Efficient Chemoenzymatic Synthesis of Optically Active Pregabalin from Racemic Isobutylsuccinonitrile

2019 ◽  
Vol 23 (9) ◽  
pp. 2042-2049 ◽  
Author(s):  
Qin Zhang ◽  
Zhe-Ming Wu ◽  
Shuang Liu ◽  
Xiao-Ling Tang ◽  
Ren-Chao Zheng ◽  
...  
Keyword(s):  
Optically Active ◽  
Chemoenzymatic Synthesis

Sequential biocatalytic resolution of (±)-trans-cyclohexane-1,2-diamine. Chemoenzymatic synthesis of an optically active polyamine

1996 ◽  
pp. 2471-2472 ◽  
Author(s):  
Ignacio Alfonso ◽  
Covadonga Astorga ◽  
Francisca Rebolledo ◽  
Vicente Gotor
Keyword(s):  
Optically Active ◽  
Chemoenzymatic Synthesis

Chemoenzymatic Synthesis of Optically Active Heterocyclic Homoallylic and Homopropargylic Alcohols.

ChemInform ◽  
2003 ◽  
Vol 34 (19) ◽  
Author(s):  
Satwinder Singh ◽  
Subodh Kumar ◽  
Swapandeep Singh Chimni
Keyword(s):  
Optically Active ◽  
Chemoenzymatic Synthesis ◽  
Homopropargylic Alcohols

Chemoenzymatic synthesis of optically active 1,2-disubstituted ferrocenes with planar chirality

2009 ◽  
Vol 20 (12) ◽  
pp. 1371-1377 ◽  
Author(s):  
Mounia Merabet-Khellasi ◽  
Louisa Aribi-Zouioueche ◽  
Olivier Riant
Keyword(s):  
Optically Active ◽  
Chemoenzymatic Synthesis ◽  
Planar Chirality

Chemoenzymatic synthesis of optically active phenolic 3,4-dihydropyridin-2-ones: a way to access enantioenriched 1,4-dihydropyridine and benzodiazepine derivatives

2017 ◽  
Vol 15 (24) ◽  
pp. 5171-5181 ◽  
Author(s):  
Susana Y. Torres ◽  
Rosario Brieva ◽  
Francisca Rebolledo
Keyword(s):  
Kinetic Resolution ◽  
Optically Active ◽  
Chemoenzymatic Synthesis ◽  
Benzodiazepine Derivatives

Kinetic resolution of 3,4-DHP-2-ones with Candida rugose lipase (CRL) has been possible due to the presence of a reactive phenolic ester in a remote position.

scholarly journals Chemoenzymatic synthesis and biological evaluation of enantiomerically enriched 1-(β-hydroxypropyl)imidazolium- and triazolium-based ionic liquids

2013 ◽  
Vol 9 ◽  
pp. 516-525 ◽  
Author(s):  
Paweł Borowiecki ◽  
Małgorzata Milner-Krawczyk ◽  
Jan Plenkiewicz
Keyword(s):  
Ionic Liquids ◽  
Vinyl Acetate ◽  
Propylene Oxide ◽  
Ring Opening ◽  
Biological Evaluation ◽  
Optically Active ◽  
Chemoenzymatic Synthesis ◽  
Alkyl Bromides ◽  
Wide Range ◽  
Synthesis And Biological Evaluation

Racemic 1-(β-hydroxypropyl)azoles were prepared by solvent-free direct regioselective ring opening of 1,2-propylene oxide with imidazole or 1,2,4-triazole. Lipase-catalyzed transesterification of alcohols with vinyl acetate resulted in kinetic enantiomers resolution. Separated (S)-enantiomers of (+)-1-(1H-imidazol-1-yl)propan-2-ol and (+)-1-(1H-1,2,4-triazol-1-yl)propan-2-ol were quaternized with alkyl bromides or iodides, yielding novel optically active ionic liquids. Racemic salts were tested against a wide range of microorganisms.

Chemoenzymatic Synthesis of Optically Active cis- and trans-2-(1H-Imidazol-1-yl)cycloalkanamines

2010 ◽  
Vol 2011 (6) ◽  
pp. 1057-1063 ◽  
Author(s):  
Sergio Alatorre-Santamaría ◽  
Vicente Gotor-Fernández ◽  
Vicente Gotor
Keyword(s):  
Optically Active ◽  
Chemoenzymatic Synthesis ◽  
Cis And Trans

A facile and convenient chemoenzymatic synthesis of optically active O-(4-methoxyphenyl)-glycidol and 1,2-diacyl-sn-glycerol

2005 ◽  
Vol 16 (10) ◽  
pp. 1855-1859 ◽  
Author(s):  
Ahmed Kamal ◽  
Mahendra Sandbhor ◽  
Ahmad Ali Shaik ◽  
M. Shaheer Malik
Keyword(s):  
Optically Active ◽  
Chemoenzymatic Synthesis

Chemoenzymatic Synthesis of Optically Active Diacylglycerophospholipid Hydroperoxides Derived from Arachidonic Acid

1993 ◽  
Vol 57 (9) ◽  
pp. 1615-1616 ◽  
Author(s):  
Naomichi Baba ◽  
Yasutami Shigeta ◽  
Yasuhiro Kishida ◽  
Shuhei Nakajima ◽  
Shoichi Tahara ◽  
...  
Keyword(s):  
Arachidonic Acid ◽  
Optically Active ◽  
Chemoenzymatic Synthesis
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