Process Research and Scale-Up Synthesis of 3-(4-Isobutyl-2-methylphenyl)propanal, a Safe and Uniquely Performing Perfumery Ingredient

2020 ◽  
Vol 24 (12) ◽  
pp. 2906-2914
Author(s):  
Martin A. Lovchik ◽  
Chi-Lam Tse ◽  
Simon Ellwood
Keyword(s):  
Scale Up ◽  
Process Research

Process Research and Initial Scale-Up of ABT-839: A Farnesyltransferase Inhibitor

2003 ◽  
pp. 59-69 ◽  
Author(s):  
Todd S. McDermott ◽  
Ramiya Premchandron ◽  
Anne E. Bailey ◽  
Lakshmi Bhagavatula ◽  
Howard E. Morton
Keyword(s):  
Scale Up ◽  
Process Research ◽  
Farnesyltransferase Inhibitor ◽  
Initial Scale

Process research toward scale-up and industrial preparation of RPR 109891 (Klerval™)

2006 ◽  
pp. 126-128
Author(s):  
James J. Mencel ◽  
Benoit J. Vanasse ◽  
Richard G. Woodward ◽  
James P. Sherbine ◽  
Robert C. Liu ◽  
...  
Keyword(s):  
Scale Up ◽  
Process Research ◽  
Industrial Preparation

Process Research and Development and Scale-up of a 4,4-Difluoro-3,3-dimethylproline Derivative

2008 ◽  
Vol 12 (2) ◽  
pp. 322-338 ◽  
Author(s):  
Francesco Rossi ◽  
Francesco Corcella ◽  
Francesco Saverio Caldarelli ◽  
Franco Heidempergher ◽  
Chiara Marchionni ◽  
...  
Keyword(s):  
Research And Development ◽  
Scale Up ◽  
Process Research

Process Research and Development of a MTP Inhibitor: Another Case of Disappearing Polymorphs upon Scale-up

2010 ◽  
Vol 14 (4) ◽  
pp. 878-882 ◽  
Author(s):  
Mahavir Prashad ◽  
Paul Sutton ◽  
Raeann Wu ◽  
Bin Hu ◽  
James Vivelo ◽  
...  
Keyword(s):  
Research And Development ◽  
Scale Up ◽  
Process Research

Process Research and Scale-Up for a β-3 Adrenergic Receptor Agonist

2004 ◽  
Vol 8 (4) ◽  
pp. 583-586 ◽  
Author(s):  
Brian C. Vanderplas ◽  
Keith M. DeVries ◽  
Darrell E. Fox ◽  
Jeffrey W. Raggon ◽  
Michael W. Snyder ◽  
...  
Keyword(s):  
Adrenergic Receptor ◽  
Receptor Agonist ◽  
Scale Up ◽  
Process Research ◽  
Adrenergic Receptor Agonist

Process Research and Scale-up of a Commercialisable Route to Maraviroc (UK-427,857), a CCR-5 Receptor Antagonist

2008 ◽  
Vol 12 (6) ◽  
pp. 1104-1113 ◽  
Author(s):  
Jens Åhman ◽  
Melissa Birch ◽  
Sarah J. Haycock-Lewandowski ◽  
James, Long ◽  
Alexander Wilder
Keyword(s):  
Receptor Antagonist ◽  
Scale Up ◽  
Process Research

scholarly journals Process Research and Scale-up of the κ-Opioid Receptor Agonist CJ-15,161 Drug Candidate

2006 ◽  
Vol 60 (9) ◽  
pp. 554-560 ◽  
Author(s):  
Brian M. Andresen ◽  
Stéphane Caron ◽  
Michel Couturier ◽  
Keith M. DeVries ◽  
Nga M. Do ◽  
...  
Keyword(s):  
Opioid Receptor ◽  
Receptor Agonist ◽  
Scale Up ◽  
Process Research ◽  
Drug Candidate ◽  
Opioid Receptor Agonist

NiAl precipitation in Fe-12w/o Cr-5w/o Ni-4w/o Al

1983 ◽  
Vol 41 ◽  
pp. 202-203
Author(s):  
L.E. Murr ◽  
J.S. Dunning ◽  
S. Shankar
Keyword(s):  
Solid Solution ◽  
Stainless Steel ◽  
Stainless Steels ◽  
Alloy Composition ◽  
Chromium Content ◽  
Scale Up ◽  
Optical Metallography ◽  
Property Evaluation ◽  
310 Stainless Steel ◽  
Microstructural Studies

Aluminum additions to conventional 18Cr-8Ni austenitic stainless steel compositions impart excellent resistance to high sulfur environments. However, problems are typically encountered with aluminum additions above about 1% due to embrittlement caused by aluminum in solid solution and the precipitation of NiAl. Consequently, little use has been made of aluminum alloy additions to stainless steels for use in sulfur or H2S environments in the chemical industry, energy conversion or generation, and mineral processing, for example.A research program at the Albany Research Center has concentrated on the development of a wrought alloy composition with as low a chromium content as possible, with the idea of developing a low-chromium substitute for 310 stainless steel (25Cr-20Ni) which is often used in high-sulfur environments. On the basis of workability and microstructural studies involving optical metallography on 100g button ingots soaked at 700°C and air-cooled, a low-alloy composition Fe-12Cr-5Ni-4Al (in wt %) was selected for scale up and property evaluation.

New Life for Process Research

1988 ◽  
Vol 33 (9) ◽  
pp. 802-803
Author(s):  
Edward S. Bordin
Keyword(s):  
Process Research
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