wafa Mazi ◽  
Shulin Wan ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Intracellular Ph ◽  
Near Infrared ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
Sensitive Detection ◽  
Solution Ph ◽  
Acidic Conditions ◽  
Ph Level ◽  
Rhodamine Dye

A fluorescence resonance energy transfer (FRET)-based near-infrared fluorescent probe (B+) for double-checked sensitive detection of intracellular pH changes has been synthesized by binding a near-infrared rhodamine donor to a near-infrared cyanine acceptor through robust C-N bonds via a nucleophilic substitution reaction. To demonstrate the double-checked advantages of probe B+, a near-infrared probe (A) was also prepared by modification of a near-infrared rhodamine dye with ethylenediamine to produce a closed spirolactam residue. Under basic conditions, probe B+ shows only weak fluorescence from the cyanine acceptor while probe A displays nonfluorescence due to retention of the closed spirolactam form of the rhodamine moiety. Upon decrease in solution pH level, probe B+ exhibits a gradual fluorescence increase from rhodamine and cyanine constituents at 623 nm and 743 nm respectively, whereas probe A displays fluorescence increase at 623 nm on the rhodamine moiety as acidic conditions leads to the rupture of the probe spirolactam rings. Probes A and B+ have successfully been used to monitor intracellular pH alternations and possess pKa values of 5.15 and 7.80, respectively.

Reversible Self-Assembly of Nanoprobes in Live Cells for Dynamic Intracellular pH Imaging

ACS Nano ◽  
2019 ◽  
Author(s):  
Bo Dong ◽  
Shuangli Du ◽  
Chunxiao Wang ◽  
Haohao Fu ◽  
Qiang Li ◽  
...  
Keyword(s):  
Intracellular Ph ◽  
Self Assembly ◽  
Live Cells ◽  
Ph Imaging

Design and validation of a new ratiometric intracellular pH imaging probe using lanthanide-doped upconverting nanoparticles

2017 ◽  
Vol 46 (40) ◽  
pp. 13957-13965 ◽  
Author(s):  
Shuoren Du ◽  
Javier Hernández-Gil ◽  
Hao Dong ◽  
Xiaoyu Zheng ◽  
Guangming Lyu ◽  
...  
Keyword(s):  
Intracellular Ph ◽  
Quantitative Imaging ◽  
Living Cells ◽  
Ph Sensitive ◽  
Upconversion Nanoparticles ◽  
Imaging Probe ◽  
Ph Imaging ◽  
Ratiometric Probe ◽  
Subcellular Level

A ratiometric probe based on upconversion nanoparticles modified with a pH sensitive moiety for the quantitative imaging of pH at the subcellular level in living cells.

‘Off–on’ switchable fluorescent probe for prompt and cost-efficient detection of bacteria

2019 ◽  
Vol 43 (33) ◽  
pp. 13094-13102
Author(s):  
Giorgia Giovannini ◽  
Vladimir Gubala ◽  
Andrew J. Hall
Keyword(s):  
Fluorescent Probe ◽  
Bacterial Infections ◽  
Point Of Care ◽  
Lab On A Chip ◽  
Human Samples ◽  
Efficient Detection ◽  
Prevention And Treatment ◽  
Cost Efficient

The rapid and straightforward detection of bacteria in food and human samples is becoming important, particularly in view of the development of point-of-care devices and lab-on-a-chip tools for prevention and treatment of bacterial infections.

A dual functional fluorogenic probe for visualization of intracellular pH and formaldehyde with distinct fluorescence signals

2018 ◽  
Vol 16 (25) ◽  
pp. 4628-4632 ◽  
Author(s):  
Zhenda Xie ◽  
Biao Yin ◽  
Jiajie Shen ◽  
Danqi Hong ◽  
Liquan Zhu ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Intracellular Ph ◽  
Dual Functional ◽  
Fluorogenic Probe

We present a dual functional fluorescent probe (DPFP) for imaging pH and formaldehyde (FA) with distinct fluorescence signals.

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