Mechanistic Insight on BioIL-Induced Structural Alterations in DMPC Lipid Bilayer

2021 ◽  
Author(s):  
Shobhna ◽  
Monika Kumari ◽  
Hemant K. Kashyap
Keyword(s):  
Lipid Bilayer ◽  
Structural Alterations ◽  
Mechanistic Insight

Freeze-Fractured Studies on the Myocardial Cell Membrane Under Varying Degrees of Temperature During Calcium Paradox

1980 ◽  
Vol 38 ◽  
pp. 632-633
Author(s):  
M. Ashraf ◽  
Ross Lepera ◽  
M. Onda ◽  
Y. Hirohata ◽  
J. Benedict
Keyword(s):  
Cell Membrane ◽  
Lipid Bilayer ◽  
Morphological Changes ◽  
Myocardial Cell ◽  
Cellular Damage ◽  
Calcium Paradox ◽  
Free Medium ◽  
Structural Alterations ◽  
Intracellular Enzymes ◽  
Irreversible Injury

Reperfusion of hearts that are initially perfused with Ca-H-free medium, with normal Ca++-containing medium (called calcium paradox), is known to cause an irreversible injury to the cells. However, if the temperature of Ca-H-free medium is kept below normal temperature, the re introduction of Ca++ induces release of less intracellular enzymes and reduced amount of injury (1-2). This leads to a suggestion that hypothermia may minimize the structural alterations in the cell membrane (CM) to avoid cellular damage during calcium paradox. This study is aimed to elucidate the morphological changes in the cell manbrane lipid bilayer during Ca++ paradox.

Invited Review: Understanding airway pathophysiology with computed tomograpy

2003 ◽  
Vol 95 (2) ◽  
pp. 854-862 ◽  
Author(s):  
Robert H. Brown ◽  
Wayne Mitzner
Keyword(s):  
Pulmonary Function Tests ◽  
Direct Methods ◽  
Small Airways ◽  
High Resolution Computed Tomography ◽  
Structural Alterations ◽  
The Past ◽  
Mechanistic Insight ◽  
Airway Pathology ◽  
Large Airways

Conventional pulmonary function tests are limited in the mechanistic insight that they can provide by the fact that they can only provide average measures of lung function. For example, a measurement of decreased expiratory flow assessed with conventional spirometry could result from narrowed large airways, narrowed small airways, closed airways, altered elasticity, or regional heterogeneities in parenchyma or airways. To examine specific mechanisms and pathology in the airways, a method is required that can actually look at specific individual airways. Over the past decade, several more direct methods of assessing specific mechanisms and structural alterations in normal airways and airway pathology in asthma have become available for such purposes. One such method is high-resolution computed tomography (HRCT), a method that allows the study of multiple individual airways during either contraction to closure or relaxation in real time, as well as changes in airway size with changes in lung volume. Although other imaging modalities have the potential to image airways in vivo, none presently has the convenience and the accessibility coupled with the resolution required to visualize the parenchymal airways in vivo. Although HRCT may never be widely utilized for routine measurements or screening, because of radiation exposure, cost issues, and a limited ability to follow changes over extended time periods, the method has distinct and unique advantages in quantifying the behavior of airways in vivo. In this mini-review, we focus on these capabilities of HRCT by briefly reviewing highlights of experimental results from several canine and human studies.

Mechanistic Insight into Patterned Supported Lipid Bilayer Self-Assembly

Langmuir ◽  
2012 ◽  
Vol 28 (38) ◽  
pp. 13652-13659 ◽  
Author(s):  
Matthew K. Strulson ◽  
Joshua A. Maurer
Keyword(s):  
Lipid Bilayer ◽  
Self Assembly ◽  
Supported Lipid Bilayer ◽  
Mechanistic Insight ◽  
Insight Into

Squeezing a Synthetic Ionophore and Mechanistic Insight Out of a Lipid Bilayer

1999 ◽  
Vol 121 (44) ◽  
pp. 10440-10441 ◽  
Author(s):  
Sijbren Otto ◽  
Manette Osifchin ◽  
Steven L. Regen
Keyword(s):  
Lipid Bilayer ◽  
Mechanistic Insight ◽  
Synthetic Ionophore

Arylation of enelactams using TIPSOTf: reaction scope and mechanistic insight

2021 ◽  
Author(s):  
Tomasz J. Idzik ◽  
Zofia M. Myk ◽  
Łukasz Struk ◽  
Magdalena Perużyńska ◽  
Gabriela Maciejewska ◽  
...  
Keyword(s):  
Reaction Mechanism ◽  
Multinuclear Nmr ◽  
Mechanistic Insight ◽  
Nmr Study ◽  
Wide Range

Triisopropylsilyltrifluoromethanesulfonate can be effectively used for the arylation of a wide range of enelactams. The multinuclear NMR study provided deep insights into the reaction mechanism.

Structural Alterations in the Clinical Evaluation of Cirrhosis

1956 ◽  
Vol 30 (3) ◽  
pp. 357-372 ◽  
Author(s):  
Fenton Schaffner ◽  
Hans Popper ◽  
Mario Dalla Torre
Keyword(s):  
Clinical Evaluation ◽  
Structural Alterations

750 Structural alterations of large intestinal wall in patients with chronic heart failure of different classes

2006 ◽  
Vol 5 (1) ◽  
pp. 177-177
Author(s):  
A RYLOVA ◽  
G ARUTYUNOV ◽  
L KAFARSKAYA ◽  
N SAVELOV ◽  
N BYLOVA ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Intestinal Wall ◽  
Structural Alterations

In-vivo topography of structural alterations of the anterior cingulate gyrus in schizophrenia

2007 ◽  
Vol 40 (05) ◽  
Author(s):  
T Zetzsche ◽  
UW Preuss ◽  
T Frodl ◽  
D Watz ◽  
G Schmitt ◽  
...  
Keyword(s):  
Anterior Cingulate ◽  
Cingulate Gyrus ◽  
Anterior Cingulate Gyrus ◽  
Structural Alterations
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