Precisely Controlled Three-Dimensional Gold Nanoparticle Assembly Based on Spherical Bacteriophage Scaffold for Molecular Sensing via Surface-Enhanced Raman Scattering

2021 ◽  
Vol 125 (4) ◽  
pp. 2502-2510
Author(s):  
Myeong Jin Jeon ◽  
Xingyi Ma ◽  
Jong Uk Lee ◽  
Hyejin Roh ◽  
Conrad C. Bagot ◽  
...  
2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Li Yuan ◽  
Jinghuai Fang ◽  
Yonglong Jin ◽  
Chaonan Wang ◽  
Tian Xu

We fabricated a simple, cheap, and functional surface enhanced Raman scattering substrate for biomedical application. Hot spots between two close silver nanoparticles distributed in the skeleton of a three-dimensional porous membrane, especially in the pores, were formed. The dual poles of micropores in the membrane were discussed. The pores could protect the silver nanoparticles in the pores from being oxidized, which makes the membrane effective for a longer period of time. In addition,Staphylococcus aureuscells could be trapped by the micropores and then the Raman signal became stronger, indicating that the functional surface enhanced Raman scattering substrate is reliable.


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