Directional Propulsion of DNA Microspheres Based on Light-Induced Asymmetric Growth of Peptide Nanofibers

2021 ◽  
Author(s):  
Hiroshi Inaba ◽  
Kenji Hatta ◽  
Kazunori Matsuura
Keyword(s):  
Peptide Nanofibers ◽  
Asymmetric Growth ◽  
Dna Microspheres

scholarly journals Injectable nanofibrillar hydrogels based on charge-complementary peptide co-assemblies

2021 ◽  
Author(s):  
Bethsymarie Soto Morales ◽  
Renjie Liu ◽  
Juanpablo Olguin ◽  
Abigail M Ziegler ◽  
Stephanie M Herrera ◽  
...  
Keyword(s):  
Minimally Invasive ◽  
Injectable Hydrogels ◽  
Therapeutic Delivery ◽  
Peptide Nanofibers

Injectable hydrogels are attractive for therapeutic delivery because they can be locally administered through minimally-invasive routes. Charge-complementary peptide nanofibers provide hydrogels that are suitable for encapsulation of biotherapeutics, such as...

scholarly journals Neonatal brain abscess development following fetal scalp electrode placement: a rare complication

2021 ◽  
Author(s):  
T. Fick ◽  
P. A. Woerdeman
Keyword(s):  
Brain Abscess ◽  
Electrode Placement ◽  
Superficial Infection ◽  
Skin Site ◽  
Scalp Electrode ◽  
Large Brain ◽  
Fetal Scalp ◽  
Asymmetric Growth ◽  
Clinical Illness

AbstractA fetal scalp electrode (FSE) is a frequently used investigation during labor. However, it is an invasive procedure which can lead to complications. Our patient developed a very large brain abscess after initial superficial infection of the skin site due to an FSE. The patient was admitted to the hospital after an asymmetric growth of the skull was noticed with no further signs of clinical illness. MRI showed a very large brain abscess which was aspirated and treated with antibiotics for 10 weeks. A 2-year follow-up showed only a slight developmental delay in gross motor skills. Only once before a similar case has been described at which the patient developed a brain abscess after superficial infection of the scalp following an FSE. In both cases, the brain abscess was noticed due to an asymmetric growth of the skull without any further signs of clinical illness. A brain abscess has a high mortality and morbidity rate, and early diagnosis is vital for the optimal outcome. We therefore recommend to organize an out-patient clinical follow-up for every infant with a superficial infection of the skin site after placement of an FSE.

Self-assembled IKVAV peptide nanofibers promote adherence of PC12 cells

2006 ◽  
Vol 26 (5) ◽  
pp. 594-596 ◽  
Author(s):  
Yongchao Wu ◽  
Qixin Zheng ◽  
Jingyuan Du ◽  
Yulin Song ◽  
Bin Wu ◽  
...  
Keyword(s):  
Pc12 Cells ◽  
Peptide Nanofibers ◽  
Self Assembled

Abstract 17071: Growth Asymmetry, Head Circumference and Neurodevelopmental Outcomes in Infants with Single Ventricles

Circulation ◽  
2014 ◽  
Vol 130 (suppl_2) ◽  
Author(s):  
Thomas A Miller ◽  
Victor Zak ◽  
Peter Shrader ◽  
Chitra Ravishankar ◽  
Victoria L Pemberton ◽  
...  
Keyword(s):  
Gestational Age ◽  
Head Circumference ◽  
Single Ventricle ◽  
Univariate Analysis ◽  
Somatic Growth ◽  
Z Score ◽  
Neurodevelopmental Outcomes ◽  
Head Growth ◽  
Developmental Index ◽  
Asymmetric Growth

Poor somatic growth is common in infants with single ventricle (SV) physiology and has been linked to increased morbidity and impaired neurodevelopment. Asymmetry in somatic growth, a potential brain-sparing adaptation, is important in predicting outcomes in premature and small for gestational age (SGA) infants. Objectives: To assess variability in growth asymmetry and its associations with neurodevelopment in infants with SV. Methods: We analyzed growth asymmetry (weight for age z-score (WAZ) minus head circumference for age z-score (HCAZ)), relative head growth (change in cm/change in kg), HCAZ, and change in HCAZ from baseline to pre-Glenn in subjects prospectively enrolled in the Pediatric Heart Network Infant Single Ventricle (ISV) trial. Associations between these indices and results of the Psychomotor Developmental Index (PDI) and Mental Developmental Index (MDI) of the Bayley Scales of Infant Development-II (BSID) at 14 months were assessed. Results: Of the 230 patients enrolled in ISV, complete biometric data and BSID results were available in 168 (73%). For this cohort, age at enrollment was 21±9 days, age at pre-Glenn was 167±52 days, gestational age was 38.3±1.4 weeks, and 71% were male. Growth asymmetry varied across the cohort at enrollment (0.43 ±1.02, range -2.85 to 4.84) and the pre-Glenn visit (-0.23 ±1.21, range -4.45 to 3.00) as did the relative head growth (2.40±0.86, range 0.50 to 8.00). BSID scores were not associated with indices of growth asymmetry. In univariate analysis, larger pre-Glenn HCAZ correlated with higher MDI (r=0.21, p=0.006) and PDI (r=0.38, p<0.001) and greater increase in HCAZ from enrollment to pre-Glenn was associated with higher PDI (r=0.15, p=0.049). In multivariable modeling adjusting for site, serious adverse events, stage 1 length of stay, and height at 14 months, pre-Glenn HCAZ was an independent predictor of PDI (p=0.03), but not MDI. For each one unit Z-score increase in pre-Glenn HCAZ, the predicted PDI score increased by 2.5 points. Conclusions: In infants with SV, BSID scores were associated with pre-Glenn HCAZ but not with the degree of asymmetric growth. Future studies should explore why asymmetric growth that seems important in premature and SGA infants appears less relevant in infants with SV.

scholarly journals Characterization of the asymmetric growth of gravistimulated snapdragon spikes by stem and cell dimension analyses

2003 ◽  
Vol 90 (6) ◽  
pp. 849-856 ◽  
Author(s):  
H. Friedman ◽  
S. Meir ◽  
A. H. Halevy ◽  
S. Philosoph-Hadas
Keyword(s):  
Cell Dimension ◽  
Asymmetric Growth

Relief of Asymmetric Growth Stresses in Logs

Holzforschung ◽  
1978 ◽  
Vol 32 (4) ◽  
pp. 123-127
Author(s):  
Chiruvai P. Vendhan ◽  
Robert R. Archer
Keyword(s):  
Growth Stresses ◽  
Asymmetric Growth

Tuning carbohydrate density enhances protein binding and inhibition by glycosylated β-sheet peptide nanofibers

2018 ◽  
Vol 6 (9) ◽  
pp. 2327-2335 ◽  
Author(s):  
Antonietta Restuccia ◽  
Gregory A. Hudalla
Keyword(s):  
Protein Binding ◽  
Binding Affinity ◽  
Binding Proteins ◽  
Carbohydrate Binding ◽  
Peptide Nanofibers ◽  
Carbohydrate Binding Proteins ◽  
Β Sheet

The efficacy of glycosylated β-sheet peptide nanofibers for inhibiting carbohydrate-binding proteins can be increased by tuning carbohydrate density to maximize protein binding affinity.

scholarly journals Functional Peptide Nanofibers with Unique Tumor Targeting and Enzyme-Induced Local Retention Properties

2018 ◽  
Vol 28 (44) ◽  
pp. 1803969 ◽  
Author(s):  
Vanessa Bellat ◽  
Richard Ting ◽  
Teresa L. Southard ◽  
Linda Vahdat ◽  
Henrik Molina ◽  
...  
Keyword(s):  
Tumor Targeting ◽  
Peptide Nanofibers ◽  
Functional Peptide
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