scholarly journals Injectable nanofibrillar hydrogels based on charge-complementary peptide co-assemblies

2021 ◽  
Author(s):  
Bethsymarie Soto Morales ◽  
Renjie Liu ◽  
Juanpablo Olguin ◽  
Abigail M Ziegler ◽  
Stephanie M Herrera ◽  
...  
Keyword(s):  
Minimally Invasive ◽  
Injectable Hydrogels ◽  
Therapeutic Delivery ◽  
Peptide Nanofibers

Injectable hydrogels are attractive for therapeutic delivery because they can be locally administered through minimally-invasive routes. Charge-complementary peptide nanofibers provide hydrogels that are suitable for encapsulation of biotherapeutics, such as...

SHAPE RETAINING INJECTABLE HYDROGELS FOR MINIMALLY INVASIVE BULKING

2004 ◽  
Vol 172 (2) ◽  
pp. 763-768 ◽  
Author(s):  
AMANDA J. THORNTON ◽  
EBEN ALSBERG ◽  
ELLIOT E. HILL ◽  
DAVID J. MOONEY
Keyword(s):  
Minimally Invasive ◽  
Injectable Hydrogels

Facile Engineering of ECM-Mimetic Injectable Dual Crosslinking Hydrogels with Excellent Mechanical Resilience, Tissue Adhesion, and Biocompatibility

2021 ◽  
Author(s):  
Han Fu ◽  
Chenggong Yu ◽  
Xiaodi Li ◽  
Hongying Bao ◽  
Bo Zhang ◽  
...  
Keyword(s):  
Minimally Invasive ◽  
Minimally Invasive Procedures ◽  
Invasive Procedures ◽  
Injectable Hydrogels ◽  
Tissue Adhesion

Injectable hydrogels have attracted ever-increasing interests for their cell/biomaterials delivery ability through minimally invasive procedures. Nevertheless, it is still a challenge to simply fabricate natural biopolymers-based injectable hydrogels possessing satisfactory...

Design of Nanocomposite Injectable Hydrogels for Minimally Invasive Surgery

2019 ◽  
Vol 52 (8) ◽  
pp. 2101-2112 ◽  
Author(s):  
Etienne Piantanida ◽  
Giuseppe Alonci ◽  
Alessandro Bertucci ◽  
Luisa De Cola
Keyword(s):  
Minimally Invasive Surgery ◽  
Minimally Invasive ◽  
Invasive Surgery ◽  
Injectable Hydrogels

Minimally invasive mandibular bone augmentation using injectable hydrogels

2012 ◽  
Vol 6 (S3) ◽  
pp. s15-s23 ◽  
Author(s):  
Elena Martínez-Sanz ◽  
Oommen P. Varghese ◽  
Marta Kisiel ◽  
Thomas Engstrand ◽  
Karoline M. Reich ◽  
...  
Keyword(s):  
Minimally Invasive ◽  
Bone Augmentation ◽  
Injectable Hydrogels ◽  
Mandibular Bone

A smart injectable composite hydrogel with magnetic navigation and controlled glutathione release for promoting in-situ chondrocyte array and self-healing in damaged cartilage tissue

2021 ◽  
Author(s):  
Min-Yu Chiang ◽  
I-Yun Cheng ◽  
Syun-Hong Chou ◽  
Jen-Hao Tsai ◽  
Yong-Ji Chen ◽  
...  
Keyword(s):  
Articular Cartilage ◽  
Minimally Invasive ◽  
Cartilage Tissue ◽  
Self Healing ◽  
Magnetic Navigation ◽  
Surgical Operation ◽  
Injectable Hydrogels ◽  
Cartilage Lesions ◽  
Articular Cartilage Lesions

Injectable cell-based hydrogels allow surgical operation in a minimally invasive way for articular cartilage lesions but the chondrocytes in the injectable hydrogels are difficultly arrayed and fixed at the site...

Advanced Material Catheter (AMCath), a minimally invasive endocardial catheter for the delivery of fast-gelling covalently cross-linked hyaluronic acid hydrogels

2018 ◽  
Vol 33 (5) ◽  
pp. 681-692 ◽  
Author(s):  
Eimear B Dolan ◽  
Lenka Kovarova ◽  
Hugh O'Neill ◽  
Martin Pravda ◽  
Romana Sulakova ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Left Ventricle ◽  
Minimally Invasive ◽  
Viscoelastic Properties ◽  
Advanced Materials ◽  
Regenerative Therapy ◽  
Injectable Hydrogels ◽  
Adipose Derived Stem Cell

Injectable hydrogels that aim to mechanically stabilise the weakened left ventricle wall to restore cardiac function or to deliver stem cells in cardiac regenerative therapy have shown promising data. However, the clinical translation of hydrogel-based therapies has been limited due to difficulties injecting them through catheters. We have engineered a novel catheter, Advanced Materials Catheter (AMCath), that overcomes translational hurdles associated with delivering fast-gelling covalently cross-linked hyaluronic acid hydrogels to the myocardium. We developed an experimental technique to measure the force required to inject such hydrogels and determined the mechanical/viscoelastic properties of the resulting hydrogels. The preliminary in vivo feasibility of delivering fast-gelling hydrogels through AMCath was demonstrated by accessing the porcine left ventricle and showing that the hydrogel was retained in the myocardium post-injection (three 200 μL injections delivered, 192, 204 and 183 μL measured). However, the mechanical properties of the hydrogels were reduced by passage through AMCath (≤20.62% reduction). We have also shown AMCath can be used to deliver cardiopoietic adipose-derived stem cell-loaded hydrogels without compromising the viability (80% viability) of the cells in vitro. Therefore, we show that hydrogel/catheter compatibility issues can be overcome as we have demonstrated the minimally invasive delivery of a fast-gelling covalently cross-linked hydrogel to the beating myocardium.

Considerations in Dysphagia Management Following Esophagectomy

2016 ◽  
Vol 1 (13) ◽  
pp. 169-176
Author(s):  
Lisa M. Evangelista ◽  
James L. Coyle
Keyword(s):  
Esophageal Cancer ◽  
Minimally Invasive ◽  
Minimally Invasive Surgical Procedures ◽  
Esophageal Resection ◽  
Minimally Invasive Surgical ◽  
Operative Complications ◽  
Swallowing Difficulties ◽  
Epidemiological Impact ◽  
Invasive Techniques ◽  
Management Of Dysphagia

Esophageal cancer is the sixth leading cause of death from cancer worldwide. Esophageal resection is the mainstay treatment for cancers of the esophagus. While curative, surgical resection may result in swallowing difficulties that require intervention from speech-language pathologists (SLPs). Minimally invasive surgical procedures for esophageal resection have aimed to reduce morbidity and mortality associated with more invasive techniques. Both intra-operative and post-operative complications, regardless of the surgical approach, can result in dysphagia. This article will review the epidemiological impact of esophageal cancers, operative complications resulting in dysphagia, and clinical assessment and management of dysphagia pertinent to esophageal resection.

Minimally Invasive Approach for Wilms Tumor Treatment in a Small Child - A Case Report

Urology ◽  
2020 ◽  
Author(s):  
Alexandre Azevedo Ziomkowski ◽  
João Rafael Silva Simões Estrela ◽  
Nilo Jorge Carvalho Leão Barretto ◽  
Nilo César Leão Barretto
Keyword(s):  
Case Report ◽  
Minimally Invasive ◽  
Wilms Tumor ◽  
Small Child ◽  
Tumor Treatment ◽  
Minimally Invasive Approach ◽  
Invasive Approach
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