Novel Approach toward Water-Soluble Singlet Oxygen Monitors Based on Hybrid Inorganic–Organic Nanoclay

2021 ◽  
Author(s):  
Daniel K. Dinga ◽  
Michael Bredol ◽  
Ulrich Kynast
Keyword(s):  
Singlet Oxygen ◽  
Water Soluble ◽  
Novel Approach

scholarly journals Engineering cocrystals of Paliperidone with enhanced solubility and dissolution characteristics

2021 ◽  
Vol 71 (5) ◽  
pp. 393-409
Author(s):  
Earle Radha-Rani ◽  
Gadela Venkata-Radha
Keyword(s):  
Benzoic Acid ◽  
Aqueous Solubility ◽  
Water Soluble ◽  
X Ray Diffraction ◽  
X Ray ◽  
Water Soluble Drug ◽  
Novel Approach ◽  
Enhanced Solubility ◽  
Poorly Water Soluble ◽  
Poorly Water Soluble Drug

In the present study, co-crystals (CCs) of Paliperidone (PPD) with coformers like benzoic acid (BA) and P-amino benzoic acid (PABA) were synthesized and characterized to improve the physicochemical properties and dissolution rate. CCs were prepared by the solvent evaporation (SE) technique and were compared with the products formed by neat grinding (NG) and liquid assisted grinding (LAG) in their enhancement of solubility. The formation of CCs was confirmed by the IR spectroscopy, powder X-ray diffraction and thermal analysis methods. The saturation solubility studies indicate that the aqueous solubility of PPD-BA and PPD-PABA CCs was significantly improved to 1.343±0.162mg/ml and 1.964±0.452mg/ml, respectively, in comparison with the PPD solubility of 0.473mg/ml. This increase in solubility is 2.83-and 3.09-fold, respectively. PPD exhibited a poor dissolution of 37.8% in 60min, while the dissolution of the CCs improved tremendously to 96.07% and 89.65% in 60min. CCs of PPD with BA and PABA present a novel approach to overcome the solubility challenges of poorly water-soluble drug PPD.

Singlet oxygen generation by sonication using a water-soluble fullerene (C60) complex: a potential application for sonodynamic therapy

2020 ◽  
Vol 52 (12) ◽  
pp. 1387-1394
Author(s):  
Thi Lien Nguyen ◽  
Risa Katayama ◽  
Chie Kojima ◽  
Akikazu Matsumoto ◽  
Kazuhiko Ishihara ◽  
...  
Keyword(s):  
Singlet Oxygen ◽  
Potential Application ◽  
Fullerene C60 ◽  
Water Soluble ◽  
Sonodynamic Therapy ◽  
Oxygen Generation ◽  
Singlet Oxygen Generation

Determination of the lifetime of singlet oxygen in water-d2 using 9,10-anthracenedipropionic acid, a water-soluble probe

1980 ◽  
Vol 102 (17) ◽  
pp. 5590-5593 ◽  
Author(s):  
Barbara A. Lindig ◽  
Michael A. J. Rodgers ◽  
A. Paul Schaap
Keyword(s):  
Singlet Oxygen ◽  
Water Soluble

scholarly journals An optimized tracer-based approach for estimating organic carbon emissions from biomass burning in Ulaanbaatar, Mongolia

2020 ◽  
Vol 20 (5) ◽  
pp. 3231-3247 ◽  
Author(s):  
Jayant Nirmalkar ◽  
Tsatsral Batmunkh ◽  
Jinsang Jung
Keyword(s):  
Organic Carbon ◽  
Biomass Burning ◽  
Quantitative Estimation ◽  
Water Soluble ◽  
Atmospheric Particulate Matter ◽  
Coefficient Of Determination ◽  
Urban Site ◽  
Air Sampler ◽  
Novel Approach ◽  
The Impact

Abstract. The impact of biomass burning (BB) on atmospheric particulate matter of <2.5 µm diameter (PM2.5) at Ulaanbaatar, Mongolia, was investigated using an optimized tracer-based approach during winter and spring 2017. Integrated 24 h PM2.5 samples were collected on quartz-fiber filters using a 30 L min−1 air sampler at an urban site in Ulaanbaatar. The aerosol samples were analyzed for organic carbon (OC) and elemental carbon (EC), anhydrosugars (levoglucosan, mannosan, and galactosan), and water-soluble ions. OC was found to be the predominant species, contributing 64 % and 56 % to the quantified aerosol components in PM2.5 in winter and spring, respectively. BB was identified as a major source of PM2.5, followed by dust and secondary aerosols. Levoglucosan ∕ mannosan and levoglucosan ∕ K+ ratios indicate that BB in Ulaanbaatar mainly originated from the burning of softwood. Because of the large uncertainty associated with the quantitative estimation of OC emitted from BB (OCBB), a novel approach was developed to optimize the OC ∕ levoglucosan ratio for estimating OCBB. The optimum OC ∕ levoglucosan ratio in Ulaanbaatar was obtained by regression analysis between OCnon-BB (OCtotal–OCBB) and levoglucosan concentrations that gives the lowest coefficient of determination (R2) and slope. The optimum OC ∕ levoglucosan ratio was found to be 27.6 and 18.0 for winter and spring, respectively, and these values were applied in quantifying OCBB. It was found that 68 % and 63 % of the OC were emitted from BB during winter and spring, respectively. This novel approach can also be applied by other researchers to quantify OCBB using their own chemical measurements. In addition to OCBB, sources of OCnon-BB were also investigated through multivariate correlation analysis. It was found that OCnon-BB originated mainly from coal burning, vehicles, and vegetative emissions.

ChemInform Abstract: Synthesis and Photooxidation of Sodium 1,3-Cyclohexadiene-1,4- diethanoate: A New Colorless and Water-Soluble Trap of Singlet Oxygen.

ChemInform ◽  
2010 ◽  
Vol 27 (21) ◽  
pp. no-no
Author(s):  
V. NARDELLO ◽  
N. AZAROUAL ◽  
I. CERVOISE ◽  
G. VERMEERSCH ◽  
J.-M. AUBRY
Keyword(s):  
Singlet Oxygen ◽  
Water Soluble
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