Modular DNA-Incorporated Aggregation-Induced Emission Probe for Sensitive Detection and Imaging of DNA Methyltransferase

2020 ◽  
Vol 3 (12) ◽  
pp. 9002-9011
Author(s):  
Jun Wu ◽  
Qinyu Hu ◽  
Qing Chen ◽  
Jun Dai ◽  
Xia Wu ◽  
...  
Keyword(s):  
Dna Methyltransferase ◽  
Sensitive Detection ◽  
Aggregation Induced Emission

Sensitive detection of DNA methyltransferase activity by transcription-mediated duplex-specific nuclease-assisted cyclic signal amplification

2015 ◽  
Vol 51 (73) ◽  
pp. 13968-13971 ◽  
Author(s):  
Yan Zhang ◽  
Wen-jing Xu ◽  
Ya-ping Zeng ◽  
Chun-yang Zhang
Keyword(s):  
Signal Amplification ◽  
Dna Methyltransferase ◽  
Sensitive Detection ◽  
Methyltransferase Activity

We develop transcription-mediated duplex-specific nuclease-assisted cyclic signal amplification for sensitive detection of DNA methyltransferase activity.

New ‘aggregation induced emission (AIE)’ active cyclometalated iridium(iii) based phosphorescent sensors: high sensitivity for mercury(ii) ions

2014 ◽  
Vol 43 (43) ◽  
pp. 16431-16440 ◽  
Author(s):  
Parvej Alam ◽  
Gurpreet Kaur ◽  
Clàudia Climent ◽  
Saleem Pasha ◽  
David Casanova ◽  
...  
Keyword(s):  
High Sensitivity ◽  
Sensitive Detection ◽  
Aggregation Induced Emission ◽  
Strategic Design ◽  
Mercuric Ions

Strategic design and syntheses of an AIE active bis-cyclometalatediridium(iii) complex were carried out for highly selective and sensitive detection of mercuric ions.

Detection of DNA methyltransferase activity using allosteric molecular beacons

The Analyst ◽  
2016 ◽  
Vol 141 (2) ◽  
pp. 579-584 ◽  
Author(s):  
Weiting Zhang ◽  
Xiaolong Zu ◽  
Yanling Song ◽  
Zhi Zhu ◽  
Chaoyong James Yang
Keyword(s):  
Dna Methylation ◽  
Dna Methyltransferase ◽  
Molecular Beacon ◽  
Molecular Beacons ◽  
Sensitive Detection ◽  
Methyltransferase Activity ◽  
Mtase Activity ◽  
Adenine Methylation ◽  
Methylation Patterns

Abnormal DNA methylation patterns caused by altered DNA methyltransferase (MTase) activity are closely associated with cancer. Herein, using DNA adenine methylation methyltransferase (Dam MTase) as a model analyte, we designed an allosteric molecular beacon (aMB) for sensitive detection of Dam MTase activity.

A fluorescent sensor based on aggregation-induced emission: highly sensitive detection of hydrazine and its application in living cell imaging

The Analyst ◽  
2018 ◽  
Vol 143 (18) ◽  
pp. 4298-4305 ◽  
Author(s):  
Jiabin Qiu ◽  
Yunxiang Chen ◽  
Shengjie Jiang ◽  
Hongyu Guo ◽  
Fafu Yang
Keyword(s):  
Living Cell ◽  
Cell Imaging ◽  
Fluorescent Sensor ◽  
Sensitive Detection ◽  
Aggregation Induced Emission ◽  
Highly Sensitive ◽  
Highly Sensitive Detection ◽  
Living Cell Imaging

A fluorescent sensor based on aggregation-induced emission for amines was prepared and its highly sensitive detection of hydrazine and application in living cell imaging were investigated in detail.

scholarly journals Single-ribonucleotide repair-mediated ligation-dependent cycling signal amplification for sensitive and specific detection of DNA methyltransferase

2018 ◽  
Vol 9 (28) ◽  
pp. 6053-6061 ◽  
Author(s):  
Li-juan Wang ◽  
Xiao Han ◽  
Chen-chen Li ◽  
Chun-yang Zhang
Keyword(s):  
Signal Amplification ◽  
Dna Methyltransferase ◽  
Sensitive Detection ◽  
Specific Detection ◽  
Mtase Activity

Specific and sensitive detection of DNA MTase activity can be achieved by a single-ribonucleotide repair-mediated ligation-dependent cycling signal amplification approach.

Self-Assembled Porous Nanoparticles Based on Silicone Polymer with Aggregation-induced Emission for Highly Sensitive Detection of Nitroaromatics

2021 ◽  
Author(s):  
Xiangzhong Zhao ◽  
Yan Liang ◽  
Ting Wang ◽  
Fangfang Li ◽  
Hua Wang
Keyword(s):  
Polymeric Materials ◽  
Sensitive Detection ◽  
Ideal Class ◽  
Fluorescent Chemosensors ◽  
Aggregation Induced Emission ◽  
Highly Sensitive ◽  
Fluorescent Materials ◽  
Porous Nanoparticles ◽  
Highly Sensitive Detection ◽  
Silicone Polymer

Aggregation-induced emission (AIE) -active polymeric materials have been regarded as an ideal class of fluorescent materials to be widely used as fluorescent chemosensors. Herein, we demonstrate a simple and effective...

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